Isfahan University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
A Spatially Explicit Agent-Based Simulation Model of a Reservoir Host of Cutaneous Leishmaniasis, Rhombomys Opimus Publisher



Rajabi M1 ; Mansourian A1 ; Pilesjo P1 ; Shirzadi MR2 ; Fadaei R3 ; Ramazanpour J4
Authors
Show Affiliations
Authors Affiliations
  1. 1. GIS Center, Department of Physical Geography and Ecosystem Science, Lund University, Sweden
  2. 2. Zoonoses Control Department, Center for Communicable Diseases Control, Ministry of Health, Iran
  3. 3. Infectious Diseases and Tropical Medicine Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
  4. 4. Isfahan Health Center, Isfahan University of Medical Sciences, Isfahan, Iran

Source: Ecological Modelling Published:2018


Abstract

Rhombomys opimus (R. opimus), a social rodent, is the main reservoir host for zoonotic cutaneous leishmaniasis (ZCL) in most parts of the Middle East and central Asia. The difficulties in monitoring rodent population patterns have hindered the effective application of preventive measures of ZCL. This study presents a spatially explicit agent-based simulation model of R. opimus behaviors that is integrated with Geographic Automata System (GAS) and a heuristic optimization method, cuckoo search (CS). The model is used to explore the relationships among rodent population dynamics, ZCL incidence and authority interventions using statistical data generated from simulated rodent societies rather than observational data, which are difficult to obtain through field surveys. The model simulation considers three agent types: rodents, colonies and cell agents. The model components and overall approach are calibrated, investigated with sensitivity analysis and validated with empirical field data in a ZCL-endemic area in Isfahan, central Iran. The results suggest that unsupervised and sporadic preventive measures could cause rodent emigration towards human population centers and start new waves of infections. © 2017 Elsevier B.V.
Related Docs
View other Related Docs
1. A Spatially Explicit Agent-Based Modeling Approach for the Spread of Cutaneous Leishmaniasis Disease in Central Iran, Isfahan, Environmental Modelling and Software (2016)
2. Climate Change and Distribution of Zoonotic Cutaneous Leishmaniasis (Zcl) Reservoir and Vector Species in Central Iran, Modeling Earth Systems and Environment (2021)
3. Identification of Leishmania Isolates From Healing and Nonhealing Cutaneous Leishmaniasis Patients Using Internal Transcribed Spacer Region Pcr, Jundishapur Journal of Microbiology (2014)
4. Cutaneous Leishmaniasis Reinfection: Skin Disease and Leishmaniasis Research Center, Isfahan, Iran, Journal of Isfahan Medical School (2015)
5. Aerobic Bacterial Flora of Biotic and Abiotic Compartments of a Hyperendemic Zoonotic Cutaneous Leishmaniasis (Zcl) Focus, Parasites and Vectors (2015)
6. Molecular Epidemiological Survey of Cutaneous Leishmaniasis in Two Highly Endemic Metropolises of Iran, Application of Fta Cards for Dna Extraction From Giemsa-Stained Slides, Jundishapur Journal of Microbiology (2016)
7. Gis-Based Risk Mapping of Cutaneous Leishmaniasis: A Survey in an Endemic Area of Central Iran, Environmental Science and Pollution Research (2021)
8. An Outbreak of Cutaneous Leishmaniasis Due to Leishmania Major in an Endemic Focus in Central Iran, Journal of Parasitic Diseases (2022)
Experts (# of related papers)
View all Related Experts
Seyed Hossein Hejazi (4)
Seyed Hossein Mirhendi Esfahani (2)
Other Related Docs
9. Bacterial Superinfection in Zoonotic Cutaneous Leishmaniasis, Medical Science Monitor (2012)
10. Clinical Assessment of Novel Nanofibrous Dressings for Cutaneous Leishmaniasis: A Trial-Based Study, Polymers for Advanced Technologies (2024)
11. Leishmania Spp. Infection in Rhombomys Opimus and Meriones Libycus As Main Reservoirs of Zoonotic Cutaneous Leishmaniasis in Central Parts of Iran: Progress and Implications in Health Policy, Acta Tropica (2022)
12. Sandfly Fauna in an Endemic Focus for Cutaneous Leishmaniasis in Dezful District, Iran (2018-2019), Journal of Isfahan Medical School (2020)
13. The Cutaneous Leishmaniasis Reservoirs in Northern Baraan Region of Isfahan, Iran, Journal of Isfahan Medical School (2013)
14. Rodenticide Comparative Effect of Klerat® and Zinc Phosphide for Controlling Zoonotic Cutaneous Leishmaniasis in Central Iran, Iranian Journal of Parasitology (2016)
15. Genetic Analysis of Clinical Isolates of Leishmania Major From Isfahan, Iran, Journal of Vector Borne Diseases (2012)
16. Comparative Study on the Effectiveness of Coumavec® and Zinc Phosphide in Controlling Zoonotic Cutaneous Leishmaniasis in a Hyperendemic Focus in Central Iran, Journal of Arthropod-Borne Diseases (2012)
17. Emerging of Cutaneous Leishmaniais Due to Leishmania Major in a New Focus in Esfahan Province, Central Iran, Journal of Arthropod-Borne Diseases (2020)
18. Domestic and Peridomestic Risk Factors Associated With Transmission of Cutaneous Leishmaniasis in Three Hypo Endemic, Endemic, and Hyper Endemic Areas: A Randomized Epidemiological Study, Journal of Research in Medical Sciences (2014)
19. Genetic Diversity of Leishmania Major Strains Isolated From Phlebotomus Papatasi and Phlebotomus Alexandri in Western Iran Based on Minicircle Kdna, Journal of Parasitic Diseases (2021)