Isfahan University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
The Effect of Using Articaine Versus Lidocaine for Inferior Alveolar Nerve Block on Pain After Root Canal Treatment: A Prospective, Randomized Clinical Study Publisher



Ghazalgoo A1 ; Saatchi M1 ; Khazaei S1, 3 ; Shadmehr E2
Authors
Show Affiliations
Authors Affiliations
  1. 1. Department of Endodontics, Dental Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
  2. 2. Devision of Endodontics, Preventive and Restorative Dental Sciences Department, University of California, San Francisco, CA, United States
  3. 3. Dental Research Center, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, 81746-73461, Iran

Source: Dental Hypotheses Published:2018


Abstract

Introduction: The control of pain associated with root canal treatment (RCT) is crucially important in endodontics. The aim of the present study was to compare the effect of using articaine versus lidocaine local anesthetics for inferior alveolar nerve block (IANB) on pain after RCT. Materials and Methods: Eighty-eight patients diagnosed with symptomatic irreversible pulpitis of a mandibular first molar were selected. The patients randomly received either a cartridge of lidocaine or articaine using IANB. RCT was initiated 15 min after the injection. Lip numbness was a requisite for all the patients. The post-operative pain was assessed by using 170-mm visual analog scale at 0, 2, 4, 6, 12, 18, 36, and 48 h after the treatment. The data were analyzed by SPSS 22 statistical software. Results: The mean total post-treatment pain in the lidocaine group was 37.1 ± 32.9 whereas it was 25.4 ± 26.4 for articaine group (P < 0.001). Pain at 4, 6, 12, 18, and 24 h after the RCT in articaine group was significantly less than the lidocaine group (P < 0.001). Conclusion: Using articaine for IANB may increase post-RCT comfort than lidocaine. Further study is needed to confirm the results. © 2019 Dental Hypotheses.
Related Docs
View other Related Docs
1. Effect of Back-Pressure Anesthesia on Postoperative Pain After the Endodontic Treatment in Patients With Symptomatic Irreversible Pulpitis: Randomized Double-Blind Clinical Trial, Journal of Endodontics (2024)
2. Preoperative Intraligamentary Injection of Dexamethasone Can Improve the Anesthetic Success Rate of 2% Lidocaine During the Endodontic Management of Mandibular Molars With Symptomatic Irreversible Pulpitis, Journal of Endodontics (2021)
3. Effect of Cooling of Lidocaine With Epinephrine on the Anesthetic Success of Supplementary Intraligamentary Injection After a Failed Primary Inferior Alveolar Nerve Block: A Randomized Controlled Trial, European Endodontic Journal (2023)
4. Effect of Premedication on the Success of Inferior Alveolar Nerve Block in Patients Diagnosed With Irreversible Pulpitis: An Umbrella Review, Dental Research Journal (2023)
5. Anesthetic Efficacy of Lidocaine/Ketorolac in Inferior Alveolar Nerve Block in Patients With Irreversible Pulpitis: A Randomized Clinical Trial, European endodontic journal (2020)
6. Effect of Magnesium Sulphate Added to Lidocaine on Inferior Alveolar Nerve Block Success in Patients With Symptoms of Irreversible Pulpitis: A Prospective, Randomized Clinical Trial, International Endodontic Journal (2020)
7. Anaesthetic Efficacy of 2% Lidocaine With Different Concentrations of Epinephrine (1:80,000 and 1:200,000) in Intraligamentary Injection After a Failed Primary Inferior Alveolar Nerve Block: A Randomized Double-Blind Study, Acta Odontologica Scandinavica (2020)
8. Anesthetic Efficacy of Articaine and Ketamine for Inferior Alveolar Nerve Block in Symptomatic Irreversible Pulpitis: A Prospective Randomized Double-Blind Study, Iranian Endodontic Journal (2017)
Experts (# of related papers)
View all Related Experts
Masoud Saatchi (25)
Abbasali Khademi (22)
Other Related Docs
