Isfahan University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Evaluation and Comparison of Target and At-Risk Organ Dosimetry in Radiation Therapy of Prostate Cancer Patients Using Three-Dimensional Conformal Radiotherapy (3D-Crt) and Intensity-Modulated Radiation Therapy (Imrt) Publisher



Bagheri H1 ; Tavakoli MB1 ; Abedi I1 ; Amouheidari A2
Authors
Show Affiliations
Authors Affiliations
  1. 1. Department of Medical Physics, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
  2. 2. Department of Radiation-Oncology, Milad Hospital, Isfahan, Iran

Source: Journal of Isfahan Medical School Published:2022


Abstract

Background: The goal of this study was to make a dosimetric comparison between the absorbed dose distribution of the prostate and the organ at risk (OAR) using two different approaches: three-dimensional conformal radiotherapy (3D-CRT) and Intensity-modulated radiotherapy (IMRT), assesed via treatment planning system (TPS) and thermoluminescence dosimetry (TLD). Methods: In this study, 35 patients with prostate cancer undergoing radiation therapy at Milad Hospital in Isfahan were included. Prostate as target and rectum, bladder and femoral head as healthy organ at risk (OAR) were contoured according to Radiation Therapy Oncology Group (RTOG) criteria. Two separate dosimetry programs IMRT and 3D-CRT have been developed for each patient in order to evaluate the dosimetric status of both methods comparatively. These results were then compared with those of the phantom. Findings: The doses to the bladder, rectum, and femoral head were 50.3, 58.6, and 16.4 in IMRT and 59.6, 68.8, and 34.8 in 3D-CRT, respectively. The dose measured by TLD in all organs in the phantom was higher than the dose calculated by TPS software in the phantom. Conclusion: The IMRT method is a better method than 3D-CRT due to better coverage of the target volume and reduction of the cumulative dose of organs at risk (OAR). The dose measured by TLDs was higher than the dose calculated by the treatment planning system, which may be due to the fact that the treatment planning system does not calculate the share of scattered radiation in the absorbed dose of organs. © 2022 Isfahan University of Medical Sciences(IUMS). All rights reserved.
Related Docs
View other Related Docs
1. Dosimetric and Radiobiological Evaluation of Multiparametric Mri-Guided Dose Painting in Radiotherapy of Prostate Cancer, Journal of Medical Signals and Sensors (2017)
2. Comparison of Conventional Radiotherapy Techniques With Different Energies in Treating Prostate Cancer, Employing a Designed Pelvis Phantom, Journal of Medical Sciences (2008)
3. Evaluation of Targeted Image-Guided Radiation Therapy Treatment Planning System by Use of American Association of Physicists in Medicine Task Group-119 Test Cases, Journal of Medical Signals and Sensors (2018)
4. Evaluation of the Effects of Prostate Radiation Therapy on Occludin Expression and Ultrasonography Characteristics of the Bladder, International Journal of Radiation Oncology Biology Physics (2017)
5. The Comparison of Radiation Dosimetry of Rectal Cancer in Two Supine and Prone Positions, Journal of Isfahan Medical School (2023)
6. Development and Validation of Mcnpx-Based Monte Carlo Treatment Plan Verification System, Journal of Medical Physics (2015)
7. Evaluation of the Lung Dose in Three-Dimensional Conformal Radiation Therapy of Left-Sided Breast Cancer: A Phantom Study, Journal of Medical Signals and Sensors (2020)
8. Dosiomics-Based Detection of Dose Distribution Variations in Helical Tomotherapy for Prostate Cancer Patients: Influence of Treatment Plan Parameters, Physical and Engineering Sciences in Medicine (2024)
Experts (# of related papers)
