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Induction and Maintenance of Anesthesia With Propofol May Have More Stabilizing Effects on the Hemodynamic Status Compared to Isoflurane in Patients With Placental Adhesion Who Underwent Cesarean Section: A Pilot Study



Sajedi P1 ; Emami A2
Authors
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Authors Affiliations
  1. 1. Department of Anesthesia and Intensive Care, Faculty of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
  2. 2. Faculty of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

Source: Journal of Mazandaran University of Medical Sciences Published:2024

Abstract

Background and purpose: Cesarean hemorrhage is a common but preventable cause of maternal death and placenta invasion is a major cause of cesarean hemorrhage. This study aimed to compare inhalation anesthesia with isoflurane and Propofol anesthesia in cesarean bleeding in these patients. Materials and methods: This study was conducted as a randomized clinical trial with 15 placental adhesion patients who were candidates for cesarean section. Five patients were excluded by applying the exclusion criteria, and out of the other 10 patients, 5 underwent cesarean section with isoflurane and 5 with Propofol. Results: The comparison indicated that the volume of suctioned blood, the number of gasses used, the volume of serum received, packed-cell received and urinary output were significantly lower in the Propofol group (P≤0.05). Systolic and diastolic blood pressures were significantly close to basic figures in the Propofol group (P≤0.05), Heart rate, respiratory rate, temperature, and O2 saturation were not significantly different between the two groups (P≥0.05). Conclusion: The findings of this study recommended propofol anesthesia for the cesarian section in placenta adhesion. However, further studies with more cases are needed. © 2024, Mazandaran University of Medical Sciences. All rights reserved.
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