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Resveratrol-Loaded Nanocarriers: Characteristics, Sources, Health Effects, Recent Delivery Systems, and Their Food and Biomedical Applications Publisher



Rostami M1, 2 ; Beheshtizadeh N3, 4 ; Mazaheri EL4 ; Mirzaei G1 ; Andishmand H5 ; Mafi A6 ; Esfandiari Z7 ; Safavizadeh V8 ; Assadpour E9, 10 ; Sani MA1 ; Ahari H11 ; Jafari SM12, 13
Authors
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Authors Affiliations
  1. 1. Division of Food Safety and Hygiene, Department of Environmental Health Engineering, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Food Science and Nutrition Group (FSAN), Universal Scientific Education and Research Network (USERN), Tehran, Iran
  3. 3. Department of Tissue Engineering, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz, Iran
  4. 4. Regenerative Medicine Group (REMED), Universal Scientific Education and Research Network (USERN), Tehran, Iran
  5. 5. Department of Food Hygiene and Safety, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
  6. 6. Department of Clinical Biochemistry, School of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan, Iran
  7. 7. Nutrition and Food Security Research Center, Department of Food Science and Technology, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran
  8. 8. Department of Biophysics/Nanobiotechnology, Faculty of Bioscience, Tarbiat Modares University, Tehran, Iran
  9. 9. Food Industry Research Co., Gorgan, Iran
  10. 10. Food and Bio-Nanotech International Research Center (Fabiano), Gorgan University of Agricultural Sciences and Natural Resources, Gorgan, Iran
  11. 11. Department of Food Science and Technology, Science and Research Branch, Islamic Azad University, Tehran, Iran
  12. 12. Department of Food Materials and Process Design Engineering, Gorgan University of Agricultural Sciences and Natural Resources, Gorgan, Iran
  13. 13. Halal Research Center of IRI, Iran Food and Drug Administration, Ministry of Health and Medical Education, Tehran, Iran

Source: Food Bioscience Published:2024


Abstract

Resveratrol (3,5,4′-trihydroxystilbene, RES) is a polyphenolic phytoalexin widely studied in the recent years due to its known several biological activities. In spite of the potential benefits of RES, its use is restricted because of its photosensitivity, low solubility, and fast metabolism, which intensely challenge its bioactivity and bioavailability. As RES is unstable against environmental conditions and due to its low bioavailability, multiple methods have been provided for the encapsulation of RES to facilitate its practical application in various fields. Encapsulation is introduced as an appropriate strategy in order to maintain stability, high absorption, and sustained release rate of RES. This review attempts to discuss the recent techniques used in loading RES in micro/nano-carriers and explain their wide applications in food and biomedical industries. © 2024 Elsevier Ltd
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