View all Related Experts
Daryoush Shahbazi-Gahrouei (29)
Ahmad Shanei (20)
Other Related Docs
9. Development and Implementation of a Monte Carlo Frame Work for Evaluation of Patient Specific Out- of - Field Organ Equivalent Dose, International Journal of Radiation Research (2017)
10. Comparison of Organs at Risk Dose in Conventional (2-Dimensional) and Conformal (3-Dimensional) Radiotherapy of Seminoma, Journal of Isfahan Medical School (2018)
11. Comparison of 3D Conformal and Intensity Modulated Radiotherapy in Early Stage Oral Tongue Cancer: Dosimetric and Radiobiological Evaluation, International Journal of Radiation Research (2020)
12. Evaluation of Error Doses of Treatment Planning Software Using Solid Anthropomorphic Phantom, Journal of Isfahan Medical School (2016)
13. Dosimetric Comparison of Treatment of Left Breast Cancer Using 3-Dimention Conformal Radiotherapy Technique and Tomotherapy, Journal of Isfahan Medical School (2022)
14. Monte Carlo Evaluation of Out-Of-Field Dose in 18 Mv Pelvic Radiotherapy Using a Simplified Female Mird Phantom, Biomedical Physics and Engineering Express (2022)
15. Evaluation of Bone Marrow Absorbed Dose of 153Sm-Edtmp and 223Ra-Cl2 in Patients With Bone Metastasis Using Monte Carlo Simulation, Journal of Isfahan Medical School (2021)
16. Dosimetric Characteristics of Tomotherapy and Three-Dimensional Conformal Radiotherapy for Head and Neck Cancer, International Journal of Radiation Research (2023)
17. The Average of Cumulative Radiation Dose in Neonates in the Neonatal Surgery Ward Due to Diagnostic and Therapeutic Radiologic Procedures During the Admission Period, Journal of Isfahan Medical School (2011)
18. Dosimetric Comparison of Treatment of Left Breast Cancer Using 3-Dimention Conformal Radiotherapy Technique (3D-Crt) and Intensity-Modulated Radiotherapy Technique (Imrt), Journal of Isfahan Medical School (2018)
19. Dosimetric Verification of Lung Phantom Calculated by Collapsed Cone Convolution: A Monte Carlo and Experimental Evaluation, Journal of X-Ray Science and Technology (2019)
20. Estimating Radiotherapy-Induced Secondary Cancer Risk Arising From Brain Irradiation at High Energy: A Monte Carlo Study, Frontiers in Biomedical Technologies (2022)
21. Measurement of Imposed Radiation Dose and Normal Tissue Complications Probability to Lung and Heart in Patients With Mastectomy Using Two Common Tangential Radiotherapy Methods of Supraclavicular Nodes, Anterior-Posterior (Ap) and Two Parallel Opposed Fields (Pofs), Journal of Isfahan Medical School (2018)
22. Dosimetric Comparison of Two Methods of Three-Dimensional Conformal Radiotherapy and Helical Tomotherapy in Head and Neck Cancer Patients With Involvement of Regional Lymph Nodes, Journal of Isfahan Medical School (2023)
23. Determination of Uterus Absorbed Dose by Patients Following Myocardial Perfusion Scan Using Tld and Conjugate View Methods, Journal of Biomedical Physics and Engineering (2019)
24. Entrance Surface Dose Measurements for Routine X-Ray Examinations in Chaharmahal and Bakhtiari Hospitals, Iranian Journal of Radiation Research (2006)
25. Secondary Cancer Risk After Radiotherapy of Seminoma Stage One, Iranian Journal of Medical Physics (2022)
26. Investigation of the Absorbed Dose and Estimation of the Risk of Secondary Thyroid Cancer in Whole-Brain Radiotherapy, Journal of Isfahan Medical School (2017)
27. Nested Cnn Architecture for Three-Dimensional Dose Distribution Prediction in Tomotherapy for Prostate Cancer, Strahlentherapie und Onkologie (2025)
28. Estimating the Absorbed Doses From 99Mtc-Mdp in Patients Following Bone Scan, Journal of Isfahan Medical School (2015)
