Isfahan University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Evaluation of Physical, Mechanical and Biological Properties of Bioglass/Titania Scaffold Coated With Poly (3-Hydroxybutyrate)-Chitosan for Bone Tissue Engineering Applications Publisher



Parvizifard M1 ; Karbasi S1 ; Salehi H2 ; Soleymani Eil Bakhtiari S3
Authors
Show Affiliations
Authors Affiliations
  1. 1. Department of Biomaterials and Tissue Engineering, School of Advanced Technology in Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
  2. 2. Department of Anatomical Sciences and Molecular Biology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
  3. 3. Advanced Materials Research Center, Department of Materials Engineering, Najafabad Branch, Islamic Azad University, Najafabad, Iran

Source: Materials Technology Published:2020


Abstract

In this work the scaffolds were made by foam replication method. The results from SEM showed that scaffolds with and without coating have high porosity and well-interconnected pore structure, and the polymer coating caused a significant increase in the mechanical properties from 0.01 Mpa to 0.19 Mpa. This coating also had a significant effect on the reduction of the contact angle, which due to the presence of Cs. The bioactivity in simulated body fluid (SBF) have shown that polymer coating did not have any negative effect on the bioactivity of the scaffolds. The results of Antibacterial test on both Gram-positive and Gram-negative bacteria on the scaffolds with PHB/Cs coating were observed. The results of cell compatibility showed that the growth and adhesion of MG63 cells on the scaffolds with PHB/Cs coating were higher. The results of this study represented that 45S5 bioglass/titania based scaffold with PHB/Cs coating is a promising candidate for bone tissue engineering applications. © 2019, © 2019 Informa UK Limited, trading as Taylor & Francis Group.
Related Docs
View other Related Docs
1. Physical, Mechanical and Biological Performance of Phb-Chitosan/Mwcnts Nanocomposite Coating Deposited on Bioglass Based Scaffold: Potential Application in Bone Tissue Engineering, International Journal of Biological Macromolecules (2020)
2. Evaluation of Physical, Mechanical and Biological Properties of Β-Tri-Calcium Phosphate/Poly-3-Hydroxybutyrate Nano Composite Scaffold for Bone Tissue Engineering Application, Materials Technology (2021)
3. The Effect of Coating Type on Mechanical Properties and Controlled Drug Release of Pcl/Zein Coated 45S5 Bioactive Glass Scaffolds for Bone Tissue Engineering, Materials Science and Engineering C (2015)
4. Evaluation of the Effects of Β-Tricalcium Phosphate on Physical, Mechanical and Biological Properties of Poly (3-Hydroxybutyrate)/Chitosan Electrospun Scaffold for Cartilage Tissue Engineering Applications, Materials Technology (2019)
5. Biodegradation and Cellular Evaluation of Aligned and Random Poly (3-Hydroxybutyrate)/Chitosan Electrospun Scaffold for Nerve Tissue Engineering Applications, Materials Technology (2020)
6. Physical, Mechanical, and Biological Performance of Chitosan-Based Nanocomposite Coating Deposited on the Polycaprolactone-Based 3D Printed Scaffold: Potential Application in Bone Tissue Engineering, International Journal of Biological Macromolecules (2023)
7. Modified Poly(3-Hydroxybutyrate)-Based Scaffolds in Tissue Engineering Applications: A Review, International Journal of Biological Macromolecules (2021)
8. Mechanical Properties and Drug Release Behavior of Pcl/Zein Coated 45S5 Bioactive Glass Scaffolds for Bone Tissue Engineering Application, Data in Brief (2015)
Experts (# of related papers)
View all Related Experts
Saeed Karbasi (91)
Mohammad Rafienia (56)
Other Related Docs
9. Evaluation of Mechanical Property and Bioactivity of Nano-Bioglass 45S5 Scaffold Coated With Poly-3-Hydroxybutyrate, Journal of Materials Science: Materials in Medicine (2015)
