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Postoperative Pain of Single-Visit Endodontic Treatment With Gutta-Percha Versus Mta Filling: A Randomized Superiority Trial Publisher Pubmed



Khabiri M1 ; Kamgar S2 ; Iranmanesh P3 ; Khademi A3, 5 ; Torabinejad M4
Authors
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Authors Affiliations
  1. 1. Department of Endodontics, Faculty of Dentistry, Isfahan (Khorasgan) Branch, Islamic Azad University, Isfahan, Iran
  2. 2. Department of Endodontics, Isfahan (Khorasgan) Branch, Islamic Azad University, Isfahan, Iran
  3. 3. Department of Endodontics, Dental Research Center, Dental Research Institute, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran
  4. 4. School of Dentistry, Loma Linda University, Loma Linda, CA, United States
  5. 5. School of Dentistry, Isfahan University of Medical Sciences, Hezar-Jerib Ave, Isfahan, 81746-73461, Iran

Source: BMC Oral Health Published:2023


Abstract

Background: Postoperative pain has remained a challenge for clinicians. This randomized superiority trial compared the levels of postoperative pain following the use of gutta-percha (GP) and sealer or mineral trioxide aggregate (MTA) as root canal filling materials in teeth with asymptomatic apical periodontitis. Methods: A total of 119 patients were initially evaluated in this two-arm, parallel-group, single-blind, superiority randomized trial. The inclusion criteria were participants aged 18–65 years with single-canal premolars diagnosed with asymptomatic apical periodontitis. The participants were finally divided into two groups using the permuted block randomization method. In the GP group (N = 46), the cleaned and shaped root canals were filled with gutta-percha and AH Plus sealer, while in the MTA group (N = 48), the cleaned and shaped root canals were filled with an MTA apical filling and a coronal gutta-percha and sealer. Patient pain level was measured 6, 12, 24, 48, and 72 h postoperatively using a 10-point visual analog scale (VAS). The data were analyzed by the chi-square, independent t, Friedman, and Mann-Whitney U tests. Results: The mean of VAS scores decreased significantly over time in both groups (P < 0.001). The mean VAS scores were significantly lower in the MTA filling group than in the other group (P < 0.05). Female patients reported higher VAS scores at 6- and 12-hour periods in both groups (P < 0.05). Conclusion: MTA as a root canal filling material might be a valuable option for clinicians due to its low postoperative pain. Trial registration: The trial protocol was registered at the Registry of Clinical Trials (IRCT20191104045331N1). © 2023, The Author(s).
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