Isfahan University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Refined Grains Consumption Is Associated With a Greater Odds of Glioma Publisher Pubmed



Mousavi SM1, 2 ; Rigi S1 ; Shayanfar M3 ; Mohammadshirazi M3 ; Sharifi G4 ; Esmaillzadeh A1, 5, 6
Authors
Show Affiliations
Authors Affiliations
  1. 1. Department of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Students’ Scientific Research Center (SSRC), Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Department of Clinical Nutrition and Dietetics, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  4. 4. Department of Neurosurgery, Loghman Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  5. 5. Obesity and Eating Habits Research Center, Endocrinology and Metabolism Molecular Cellular Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran
  6. 6. Food Security Research Center, Department of Community Nutrition, Isfahan University of Medical Sciences, Isfahan, Iran

Source: Nutritional Neuroscience Published:2022


Abstract

Objective: Grain consumption has been associated with brain carcinogenesis in earlier studies, however, no data are available examining the association between refined grains consumption and risk of glioma. The current study was done to investigate the association between refined grains consumption and risk of glioma in Iranian adults. Methods: This hospital-based case-control study was performed on 128 pathologically confirmed cases with glioma and 256 age- and sex-matched controls in Tehran, Iran. Dietary intakes of participants including refined grains consumption were collected using a validated Block-format 123-item detailed food frequency questionnaire (FFQ). Refined grains were considered as the sum of white breads, pasta, rice, boiled and fried potato, sweets, and cookies. Results: A significant positive association was found between refined grains consumption and glioma (OR: 3.51, 95% CI: 1.97–6.26, P trend<0.001). This association did not change after adjustment for energy intake (OR: 4.30, 95% CI: 2.27–8.15, P trend<0.001). After controlling for potential confounders, those in the top tertile of refined grains consumption were significantly more likely to have glioma than those in the bottom tertile (OR: 2.92, 95% CI: 1.38–6.17, P trend = 0.007). This significant association remained unchanged, even after further adjustment for other dietary variables (OR: 2.54, 95% CI: 1.15–5.63, P trend = 0.02) and BMI (OR: 2.49, 95% CI: 1.12–5.53, P trend = 0.03). Conclusion: We found a significant positive association between refined grains consumption and odds of glioma. Further prospective cohort studies are needed to confirm these findings. © 2020 Informa UK Limited, trading as Taylor & Francis Group.
Other Related Docs
10. A Case-Control Study on Dietary Calcium Intake and Risk of Glioma, European Journal of Cancer Prevention (2021)
14. A Case-Control Study on Dietary Quality Indices and Glioma, British Journal of Nutrition (2019)
26. The Association of Dietary Inflammatory Index and Cognitive Function in Iranian Elders, Recent Advances in Food, Nutrition and Agriculture (2024)
34. A Case-Control Study on Egg Consumption and Risk of Stroke Among Iranian Population, Journal of health, population, and nutrition (2017)
35. The Association Between Carbohydrate Intake and Metabolic Syndrome, Journal of Isfahan Medical School (2011)
39. Dairy Consumption and Risk of Stroke: A Case‑Control Study, International Journal of Preventive Medicine (2016)
47. Protein Consumptions in Stroke Patients, Journal of Research in Medical Sciences (2013)