9. The Effect of Adding Clonidine to Articaine and Epinephrine on Post-Treatment Pain: A Randomized Clinical Trial Study, Iranian Endodontic Journal (2021)
10. Association Between Psychological Factors and Pain Perception in Patients With Symptomatic Irreversible Pulpitis During Endodontic Treatment, Giornale Italiano di Endodonzia (2021)
11. Effect of Chlordiazepoxide and Oxazepam on the Success Rate of Mandibular Nerve Block Anesthesia: A Randomized Double Blind Control Trial, Advances in Environmental Biology (2014)
12. The Effects of Different Local Anesthetics on Hemodynamic After Injection for Endodontictherapy: A Randomized Clinical Trial, Acta Medica Mediterranea (2015)
13. Effect of Phentolamine As Reversal of Soft-Tissue Anesthesia on Post-Endodontic Pain in Patients With Symptomatic Irreversible Pulpitis: A Randomized Clinical Trial, Iranian Endodontic Journal (2019)
14. Effect of Sodium Bicarbonate Buccal Infiltration on the Success of Inferior Alveolar Nerve Block In Mandibular First Molars With Symptomatic Irreversible Pulpitis: A Prospective, Randomized Double-Blind Study, Journal of Endodontics (2016)
15. Postoperative Endodontic Pain of Three Different Instrumentation Techniques in Asymptomatic Necrotic Mandibular Molars With Periapical Lesion: A Prospective, Randomized, Double-Blind Clinical Trial, Clinical Oral Investigations (2017)
16. Articaine Buccal Infiltration for Mandibular First Molars With Symptomatic Irreversible Pulpitis: Is It As Effective As Inferior Alveolar Nerve Block With Lidocaine? a Systematic Review and Meta-Analysis, Clinical Oral Investigations (2025)
17. Effect of Preoperative Alprazolam on the Success of Inferior Alveolar Nerve Block for Teeth With Irreversible Pulpitis, Journal of Endodontics (2012)
18. Does a New Modification of the Two-Step Injection Technique for Inferior Alveolar Nerve Block Reduce Pain Compared to the Conventional Technique? a Randomized Clinical Trial, International Journal of Dentistry (2023)
19. A Comparison Between Articaine Mandibular Infiltration and Lidocaine Mandibular Block Anesthesia in Second Primary Molar:A Randomized Clinical Trial, Dental Research Journal (2022)
20. Effect of Intraosseous Injection Versus Inferior Alveolar Nerve Block As Primary Pulpal Anaesthesia of Mandibular Posterior Teeth With Symptomatic Irreversible Pulpitis: A Prospective Randomized Clinical Trial, Acta odontologica Scandinavica (2018)
21. The Efficacy Comparison of Ibuprofen, Acetaminophen-Codeine, and Placebo Premedication Therapy on the Depth of Anesthesia During Treatment of Inflamed Teeth, Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontology (2006)
22. Comparison of Success Rate and Onset Time of Two Different Anesthesia Techniques, Medicina Oral, Patologia Oral y Cirugia Bucal (2015)
23. Anaesthetic Efficacy of Lidocaine/Clonidine for Inferior Alveolar Nerve Block in Patients With Irreversible Pulpitis, International Endodontic Journal (2017)
24. The Effect of Orally Administered Ketamine on Requirement for Anesthetics and Postoperative Pain in Mandibular Molar Teeth With Irreversible Pulpitis., Journal of oral science (2011)
25. Injection of Lidocaine Alone Versus Lidocaine Plus Dexmedetomidine in Impacted Third Molar Extraction Surgery, a Double-Blind Randomized Control Trial for Postoperative Pain Evaluation, Pain Research and Management (2021)
26. Effect of Sodium Bicarbonate-Buffered Lidocaine on the Success of Inferior Alveolar Nerve Block for Teeth With Symptomatic Irreversible Pulpitis: A Prospective, Randomized Double-Blind Study, Journal of Endodontics (2015)
27. Anesthetic Efficacy of Gow-Gates Nerve Block, Inferior Alveolar Nerve Block, and Their Combination in Mandibular Molars With Symptomatic Irreversible Pulpitis: A Prospective, Randomized Clinical Trial, Journal of Endodontics (2018)