29. Radiobiological Evaluation and Comparison of Treatment Plans in Two Methods of 3D Adaptive Radiation Therapy and Tomotherapy for Left Pendular Breast Cancer and the Risk of Pericarditis and Pneumonia; [ارزیابی و مقایسهی رادیوبیولوژیکی طرحهای درمان در دو روش پرتودرمانی تطبیقی سه بعدی و توموتراپی], Journal of Isfahan Medical School (2023)
30. Evaluation of the Photon Dose Calculation Accuracy in Radiation Therapy of Malignant Pleural Mesothelioma, Journal of Cancer Research and Therapeutics (2018)
31. Occupational Radiation Exposure in Anesthesia Personal From C-Arm Fluoroscopy During Orthopedic Surgical Procedures, Journal of Isfahan Medical School (2016)
32. Evaluation of the Lung Volume Changes in Patients With Breast Cancer Based on the Received Dose in the Upper and Lower Lobes of the Lung, Journal of Isfahan Medical School (2019)
33. Diagnostic Reference Levels (Drls) for Routine X-Ray Examinations in Lorestan Province, Iran, International Journal of Radiation Research (2015)
34. Estimation of Cell Response in Fractionation Radiotherapy Using Different Methods Derived From Linear Quadratic Model, Radiology and Oncology (2015)
35. A Comparison of Selected Dosimetric Parameters of Two Hodgkin Lymphoma Radiotherapy Techniques With Reference to Potential Risk of Radiation Induced Heart Disease, Polish Journal of Medical Physics and Engineering (2018)
36. Patient Dose Resulting From Ct Examinations in Yazd, Iran, Iranian Journal of Radiation Research (2006)
37. Optimization of Ct Slice Thickness in 3D-Crt and Imrt Planning of Low Grade Glioma, International Journal of Radiation Research (2021)
38. Predictors of Bone Metastasis in Pre-Treatment Staging of Asymptomatic Treatment-Naive Patients With Prostate Cancer, Revista Espanola de Medicina Nuclear e Imagen Molecular (2013)
39. Development and Implementation of the Convolution Method for Photon Dose Calculation in Radiation Therapy, Journal of Isfahan Medical School (2012)
40. Comparison of the Radiation Dose Absorbed to the Testes of Men Undergoing Pelvis Radiotherapy for Cancer, Journal of Isfahan Medical School (2007)
41. Monte Carlo Study of Fetal Dosimetry Parameters for 6 Mv Photon Beam, Journal of Medical Signals and Sensors (2013)
42. Radiomics Based Predictive Modeling of Rectal Toxicity in Prostate Cancer Patients Undergoing Radiotherapy: Ct and Mri Comparison, Physical and Engineering Sciences in Medicine (2023)
43. Evaluation of a Treatment Planning System for Applying the Effect of Titanium Clips on Isodosedistribution in Radiation Therapy of Colorectal Cancer, Journal of Isfahan Medical School (2017)
44. Dosimetric Comparison of Treatment of Left Breast Cancer Using Two Different Dose Schedules, Tehran University Medical Journal (2020)
45. Comparison of Dosimetry of Organs at Risk for the Treatment of Nasopharyngeal Cancer Using Two Methods of Helical Tomotherapy and Three Dimensional Conformal Radiation Therapy, Journal of Isfahan Medical School (2023)
46. Evaluation of the Changes in the Shape and Location of the Prostate and Pelvic Organs Due to Bladder Filling and Rectal Distension, Iranian Red Crescent Medical Journal (2011)
47. Effect of Hypofractionation on Prostate Cancer Radiotherapy, International Journal of Cancer Management (2017)
48. Determination of the Neutron Contamination During Brain Radiotherapy Using a Moderated-Boron Trifluoride Detector and the Mcnp Monte Carlo Code, Radiation Protection Dosimetry (2022)
49. Evaluation of Risk of Secondary Thyroid Cancer Caused by Neutron Dose Equivalent From Brain Tumor 3D-Conformal Radiation Therapy (3D-Crt), Journal of Isfahan Medical School (2020)
50. Radiobiological Comparison of 3D Conformal and Intensity Modulated Radiation Therapy in the Treatment of Left-Sided Breast Cancer, International Journal of Radiation Research (2020)