Association Between Dietary Intake of Fatty Acids and Colorectal Cancer, a Case-Control Study

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Association Between Dietary Intake of Fatty Acids and Colorectal Cancer, a Case-Control Study Publisher

Shekari S¹ ; Fathi S² ; Roumi Z³ ; Akbari ME⁴ ; Tajadod S⁵ ; Afsharfar M⁶ ; Hasanpour Ardekanizadeh N⁷ ; Bourbour F⁸ ; Keshavarz SA⁹ ; Sotoudeh M¹ ; Gholamalizadeh M⁴ ; Nemat Gorgani S¹⁰ ; Shafaei Kachaei H¹¹ ; Alizadeh A¹² Show All Authors

Shekari S¹
Fathi S²
Roumi Z³
Akbari ME⁴
Tajadod S⁵
Afsharfar M⁶
Hasanpour Ardekanizadeh N⁷
Bourbour F⁸
Keshavarz SA⁹
Sotoudeh M¹
Gholamalizadeh M⁴
Nemat Gorgani S¹⁰
Shafaei Kachaei H¹¹
Alizadeh A¹²
Doaei S¹³

Source: Frontiers in Nutrition Published:2022

Abstract

Background: The association of dietary fat and colorectal cancer (CRC) was frequently reported. However, few studies assessed the effects of different types of dietary fats on CRC. This study aimed to investigate the association between intakes of different types of dietary fatty acids with colorectal cancer risk. Methods: This case-control study was conducted on 480 participants including 160 CRC cases and 320 healthy controls in Firoozgar Hospital, Tehran, Iran. The intake of dietary fatty acids of the participants was assessed using a semi quantitative food frequency questionnaire (FFQ). Results: The mean intake of cholesterol (273.07 ± 53.63 vs. 254.17 ± 61.12, P = 0.001), polyunsaturated fatty acids (PUFA) (16.54 ± 4.20 vs. 15.41 ± 4.44, P = 0.012), and calorie (2,568.76 ± 404.48 vs. 2,493.38 ± 176.03, P = 0.006) was higher and the mean intake of oleic acid (5.59 ± 3.17 vs. 8.21 ± 5.46) and linoleic acid (6.03 ± 3.44 vs. 7.02 ± 4.08, P = 0.01) was lower in the case group compared to the control group. An inverse association was found between colorectal cancer (CRC) and dietary intake of oleic acid (OR: 0.85, CI 95% 0.80–0.90, P = 0.001), linoleic acid (OR: 0.85, CI 95% 0.78–0.93, P = 0.001), and α-linolenic acid (OR: 0.75, CI 95% 0.57–0.98, P = 0.04). The association remained significant after adjusting for age and sex, sleep, smoking, and alcohol consumption, and BMI. Conclusions: The results of this study support a protective effect of oleic acid, linoleic acid, and α-linolenic acid against CRC. Further longitudinal studies are warranted to confirm these results. Copyright © 2022 Shekari, Fathi, Roumi, Akbari, Tajadod, Afsharfar, Hasanpour Ardekanizadeh, Bourbour, Keshavarz, Sotoudeh, Gholamalizadeh, Nemat Gorgani, Shafaei Kachaei, Alizadeh and Doaei.

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Style	Citing Format
MLA	Shekari S, et al.. "Association Between Dietary Intake of Fatty Acids and Colorectal Cancer, a Case-Control Study." Frontiers in Nutrition, vol. 9, no. , 2022, pp. -.
APA	Shekari S, Fathi S, Roumi Z, Akbari ME, Tajadod S, Afsharfar M, Hasanpour Ardekanizadeh N, Bourbour F, Keshavarz SA, Sotoudeh M, Gholamalizadeh M, Nemat Gorgani S, Shafaei Kachaei H, Alizadeh A, Doaei S (2022). Association Between Dietary Intake of Fatty Acids and Colorectal Cancer, a Case-Control Study. Frontiers in Nutrition, 9(), -.
Chicago	Shekari S, Fathi S, Roumi Z, Akbari ME, Tajadod S, Afsharfar M, Hasanpour Ardekanizadeh N, et al.. "Association Between Dietary Intake of Fatty Acids and Colorectal Cancer, a Case-Control Study." Frontiers in Nutrition 9, no. (2022): -.
Harvard	Shekari S et al. (2022) 'Association Between Dietary Intake of Fatty Acids and Colorectal Cancer, a Case-Control Study', Frontiers in Nutrition, 9(), pp. -.
Vancouver	Shekari S, Fathi S, Roumi Z, Akbari ME, Tajadod S, Afsharfar M, et al.. Association Between Dietary Intake of Fatty Acids and Colorectal Cancer, a Case-Control Study. Frontiers in Nutrition. 2022;9():-.
BibTex	@article{ author = {Shekari S and Fathi S and Roumi Z and Akbari ME and Tajadod S and Afsharfar M and Hasanpour Ardekanizadeh N and Bourbour F and Keshavarz SA and Sotoudeh M and Gholamalizadeh M and Nemat Gorgani S and Shafaei Kachaei H and Alizadeh A and Doaei S}, title = {Association Between Dietary Intake of Fatty Acids and Colorectal Cancer, a Case-Control Study}, journal = {Frontiers in Nutrition}, volume = {9}, number = {}, pages = {-}, year = {2022} }
RIS	TY - JOUR AU - Shekari S AU - Fathi S AU - Roumi Z AU - Akbari ME AU - Tajadod S AU - Afsharfar M AU - Hasanpour Ardekanizadeh N AU - Bourbour F AU - Keshavarz SA AU - Sotoudeh M AU - Gholamalizadeh M AU - Nemat Gorgani S AU - Shafaei Kachaei H AU - Alizadeh A AU - Doaei S TI - Association Between Dietary Intake of Fatty Acids and Colorectal Cancer, a Case-Control Study JO - Frontiers in Nutrition VL - 9 IS - SP - EP - PY - 2022 ER -