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Systematic Review and Meta-Analysis of Human Papillomavirus Prevalence and Types Among Women With Normal Cervical Cytology in the Eastern Mediterranean Region Publisher



Farahmand M1 ; Shoja Z2 ; Arashkia A2 ; Salavatiha Z1 ; Jalilvand S1
Authors
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Authors Affiliations
  1. 1. Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Department of Molecular Virology, Pasteur Institute of Iran, Tehran, Iran

Source: Future Virology Published:2019


Abstract

Aim: To predict the impact of human papillomavirus (HPV) vaccines in the Eastern Mediterranean Region (EMRO), knowing the prevalence and type distribution of HPV are mandatory. Methods: This study investigated 26,536 women with normal cervical cytology based on the data available from 13 countries of EMRO. Results: The HPV prevalence estimated to be 9.3% (CI = 7.1-12.0). The five most frequent HPV types were HPV 16 (2.3%), 18 (0.7%), 6 (0.7%), 11 (0.6%) and 31 (0.5%). The prevalence of multiple infections of HPV was observed in 1.6% of all cases. Conclusion: The present meta-analysis provides a comprehensive summary of HPV type distribution in normal cervical cytology in EMRO region to estimate and predict the impact of HPV vaccines. © 2019 Future Medicine Ltd.
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