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Association Between Serum Ferritin and Goitre in Iranian School Children Publisher Pubmed



Hashemipour M1 ; Soheilipour F1 ; Keshteli AH1, 2, 3 ; Siavash M1 ; Amini M1 ; Kelishadi R4
Authors
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Authors Affiliations
  1. 1. Isfahan Endocrine and Metabolism Research Center, Isfahan, Iran
  2. 2. Medical Students Research Center, School of Medicine, Isfahan, Iran
  3. 3. Vice Chancellery for Research, Isfahan, Iran
  4. 4. Preventive Pediatric Cardiology Department, Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan, Iran

Source: Journal of Health, Population and Nutrition Published:2010


Abstract

Despite long-standing supplementation of iodine in Iran, the prevalence of goitre among general people remains high in some regions. The study investigated the role of iron status in the aetiology of goitre in school children in Isfahan, Iran. Two thousand three hundred and thirty-one school children were selected by multi-stage random sampling. Thyroid size was estimated by inspection and palpation. Urinary iodine concentration (UIC) and serum ferritin (SF) were measured. Overall, 32.9% of the children had goitre. The median UIC was 195.5 μg/L. The mean±SD of SF in the goitrous and non-goitrous children was 47.65±42.51 and 44.55±37.07 μg/L respectively (p=0.52). The prevalence of iron deficiency in goitrous and non-goitrous children was 9.6% and 3.1% respectively (p=0.007). Goitre is still prevalent in school children of Isfahan. However, their median UIC was well in the accepted range. Iron deficiency is associated with goitre in a small group of goitrous children. The role of goitrogens should also be investigated in this region. © International Centre for Diarrhoeal Disease Research, Bangladesh.
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