Long Noncoding Rna-Mirna-Mrna Axes Multiple Roles in Osteosarcoma

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):

Share By

Long Noncoding Rna-Mirna-Mrna Axes Multiple Roles in Osteosarcoma Publisher

Malakoti F^{1, 2} ; Alemi F¹ ; Karimzadeh H³ ; Asemi Z⁴ ; Asadi M⁵ ; Ghobadi H¹ ; Soleimanpour J⁶ ; Yousefi B¹

Source: Gene Reports Published:2021

Abstract

Osteosarcoma is the most predominant primary bone malignant tumor in adolescents, characterized by high tumor mortality and poor treatment ratio. Long noncoding RNAs (lncRNAs) have important roles in key cell biological events encompassing differentiation, proliferation, development, invasion, and migration which accomplish this task by regulating genome functions including transcription, splicing, and epigenetics. Besides, some lncRNAs have been recently connected with the emergence of malignancy, and also important events involved in the cancer treatment process, such as drug sensitivity and resistance. In this article, we reviewed the effects of lncRNAs on osteosarcoma cells progression, prognosis, and drug resistance by modulating miRNAs and signaling pathways. © 2021 Elsevier Inc.

Related Docs

View other Related Docs

1. Multiple Function of Lncrna Malat1 in Cancer Occurrence and Progression, Chemical Biology and Drug Design (2023)

2. Competing Endogenous Rnas Regulatory Crosstalk Networks: The Messages From the Rna World to Signaling Pathways Directing Cancer Stem Cell Development, Heliyon (2024)

3. Singe Nucleotide Polymorphisms in Osteosarcoma: Pathogenic Effect and Prognostic Significance, Experimental and Molecular Pathology (2019)

Experts (# of related papers)

View all Related Experts

Mohammadreza Sharifi (2)

Majid Ghanavat (1)

Other Related Docs

4. Potential Roles of Lncrna-Xist/Mirnas/Mrnas in Human Cancer Cells, Clinical and Translational Oncology (2023)

5. Modulation of Long Non-Coding Rnas and Micrornas by Quercetin As a Potential Therapeutical Approach in Cancer: A Comprehensive Review, Current medicinal chemistry (2025)

6. Exploring Potential Roles of Long Non-Coding Rnas in Cancer Immunotherapy: A Comprehensive Review, Frontiers in Immunology (2024)

7. A Comprehensive Review of the Role of Lncrnas in Gastric Cancer (Gc) Pathogenesis, Immune Regulation, and Their Clinical Applications, Pathology Research and Practice (2023)

8. The Expression of Mir-181B, Cyld, Cbx-7, Bcl2, and P53 in Osteosarcoma Patients and Correlation With Clinicopathological Factors, Chemical Biology and Drug Design (2023)

9. Role of Non-Coding Rnas in Osteoporosis, Pathology Research and Practice (2024)

10. The Importance of the Circrna/Wnt Axis in Gliomas: Biological Functions and Clinical Opportunities, Pathology Research and Practice (2024)

11. The Pathogenic Roles of Lncrna-Taurine Upregulated 1 (Tug1) in Colorectal Cancer, Cancer Cell International (2022)

12. Induction of Apoptosis and Necrosis in Human Acute Erythroleukemia Cells by Inhibition of 47Tlong Non-Coding Rna Pvt1, Molecular Biology Research Communications (2018)

13. Cross-Talk Between Oxidative Stress Signaling and Microrna Regulatory Systems in Carcinogenesis: Focused on Gastrointestinal Cancers, Biomedicine and Pharmacotherapy (2020)

14. Interplays Between Non-Coding Rnas and Chemokines in Digestive System Cancers, Biomedicine and Pharmacotherapy (2022)

15. Exploring the Dual Role of Malat1 in Thyroid Tumorigenesis: Oncogenic or Tumor Suppressor?, Current Molecular Medicine (2025)

16. Non-Coding Rnas in Leukemia Drug Resistance: New Perspectives on Molecular Mechanisms and Signaling Pathways, Annals of Hematology (2024)

17. Microrna in Leukemia: Tumor Suppressors and Oncogenes With Prognostic Potential, Journal of Cellular Physiology (2019)

18. Mir-1236: Key Controller of Tumor Development and Progression: Focus on the Biological Functions and Molecular Mechanisms, Pathology Research and Practice (2023)

19. A Pan-Cancer Analysis Indicates Long Noncoding Rna Hand2-As1 As a Potential Prognostic, Immunomodulatory and Therapeutic Biomarker in Various Cancers Including Colorectal Adenocarcinoma, Cancer Cell International (2023)

20. Molecular Mechanisms of Drug Resistance in Ovarian Cancer, Journal of Cellular Physiology (2018)

Style	Citing Format
MLA	Malakoti F, et al.. "Long Noncoding Rna-Mirna-Mrna Axes Multiple Roles in Osteosarcoma." Gene Reports, vol. 23, no. , 2021, pp. -.
APA	Malakoti F, Alemi F, Karimzadeh H, Asemi Z, Asadi M, Ghobadi H, Soleimanpour J, Yousefi B (2021). Long Noncoding Rna-Mirna-Mrna Axes Multiple Roles in Osteosarcoma. Gene Reports, 23(), -.
Chicago	Malakoti F, Alemi F, Karimzadeh H, Asemi Z, Asadi M, Ghobadi H, Soleimanpour J, Yousefi B. "Long Noncoding Rna-Mirna-Mrna Axes Multiple Roles in Osteosarcoma." Gene Reports 23, no. (2021): -.
Harvard	Malakoti F et al. (2021) 'Long Noncoding Rna-Mirna-Mrna Axes Multiple Roles in Osteosarcoma', Gene Reports, 23(), pp. -.
Vancouver	Malakoti F, Alemi F, Karimzadeh H, Asemi Z, Asadi M, Ghobadi H, et al.. Long Noncoding Rna-Mirna-Mrna Axes Multiple Roles in Osteosarcoma. Gene Reports. 2021;23():-.
BibTex	@article{ author = {Malakoti F and Alemi F and Karimzadeh H and Asemi Z and Asadi M and Ghobadi H and Soleimanpour J and Yousefi B}, title = {Long Noncoding Rna-Mirna-Mrna Axes Multiple Roles in Osteosarcoma}, journal = {Gene Reports}, volume = {23}, number = {}, pages = {-}, year = {2021} }
RIS	TY - JOUR AU - Malakoti F AU - Alemi F AU - Karimzadeh H AU - Asemi Z AU - Asadi M AU - Ghobadi H AU - Soleimanpour J AU - Yousefi B TI - Long Noncoding Rna-Mirna-Mrna Axes Multiple Roles in Osteosarcoma JO - Gene Reports VL - 23 IS - SP - EP - PY - 2021 ER -

Science Communicator Platform

Authors

Abstract