10. Evaluation of the Effects of Nano-Tio2 on Bioactivity and Mechanical Properties of Nano Bioglass-P3hb Composite Scaffold for Bone Tissue Engineering, Journal of Materials Science: Materials in Medicine (2016)
11. Biological Evaluation of the Effects of Hyaluronic Acid on Poly (3-Hydroxybutyrate) Based Electrospun Nanocomposite Scaffolds for Cartilage Tissue Engineering Application, Materials Technology (2020)
12. Evaluation of Physical and Mechanical Properties of Fi-Tri-Calcium Phosphate/Poly-3-Hydroxybutyrate Nanocomposite Scaffold for Bone Tissue Engineering Application, Scientia Iranica (2017)
13. Preparation and Characterization of 3D Nanocomposite Scaffold From Bioactive Glass/Β-Tricalcium Phosphate Via Robocasting Method for Bone Tissue Engineering, Journal of Non-Crystalline Solids (2022)
14. Baghdadite/Polycaprolactone Nanocomposite Scaffolds: Preparation, Characterisation, and in Vitro Biological Responses of Human Osteoblast-Like Cells (Saos-2 Cell Line), Materials Technology (2020)
15. Evaluation of the Effects of Chitosan/Multiwalled Carbon Nanotubes Composite on Physical, Mechanical and Biological Properties of Polymethyl Methacrylate-Based Bone Cements, Materials Technology (2020)
16. Synergetic Effect of Bioglass and Nano Montmorillonite on 3D Printed Nanocomposite of Polycaprolactone/Gelatin in the Fabrication of Bone Scaffolds, International Journal of Biological Macromolecules (2024)
17. Fabrication and Finite Element Simulation of Antibacterial 3D Printed Poly L-Lactic Acid Scaffolds Coated With Alginate/Magnesium Oxide for Bone Tissue Regeneration, International Journal of Biological Macromolecules (2023)
18. Synthesis and Characterization of Bioactive Glass Coated Forsterite Scaffold for Tissue Engineering Applications, Journal of Alloys and Compounds (2017)
19. Evaluation of the Effects of Keratin on Physical, Mechanical and Biological Properties of Poly (3-Hydroxybutyrate) Electrospun Scaffold: Potential Application in Bone Tissue Engineering, European Polymer Journal (2020)
20. Review of Recent Advances in Bone Scaffold Fabrication Methods for Tissue Engineering for Treating Bone Diseases and Sport Injuries, Tissue and Cell (2024)
21. Mechanical Property of Poly (3-Hydroxybutyrate)/Bioglass Nanocomposite Scaffolds for Bone Tissue Engineering, IFMBE Proceedings (2010)
22. Ultra-Thin Electrospun Nanocomposite Scaffold of Poly (3-Hydroxybutyrate)-Chitosan/Magnetic Mesoporous Bioactive Glasses for Bone Tissue Engineering Applications, International Journal of Biological Macromolecules (2024)
23. Development of Porous Photopolymer Resin-Swcnt Produced by Digital Light Processing Technology Using for Bone Femur Application, Archives of Bone and Joint Surgery (2021)
24. Fabrication of 3D Porous Polyurethane-Graphene Oxide Scaffolds by a Sequential Two-Step Processing for Non-Load Bearing Bone Defects, Physica Scripta (2024)
25. A Femoral Shape Porous Scaffold Bio-Nanocomposite Fabricated Using 3D Printing and Freeze-Drying Technique for Orthopedic Application, Materials Chemistry and Physics (2022)
26. Evaluation of the Effects of Nano-Tio2 on Physical and Mechanical Properties of Nano-Bioglass 45S5 Scaffold for Bone Tissue Engineering, Scientia Iranica (2015)
27. Preparation and Characterization of Silk-Chitosan Composite As a Three- Dimensional Tool for Culturing Osteoblast-Like Cells, Journal of Isfahan Medical School (2015)
28. Evaluation of Mg63 Cells Behavior With Electrospun Nanocomposite Scaffolds of Polycaprolactone and Carbon Quantum Dot Containing Captopril for Bone Tissue Engineering, Journal of Knowledge and Health in Basic Medical Sciences (2020)
29. Effects of Bioglass Nanoparticles on Bioactivity and Mechanical Property of Poly(3-Hydroxybutirate) Scaffolds, Scientia Iranica (2013)
