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Squamous Cell Carcinoma Arising in a Chronic, Nonhealing Diabetic Foot Ulcer Pubmed



Larijani B1 ; Tavangar SM2 ; Bandarian F3
Authors
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Authors Affiliations
  1. 1. Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Department of Pathology, Shariati Hospital, Tehran University of Medical Sciences, Iran
  3. 3. Diabetes Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Diabetes Clinic, Cross Heyat, Shahrivar Ave, North Kargar St, Tehran, 14417, Iran

Source: Wounds Published:2017


Abstract

Diabetic foot ulcers (DFUs) are a severe and costly complication of diabetes and may result in foot amputation. Case Report. A 69-year-old man with a 10-year history of type 2 diabetes, who was undergoing routine care for diabetes in the authors' clinic, presented with a nonhealing DFU of his right foot that persisted for 4 years. The wound did not respond to conventional treatments, and imaging studies were normal. His 2 biopsies tested negative for malignancy. The DFU was fully removed surgically. Following surgical removal, squamous cell carcinoma (SCC) was diagnosed in the histologic study of the wound. Conclusion. Clinicians should consider a diagnosis of SCC in any chronic, nonhealing DFU. Early surgical resection of a chronic, nonhealing DFU may prevent development of SCC in an ulcer. © 2017 HMP Communications. All rights reserved.
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