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The Quality of Life in Epidermolysis Bullosa (Eb-Qol) Questionnaire: Translation, Cultural Adaptation, and Validation Into the Farsi Language Publisher



Yazdanshenas A1 ; Naderi E1 ; Moravvej H2 ; Heidari K3 ; Faghankhani M4 ; Vahidnezhad H4 ; Mozafari N2, 5
Authors
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Authors Affiliations
  1. 1. Department of Educational Science, Science and Research Branch, Islamic Azad University, Tehran, Iran
  2. 2. Skin Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  3. 3. Department of Epidemiology and Biostatistics, Faculty of Health, Tehran University of Medical Sciences, Tehran, Iran
  4. 4. Department of Dermatology and Cutaneous Biology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, United States
  5. 5. Department of Dermatology, Loghman Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran

Source: International Journal of Women's Dermatology Published:2020


Abstract

Background: Defining the quality of life in the patients with epidermolysis bullosa (EB) is important in patient care and management. Evaluation of quality of life requires a valid and reliable scale. The Quality of Life in Epidermolysis Bullosa (EB-QoL) questionnaire, which is an English 17-item questionnaire, has emerged as a useful tool for assessing the quality of life in the patients with EB. Objective: This study aimed to evaluate the psychometric properties of the Farsi version of the EB-QoL questionnaire among a group of Iranian patients with EB. Methods: The Farsi version of the EB-QoL questionnaire was finalized after translation and back-translation. From the 100 patients with EB invited to participate in the study, 83 completed the questionnaire (response rate: 83%). Subsequently, the content validity and construct validity of the questionnaire were assessed. The reliability of the questionnaire was assessed with Cronbach's alpha. Moreover, the correlation between EB-QoL scores and EB severity scores (based on the Birmingham Epidermolysis bullosa severity score scale) was evaluated. Results: A total of 83 patients (40 male and 43 female) with a median age of 15 years (interquartile range, 9–24 years) and an age range between 3 and 43 years were enrolled in this study. Mean ± standard deviation scores from the EB-QoL questionnaire were 43.7 ± 9.9. The translated EB-QoL questionnaire showed a high internal consistency (Cronbach alpha = 0.90) and adequate item-total correlation. Also, there was a significant correlation between EB-QoL and EB severity scores (r = 0.39; p < .001). Conclusion: The Farsi version of EB-QoL questionnaire has acceptable validity and reliability. Thus, the questionnaire can be used for future studies to assess the quality of life among Iranian patients with EB. © 2020 The Author(s)
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