28. Anesthetic Success Rate of Inferior Alveolar Nerve Block for Mandibular Molars With Symptomatic Irreversible Pulpitis in Women Taking Antidepressants, Iranian Endodontic Journal (2022)
29. Comparative Effects of Premedication With Ibuprofen and Essential Oil of Urtica Dioica on Post-Endodontic Pain: Clinical Trial, Journal of Dentistry (Iran) (2024)
30. Postoperative Pain of Single-Visit Endodontic Treatment With Gutta-Percha Versus Mta Filling: A Randomized Superiority Trial, BMC Oral Health (2023)
31. Comparison of Benzydamine Hydrochloride Mouthwash 0.15% and Ibuprofen in Reducing Postoperative Pain During 24 Hours After Crown Lengthening: A Randomized Clinical Trial, Open Dentistry Journal (2020)
32. Effect of Massage on the Success of Anesthesia and Infiltration Injection Pain in Maxillary Central Incisors: Double-Blind, Crossover Trial, Dental Hypotheses (2017)
33. Effects of Acetaminophen and Ibuprofen on Pulpal Anaesthesia Immediately After Pulpectomy of Primary Maxillary Molars, Iranian Endodontic Journal (2019)
34. Effect of Three Different Injection Sites on the Success of Anterior Middle Superior Alveolar Nerve Block With 3% Mepivacaine: A Randomized Controlled Trial, Journal of Contemporary Dental Practice (2016)
35. Evaluation of Effects of Acupancture in Reduces Pain After, Journal of Isfahan Medical School (2011)
36. Anaesthetic Efficacy of Incorporating Different Additives Into Lidocaine for the Inferior Alveolar Nerve Block: A Systematic Review With Meta-Analysis and Trial Sequential Analysis, International Endodontic Journal (2022)
37. Effect of Fentanyl on the Success of Inferior Alveolar Nerve Block for Teeth With Symptomatic Irreversible Pulpitis: A Randomized Clinical Trial, Giornale Italiano di Endodonzia (2022)
38. Effects of Buffering and Preparation Time of Topical Anesthetics on Pain of Injection Into Oral Mucosa, Journal of Isfahan Medical School (2012)
39. Sealing Ability of Mta and Cem Cement As Root-End Fillings of Human Teeth in Dry, Saliva or Bloodcontaminated Conditions, Iranian Endodontic Journal (2010)
40. Supplementing Epidural Lidocaine With Midazolam: Effect on Sensorymotor Block Level, Acta Anaesthesiologica Taiwanica (2004)
41. Effect of Vibration Devices on Pain Associated With Dental Injections in Children: A Systematic Review and Meta-Analysis, Australian Dental Journal (2021)
42. Effects of Lidocaine on Reducing the Need for Anesthetic Drugs During Ophthalmologic Surgeries, Journal of Isfahan Medical School (2013)
43. Evaluation of the Apical Microleakage of Mta Fillapex, Ah26, and Endofill Sealers; [Avaliacao Da Microinfiltracao Apical De Cimentos Mta Fillapex Ah26 E Endofill], Brazilian Dental Science (2020)
44. The Comparison of Spinal Anesthesia With General Anesthesia on the Postoperative Pain Scores and Analgesic Requirements After Elective Lower Abdominal Surgery: A Randomized, Double-Blinded Study, Journal of Research in Medical Sciences (2013)
45. The Effect of Micro‑Osteoperforation on Root Resorption,Pulp Vitality, and Biological Changes of Teeth Subjected to Orthodontic Tooth Movement:A Systematic Review Study, Dental Research Journal (2023)
46. Influence of Intracanal Irrigants on Coronal Fracture Resistance of Endodontically Treated and Bleached Teeth: An in Vitro Study, Contemporary Clinical Dentistry (2017)
47. The Accuracy of Three Apex Locators in Determining the Location of Strip Root Perforation in Different Environments, Iranian Endodontic Journal (2021)
48. Topical Lidocaine Plus Diclofenac As a Local Anesthetic Agent in Central Venous Catheterization; a Randomized Controlled Clinical Trial, Archives of Academic Emergency Medicine (2021)
49. Technical Quality of Root Canal Therapies Performed by Novice Dental Students in Preclinical Practice, Dental Research Journal (2015)
50. Effects of Open and Closed Tracheal Suctioning on Pain in Mechanically Ventilated Patients, Iranian Journal of Nursing and Midwifery Research (2020)