Efficacy of the Plantago Major L. Syrup on Radiation Induced Oral Mucositis in Head and Neck Cancer Patients: A Randomized, Double Blind, Placebo-Controlled Clinical Trial

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):

Share By

Efficacy of the Plantago Major L. Syrup on Radiation Induced Oral Mucositis in Head and Neck Cancer Patients: A Randomized, Double Blind, Placebo-Controlled Clinical Trial Publisher Pubmed

Soltani GM¹ ; Hemati S² ; Sarvizadeh M² ; Kamalinejad M³ ; Tafazoli V⁴ ; Latifi SA¹

Source: Complementary Therapies in Medicine Published:2020

Abstract

Introduction: Oral mucositis is a complication of radiation therapy in cancer patients. We designed a trial to evaluate efficacy of plantago major on symptoms of radiation induced mucositis in cancer patients. Methods: In this randomized double blind, placebo-controlled trial 23 patients received plantago major syrup as intervention group and 23 patients received placebo syrup as control group for 7 weeks. Outcome measures were severity of mucositis according to WHO scale and severity of patients' pain assessed by visual analogue scale. Results: Severity of mucositis were significantly lower in intervention group compared to placebo group (p value<0.05). Also patients in intervention group experienced significantly less pain compared to placebo group during radiotherapy period (p value<0.05) Conclusion: Plantago major L syrup was effective on the reduction of the symptoms of radiation induced mucositis in patients with head and neck cancers. © 2020 Elsevier Ltd

Related Docs

View other Related Docs

1. The Effects of Herbal Medicines on Cancer Therapy-Induced Oral Mucositis: A Literature Review, Phytotherapy Research (2022)

2. Comparative Study of the Effect of Licorice Muco-Adhesive Film on Radiotherapy Induced Oral Mucositis, a Randomized Controlled Clinical Trial, The Gulf journal of oncology (2021)

3. The Role of Sucralfate Oral Suspension in Prevention of Radiation Induced Mucositis, Journal of Research in Medical Sciences (2008)

Experts (# of related papers)

View all Related Experts

Simin Hemati (5)

Fahimeh Pakravan (4)

Other Related Docs

4. Investigating the Effect of Aloe Vera on the Prevention and Treatment of Radiotherapy‑Induced Oral Mucositis in Patients With Head‑And‑Neck Cancer, Journal of Research in Medical Sciences (2024)

5. Comparison of Triamcinolone Acetonide Mucoadhesive Film With Licorice Mucoadhesive Film on Radiotherapy-Induced Oral Mucositis: A Randomized Double-Blinded Clinical Trial, Asia-Pacific Journal of Clinical Oncology (2017)

6. A Novel Formulation for Radiotherapy-Induced Oral Mucositis: Triamcinolone Acetonide Mucoadhesive Film, Journal of Research in Medical Sciences (2019)

7. Topical Use of Chicory Root Extract Gel on the Incidence and Severity of Radiodermatitis in Breast Cancer Patients: A Randomized Controled Trial, Supportive Care in Cancer (2024)

8. Double-Blinded, Randomized, Placebo-Controlled Study to Evaluate the Effectiveness of Green Tea in Preventing Acute Gastrointestinal Complications Due to Radiotherapy, Journal of Research in Medical Sciences (2014)

9. Impact of Curcumin Supplementation on Radiation Dermatitis Severity: A Systematic Review and Meta-Analysis of Randomized Controlled Trials, Asian Pacific Journal of Cancer Prevention (2023)

10. Vitamin D Deficiency Is Associated With the Severity of Radiation-Induced Proctitis in Cancer Patients, International Journal of Radiation Oncology Biology Physics (2015)

11. The Efficacy of Oral Hydrogel Containing Hyaluronic Acid, Polyvinylpyrrolidone, and Glycyrrhizin for Prevention and Treatment of Oral Mucositis Induced by Chemotherapy, Journal of Isfahan Medical School (2021)

12. A Review of the Quality of Extant Clinical Practice Guidelines in Cancer Therapy-Induced Mucositis, International Journal of Cancer Management (2017)

13. The Effect of Glutamine Intake on Complications of Colorectal and Colon Cancer Treatment: A Systematic Review, Journal of Research in Medical Sciences (2015)

