Measurement of Neutron Equivalent Dose in the Thyroid, Chiasma, and Lens for Patients Undergoing Pelvic Radiotherapy: A Phantom Study Publisher Pubmed



Shojaei M¹ ; Rashedi S¹ ; Chakoli AN² ; Karimi AH¹ ; Geraily G^{1, 3, 4} Show Affiliations
Source: Applied Radiation and Isotopes Published:2022

Abstract

Radiotherapy is one of the most common methods for treating malignant diseases, whose ultimate goal is to deliver lethal doses to tumor cells. One of the unwanted consequences of radiotherapy is secondary radiation outside the treatment field, which imposes additional doses to healthy tissues and organs, specifically neutron doses, which we aim to evaluate. Therefore, this study aims to measure the fast neutron equivalent dose and the risk of secondary cancer in the thyroid, chiasm, and lenses in the treatment of the pelvic area. In this study, CR-39 detectors were used to measure the equivalent fast neutron dose in different sections of the RANDO Phantom (thyroid, chiasm, and lenses) and were irradiated by the energy of 18 MV on Varian Clinac 2100 C-D linear accelerator. CR-39 detectors were calibrated with predetermined doses by an Am–Be neutron source. Then, after etching and reading processes, the equivalent dose of fast neutrons was determined. According to the results, the fast neutron doses in the thyroid, right and left eye lenses, and chiasm were 0.613 ± 0.024, 0.835 ± 0.040, 0.866 ± 0.016, and 0.685 ± 0.045 mSv/Gy, respectively. Moreover, the secondary cancer risks in the unshielded organs are 0.004, 0.029, 0.030, and 0.025 for the thyroid, right and left eye lenses, and chiasm, respectively. In conclusion, the contribution of neutrons to the secondary doses in the out-of-field organs is significant and should not be ignored. © 2022 Elsevier Ltd