30. Keratin-Containing Scaffolds for Tissue Engineering Applications: A Review, Journal of Biomaterials Science, Polymer Edition (2024)
31. The Influence of Bioglass Nanoparticles on the Biodegradation and Biocompatibility of Poly (3-Hydroxybutyrate) Scaffolds, International Journal of Artificial Organs (2012)
32. Effect of Cellulose Nanofibers on Polyhydroxybutyrate Electrospun Scaffold for Bone Tissue Engineering Applications, International Journal of Biological Macromolecules (2022)
33. The Impact of 45S5 Bioglass Vs. Β-Tcp Nanoparticles Ratio on Rheological Behavior of Formulated Printing Inks and 3D Printed Polycaprolactone-Based Scaffolds Final Properties, Heliyon (2024)
34. Evaluation of the Effects of Starch on Polyhydroxybutyrate Electrospun Scaffolds for Bone Tissue Engineering Applications, International Journal of Biological Macromolecules (2021)
35. Fabrication and Characterization of Hydroxyapatite-Coated Forsterite Scaffold for Tissue Regeneration Applications, Bulletin of Materials Science (2015)
36. Effects of Nano-Bioactive Glass on Structural, Mechanical and Bioactivity Properties of Poly (3-Hydroxybutyrate) Electrospun Scaffold for Bone Tissue Engineering Applications, Materials Technology (2019)
37. Enhancing the Biological Characteristics of Aminolysis Surface-Modified 3D Printed Nanocomposite Polycaprolactone/Nanohydroxyapatite Scaffold Via Gelatin Biomacromolecule Immobilization: An in Vitro and in Vivo Study, Colloids and Surfaces B: Biointerfaces (2025)
38. Natural Hydroxyapatite/Diopside Nanocomposite Scaffold for Bone Tissue Engineering Applications: Physical, Mechanical, Bioactivity and Biodegradation Evaluation, Materials Technology (2022)
39. Physical and Mechanical Properties of a Poly-3-Hydroxybutyratecoated Nanocrystalline Hydroxyapatite Scaffold for Bone Tissue Engineering, Journal of Porous Materials (2012)
40. Preparation of a Novel Biodegradable Nanocomposite Scaffold Based on Poly (3-Hydroxybutyrate)/Bioglass Nanoparticles for Bone Tissue Engineering, Journal of Materials Science: Materials in Medicine (2010)
41. Incorporation of Nanohydroxyapatite and Vitamin D3 Into Electrospun Pcl/Gelatin Scaffolds: The Influence on the Physical and Chemical Properties and Cell Behavior for Bone Tissue Engineering, Polymers for Advanced Technologies (2018)
42. A New Approach to Fabrication of Cs/Bg/Cnt Nanocomposite Scaffold Towards Bone Tissue Engineering and Evaluation of Its Properties, Applied Surface Science (2015)
43. Potential of an Electrospun Composite Scaffold of Poly (3-Hydroxybutyrate)-Chitosan/Alumina Nanowires in Bone Tissue Engineering Applications, Materials Science and Engineering C (2019)
44. Tunable Cellular Interactions and Physical Properties of Nanofibrous Pcl-Forsterite: Gelatin Scaffold Through Sequential Electrospinning, Composites Science and Technology (2013)
45. A 3D Nanostructured Calcium-Aluminum-Silicate Scaffold With Hierarchical Meso-Macroporosity for Bone Tissue Regeneration: Fabrication, Sintering Behavior, Surface Modification and in Vitro Studies, Journal of the European Ceramic Society (2021)
46. Uio-66 Metal-Organic Framework (Mof) As an Osteogenic Stimulant in the Poly-3-Hydroxybutyrate-Zein/Uio-66 Electrospun Composite Scaffold for Bone Tissue Engineering Applications, Journal of Polymers and the Environment (2025)
47. The Journey of Multifunctional Bone Scaffolds Fabricated From Traditional Toward Modern Techniques, Bio-Design and Manufacturing (2020)
48. A Novel Nano-Composite Scaold for Cartilage Tissue Engineering, Scientia Iranica (2018)
49. Effects of Adding Forsterite Bioceramic on in Vitro Activity and Antibacterial Properties of Bioactive Glass-Forsterite Nanocomposite Powders, Advanced Powder Technology (2016)
50. Preparation and Characterization of Aligned Porous Pcl/Zein Scaffolds As Drug Delivery Systems Via Improved Unidirectional Freeze-Drying Method, Materials Science and Engineering C (2016)