Postoperative Pain of Single-Visit Endodontic Treatment With Gutta-Percha Versus Mta Filling: A Randomized Superiority Trial Publisher Pubmed



Khabiri M¹ ; Kamgar S² ; Iranmanesh P³ ; Khademi A^{3, 5} ; Torabinejad M⁴
Source: BMC Oral Health Published:2023

Abstract

Background: Postoperative pain has remained a challenge for clinicians. This randomized superiority trial compared the levels of postoperative pain following the use of gutta-percha (GP) and sealer or mineral trioxide aggregate (MTA) as root canal filling materials in teeth with asymptomatic apical periodontitis. Methods: A total of 119 patients were initially evaluated in this two-arm, parallel-group, single-blind, superiority randomized trial. The inclusion criteria were participants aged 18–65 years with single-canal premolars diagnosed with asymptomatic apical periodontitis. The participants were finally divided into two groups using the permuted block randomization method. In the GP group (N = 46), the cleaned and shaped root canals were filled with gutta-percha and AH Plus sealer, while in the MTA group (N = 48), the cleaned and shaped root canals were filled with an MTA apical filling and a coronal gutta-percha and sealer. Patient pain level was measured 6, 12, 24, 48, and 72 h postoperatively using a 10-point visual analog scale (VAS). The data were analyzed by the chi-square, independent t, Friedman, and Mann-Whitney U tests. Results: The mean of VAS scores decreased significantly over time in both groups (P < 0.001). The mean VAS scores were significantly lower in the MTA filling group than in the other group (P < 0.05). Female patients reported higher VAS scores at 6- and 12-hour periods in both groups (P < 0.05). Conclusion: MTA as a root canal filling material might be a valuable option for clinicians due to its low postoperative pain. Trial registration: The trial protocol was registered at the Registry of Clinical Trials (IRCT20191104045331N1). © 2023, The Author(s).