14. The Effect of Plantago Major Hydroalcoholic Extract on the Healing of Diabetic Foot and Pressure Ulcers: A Randomized Open-Label Controlled Clinical Trial, International Journal of Lower Extremity Wounds (2024)

15. Effects of Probiotics With or Without Honey on Radiation-Induced Diarrhea, International Journal of Radiation Research (2016)

16. Clinical Evaluation of Oral Curcumin in Prevention of Acute Dermatitis in Breast Cancer Radiotherapy, Journal of Isfahan Medical School (2011)

17. A Comparative Study of Oral and Pharyngeal Adverse Events in Breast Cancer Patients Undergoing Conventional and Hypofractionated Radiotherapy; [بررسی و مقایسهی بروز عارضهی دهان و حلق در بیماران مبتلا به سرطان پستان تحت پرتودرمانی در دو تکنیک کانونشنال و هایپوفرکشن], Journal of Isfahan Medical School (2024)

18. Comparison of Oral Candidiasis Characteristics in Head-And-Neck Cancer Patients Before and During Radiotherapy, Dental Research Journal (2023)

19. The Effect of Oral Zinc Sulfate on Prevention of Chemotherapy-Induced Oral Mucositis in Breast Cancer Patients Treated With Adriamycin and Cyclophosphamide; a Double-Blind Randomized Clinical Trial, Journal of Nephropharmacology (2023)

20. Medicinal Plants, Effective Plant Compounds (Compositions) and Their Effects on Stomach Cancer, International Journal of Preventive Medicine (2017)

Style	Citing Format
MLA	Soltani GM, et al.. "Efficacy of the Plantago Major L. Syrup on Radiation Induced Oral Mucositis in Head and Neck Cancer Patients: A Randomized, Double Blind, Placebo-Controlled Clinical Trial." Complementary Therapies in Medicine, vol. 51, no. , 2020, pp. -.
APA	Soltani GM, Hemati S, Sarvizadeh M, Kamalinejad M, Tafazoli V, Latifi SA (2020). Efficacy of the Plantago Major L. Syrup on Radiation Induced Oral Mucositis in Head and Neck Cancer Patients: A Randomized, Double Blind, Placebo-Controlled Clinical Trial. Complementary Therapies in Medicine, 51(), -.
Chicago	Soltani GM, Hemati S, Sarvizadeh M, Kamalinejad M, Tafazoli V, Latifi SA. "Efficacy of the Plantago Major L. Syrup on Radiation Induced Oral Mucositis in Head and Neck Cancer Patients: A Randomized, Double Blind, Placebo-Controlled Clinical Trial." Complementary Therapies in Medicine 51, no. (2020): -.
Harvard	Soltani GM et al. (2020) 'Efficacy of the Plantago Major L. Syrup on Radiation Induced Oral Mucositis in Head and Neck Cancer Patients: A Randomized, Double Blind, Placebo-Controlled Clinical Trial', Complementary Therapies in Medicine, 51(), pp. -.
Vancouver	Soltani GM, Hemati S, Sarvizadeh M, Kamalinejad M, Tafazoli V, Latifi SA. Efficacy of the Plantago Major L. Syrup on Radiation Induced Oral Mucositis in Head and Neck Cancer Patients: A Randomized, Double Blind, Placebo-Controlled Clinical Trial. Complementary Therapies in Medicine. 2020;51():-.
BibTex	@article{ author = {Soltani GM and Hemati S and Sarvizadeh M and Kamalinejad M and Tafazoli V and Latifi SA}, title = {Efficacy of the Plantago Major L. Syrup on Radiation Induced Oral Mucositis in Head and Neck Cancer Patients: A Randomized, Double Blind, Placebo-Controlled Clinical Trial}, journal = {Complementary Therapies in Medicine}, volume = {51}, number = {}, pages = {-}, year = {2020} }
RIS	TY - JOUR AU - Soltani GM AU - Hemati S AU - Sarvizadeh M AU - Kamalinejad M AU - Tafazoli V AU - Latifi SA TI - Efficacy of the Plantago Major L. Syrup on Radiation Induced Oral Mucositis in Head and Neck Cancer Patients: A Randomized, Double Blind, Placebo-Controlled Clinical Trial JO - Complementary Therapies in Medicine VL - 51 IS - SP - EP - PY - 2020 ER -

Science Communicator Platform

Authors

Abstract