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Fenugreek (Trigonella Foenum-Graecum L.) in Women's Health: A Review of Clinical Evidence and Traditional Use Publisher



Akhtari E1, 2 ; Ram M3, 4 ; Zaidi SMA5 ; Marques AM6 ; Rahimi R7, 8 ; Bahramsoltani R4, 7
Authors
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Authors Affiliations
  1. 1. Research Institute for Complementary Medicine, Iran University of Medical Sciences, Tehran, Iran
  2. 2. School of Persian Medicine, Iran University of Medical Sciences, Tehran, Iran
  3. 3. Drug Design and Bioinformatics Unit, Medical Biotechnology Department, Biotechnology Research Center, Pasteur Institute of Iran, Tehran, Iran
  4. 4. PhytoPharmacology Interest Group (PPIG), Universal Scientific Education and Research Network (USERN), Tehran, Iran
  5. 5. Department of Moalajat (Internal Medicine), Hakim Syed Ziaul Hasan Government Unani Medical Collegeo, Bhopal, India
  6. 6. Department of Natural Products, Oswaldo Cruz Foundation (FIOCRUZ), Laboratory of Technology for Biodiversity in Health (Tecbio) Farmanguinhos, Rio de Janeiro, Brazil
  7. 7. Department of Traditional Pharmacy, School of Persian Medicine, Tehran University of Medical Sciences, Tehran, Iran
  8. 8. Evidence-Based Medicine Group, Pharmaceutical Sciences Research Center, Tehran University of Medical Sciences, Tehran, Iran

Source: Journal of Herbal Medicine Published:2024


Abstract

Introduction: Fenugreek (Trigonella foenum-graecum L.) is a medicinal plant widely used in culinary and medicine all over the world. The seeds are a valuable traditional remedy in gynaecological problems. This paper aims to review clinical evidence and traditional use of fenugreek in women's health, along with possible pharmacological mechanisms. Methods: Electronic databases including PubMed, Scopus, and Web of Science, as well as ethnopharmacological studies and textbooks of traditional medicines were searched to collect all relevant data. Results: Fenugreek is used for gynaecological problems in different traditional medicines, including Persian medicine and Ayurveda. It has also been widely used in ethnomedicine of different parts of the world for women's health. Several clinical studies confirm the beneficial effects of fenugreek in breastfeeding, dysmenorrhoea, polycystic ovary syndrome, and menopause. There are limited studies on the use of this plant in ovarian diseases, infertility, and vaginal atrophy. Conclusions: Conclusively, fenugreek is a valuable medicinal plant in women's health, and thus future studies are recommended to further clarify the efficacy and underlying mechanisms of this plant in this category of diseases. © 2023 Elsevier GmbH