Isfahan University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share By
Association of Estimated Sleep Duration and Naps With Mortality and Cardiovascular Events: A Study of 116 632 People From 21 Countries Publisher Pubmed



Wang C1, 2 ; Bangdiwala SI1 ; Rangarajan S1 ; Lear SA3 ; Alhabib KF4 ; Mohan V5 ; Teo K1 ; Poirier P6 ; Tse LAH7 ; Liu Z7 ; Rosengren A8 ; Kumar R9 ; Lopezjaramillo P10 ; Yusoff K11, 12 Show All Authors
Authors
  1. Wang C1, 2
  2. Bangdiwala SI1
  3. Rangarajan S1
  4. Lear SA3
  5. Alhabib KF4
  6. Mohan V5
  7. Teo K1
  8. Poirier P6
  9. Tse LAH7
  10. Liu Z7
  11. Rosengren A8
  12. Kumar R9
  13. Lopezjaramillo P10
  14. Yusoff K11, 12
  15. Monsef N13
  16. Krishnapillai V14
  17. Ismail N15
  18. Seron P16
  19. Dans AL17
  20. Kruger L18
  21. Yeates K19
  22. Leach L20
  23. Yusuf R21
  24. Orlandini A22
  25. Wolyniec M23
  26. Bahonar A24
  27. Mohan I25
  28. Khatib R26
  29. Temizhan A27
  30. Li W2
  31. Yusuf S1

Source: European Heart Journal Published:2019


Abstract

Aims To investigate the association of estimated total daily sleep duration and daytime nap duration with deaths and major cardiovascular events. Methods We estimated the durations of total daily sleep and daytime naps based on the amount of time in bed and self- and results reported napping time and examined the associations between them and the composite outcome of deaths and major cardiovascular events in 116 632 participants from seven regions. After a median follow-up of 7.8 years, we recorded 4381 deaths and 4365 major cardiovascular events. It showed both shorter (<_6 h/day) and longer (>8 h/day) estimated total sleep durations were associated with an increased risk of the composite outcome when adjusted for age and sex. After adjustment for demographic characteristics, lifestyle behaviours and health status, a J-shaped association was observed. Compared with sleeping 6–8 h/day, those who slept <_6 h/day had a non-significant trend for increased risk of the composite outcome [hazard ratio (HR), 1.09; 95% confidence interval, 0.99–1.20]. As estimated sleep duration increased, we also noticed a significant trend for a greater risk of the composite outcome [HR of 1.05 (0.99–1.12), 1.17 (1.09–1.25), and 1.41 (1.30–1.53) for 8–9 h/day, 9–10 h/day, and >10 h/day, Ptrend < 0.0001, respectively]. The results were similar for each of all-cause mortality and major cardiovascular events. Daytime nap duration was associated with an increased risk of the composite events in those with over 6 h of nocturnal sleep duration, but not in shorter nocturnal sleepers (<_6 h). Conclusion Estimated total sleep duration of 6–8 h per day is associated with the lowest risk of deaths and major cardiovascular events. Daytime napping is associated with increased risks of major cardiovascular events and deaths in those with >6 h of nighttime sleep but not in those sleeping <_6 h/night. © The Author(s) 2019. Published on behalf of the European Society of Cardiology. All rights reserved. VC The Author(s) 2018.
Other Related Docs