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The Influence of Maternal Ketonuria on Fetal Well-Being Tests in Postterm Pregnancy Pubmed



Hamdi K1 ; Bastani P1 ; Gafarieh R1 ; Mozafari H2 ; Hashemi SH3 ; Ghotbi MH4, 5
Authors
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Authors Affiliations
  1. 1. Department of Obstetrics and Gynecology, Al-Zahra Hospital, Tabriz University of Medical Sciences, Tabriz, Iran
  2. 2. Department of Internal Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
  3. 3. Department of Pathology, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran
  4. 4. Department of Digestive Research Center, Tehran University of Medical Sciences, Tehran, Iran
  5. 5. Department of Digestive Research Center, Shariati Hospital, Tehran 14114, Kargar Shomali Ave., Iran

Source: Archives of Iranian Medicine Published:2006


Abstract

Background: Although it is well-known that postterm pregnancies are associated with the risk of perinatal morbidity and mortality, a comprehensive study on its management is lacking. The aim of present study was to determine whether ketonuria is associated with abnormal fetal test results in pregnancies >40 weeks of gestation. Methods: In this analytical cross sectional study, a total of 360 pregnant women with gestational age of >40 weeks were evaluated in two hospitals during 2003-2004. For each woman, urinary ketones, glucose, pH, proteins, and specific gravity were measured by total screen LSG tapes (Rapignost); in addition, biophysical profile test was recorded and the amniotic fluid index was assessed by ultrasonography. Results: Ketonuria was found in 34 women (9.44%). Statistical analyses showed that maternal ketonuria was associated with oligohydramnios, abnormal fetal tests, and a significant increase in fetal heart rate decelerations. Conclusion: Patients with clinically-detectable ketonuria have higher risk for abnormal fetal tests in comparison with those without the disease.
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