Efficacy of the Plantago Major L. Syrup on Radiation Induced Oral Mucositis in Head and Neck Cancer Patients: A Randomized, Double Blind, Placebo-Controlled Clinical Trial

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Efficacy of the Plantago Major L. Syrup on Radiation Induced Oral Mucositis in Head and Neck Cancer Patients: A Randomized, Double Blind, Placebo-Controlled Clinical Trial Publisher Pubmed

Soltani GM¹ ; Hemati S² ; Sarvizadeh M² ; Kamalinejad M³ ; Tafazoli V⁴ ; Latifi SA¹

Show Affiliations

1. Traditional and Complementary Medicine Research Center (TCMRC), Arak University of Medical Sciences, Arak, Iran
2. Department of Radiation Oncology, Isfahan University of Medical Sciences, Isfahan, Iran
3. School of Pharmacy, Shahid Beheshti University of Medical Science, Tehran, Iran
4. Department of Persian Medicine, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran

Source: Complementary Therapies in Medicine Published:2020

Abstract

Introduction: Oral mucositis is a complication of radiation therapy in cancer patients. We designed a trial to evaluate efficacy of plantago major on symptoms of radiation induced mucositis in cancer patients. Methods: In this randomized double blind, placebo-controlled trial 23 patients received plantago major syrup as intervention group and 23 patients received placebo syrup as control group for 7 weeks. Outcome measures were severity of mucositis according to WHO scale and severity of patients' pain assessed by visual analogue scale. Results: Severity of mucositis were significantly lower in intervention group compared to placebo group (p value<0.05). Also patients in intervention group experienced significantly less pain compared to placebo group during radiotherapy period (p value<0.05) Conclusion: Plantago major L syrup was effective on the reduction of the symptoms of radiation induced mucositis in patients with head and neck cancers. © 2020 Elsevier Ltd

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Style	Citing Format
MLA	Soltani GM, et al.. "Efficacy of the Plantago Major L. Syrup on Radiation Induced Oral Mucositis in Head and Neck Cancer Patients: A Randomized, Double Blind, Placebo-Controlled Clinical Trial." Complementary Therapies in Medicine, vol. 51, no. , 2020, pp. -.
APA	Soltani GM, Hemati S, Sarvizadeh M, Kamalinejad M, Tafazoli V, Latifi SA (2020). Efficacy of the Plantago Major L. Syrup on Radiation Induced Oral Mucositis in Head and Neck Cancer Patients: A Randomized, Double Blind, Placebo-Controlled Clinical Trial. Complementary Therapies in Medicine, 51(), -.
Chicago	Soltani GM, Hemati S, Sarvizadeh M, Kamalinejad M, Tafazoli V, Latifi SA. "Efficacy of the Plantago Major L. Syrup on Radiation Induced Oral Mucositis in Head and Neck Cancer Patients: A Randomized, Double Blind, Placebo-Controlled Clinical Trial." Complementary Therapies in Medicine 51, no. (2020): -.
Harvard	Soltani GM et al. (2020) 'Efficacy of the Plantago Major L. Syrup on Radiation Induced Oral Mucositis in Head and Neck Cancer Patients: A Randomized, Double Blind, Placebo-Controlled Clinical Trial', Complementary Therapies in Medicine, 51(), pp. -.
Vancouver	Soltani GM, Hemati S, Sarvizadeh M, Kamalinejad M, Tafazoli V, Latifi SA. Efficacy of the Plantago Major L. Syrup on Radiation Induced Oral Mucositis in Head and Neck Cancer Patients: A Randomized, Double Blind, Placebo-Controlled Clinical Trial. Complementary Therapies in Medicine. 2020;51():-.
BibTex	@article{ author = {Soltani GM and Hemati S and Sarvizadeh M and Kamalinejad M and Tafazoli V and Latifi SA}, title = {Efficacy of the Plantago Major L. Syrup on Radiation Induced Oral Mucositis in Head and Neck Cancer Patients: A Randomized, Double Blind, Placebo-Controlled Clinical Trial}, journal = {Complementary Therapies in Medicine}, volume = {51}, number = {}, pages = {-}, year = {2020} }
RIS	TY - JOUR AU - Soltani GM AU - Hemati S AU - Sarvizadeh M AU - Kamalinejad M AU - Tafazoli V AU - Latifi SA TI - Efficacy of the Plantago Major L. Syrup on Radiation Induced Oral Mucositis in Head and Neck Cancer Patients: A Randomized, Double Blind, Placebo-Controlled Clinical Trial JO - Complementary Therapies in Medicine VL - 51 IS - SP - EP - PY - 2020 ER -

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