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The Beneficial Effects of Psyllium on Cardiovascular Diseases and Their Risk Factors: Systematic Review and Dose-Response Meta-Analysis of Randomized Controlled Trials Publisher



Gholami Z1, 2 ; Paknahad Z3
Authors
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Authors Affiliations
  1. 1. School of Nutrition and Food Science, Students' Research Committee, Isfahan University of Medical Sciences, Isfahan, Iran
  2. 2. Department of Clinical Nutrition, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran
  3. 3. Department of Clinical Nutrition, Faculty of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran

Source: Journal of Functional Foods Published:2023


Abstract

The aim of this systematic review and dose-response meta-analysis is to investigate the impact of psyllium on cardiovascular risk factors. From 2022 to 2023, we searched ISI Web of Science (WOS), PubMed, and Scopus for related publications, including randomized controlled trials (RCT) evaluating the effect of psyllium on cardiovascular risk factors in adults. Psyllium significantly decreased Homeostatic Model Assessment of Insulin Resistance (HOMA IR): (WMD: −1.17; 95% CI: −2.11, −0.23; p < 0.05), hemoglobin A1C (HbA1c): (WMD: −0.75; 95% CI: −1.21, −0.29; p < 0.001), systolic blood pressure (SBP): (WMD): −2.24; 95% CI: −3.13, −1.35; p < 0.05), fasting blood sugar (FBS): (WMD: −6.89; 95% CI: −10.62, −3.16; p < 0.001), Total cholesterol: (WMD): −9.05; 95% CI: −13.71, −4.40; p < 0.05) and low-density lipoprotein cholesterol (LDL_C): (WMD: −8.55; 95% CI: −12.92, −4.19; p < 0.0001), and increased weight: (WMD: 3.57; 95% CI: 1.43, 5.72; p < 0.05). © 2023
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