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Risk Factors for Atherosclerotic Cardiovascular Disease (Ascvd) in Healthcare Professionals of Azar Cohort Study: A Cross-Sectional Study Publisher



Roshanravan N1, 2 ; Tutunchi H3 ; Parvizi R2 ; Bastani S4 ; Jafarabadi MA5, 6, 7, 8 ; Faramarzi E9 ; Alamdari NM3 ; Ghoreishi Z10 ; Tarighat F11 ; Mehravani K2 ; Vahedinezhad M12 ; Namazi N13 ; Ghaffari S2
Authors
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Authors Affiliations
  1. 1. Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
  2. 2. Cardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
  3. 3. Endocrine Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
  4. 4. Stem Cell and Regenerative Medicine Institute, Tabriz University of Medical Sciences, Tabriz, Iran
  5. 5. Cabrini Research, Cabrini Health, Malvern, 3144, VIC, Australia
  6. 6. School of Public Health and Preventive Medicine, Monash University, Melbourne, 3004, VIC, Australia
  7. 7. Department of Psychiatry, School of Clinical Sciences, Monash University, Clayton, 3168, VIC, Australia
  8. 8. Road Traffic Injury Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
  9. 9. Liver and Gastrointestinal Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
  10. 10. Nutrition Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
  11. 11. Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran
  12. 12. Rajaie Cardiovascular Medical and Research Center, School of Medicine, Iran University of Medical Sciences, Tehran, Iran
  13. 13. Diabetes Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran

Source: Health Promotion Perspectives Published:2024


Abstract

Background: Atherosclerotic cardiovascular disease (ASCVD) is considered a worldwide health problem associated with high morbidity, mortality, and cost of care. In the present study, we examined risk-enhancing factors for ASCVD in healthcare workers of the AZAR cohort population. Methods: Data from a total of 500 participants were used for this cross-sectional study. Demographic characteristics, anthropometric indices, biochemical factors, and blood pressure were assessed. To evaluate the associations of ASCVD with the parameters mentioned above, univariate and multivariate logistic regression analyses were conducted. Results: The total frequency of subjects with severe (≥7.5) and low (<7.5) ASCVD was 7.6% (95% CI: 5.4-10.3), and 90.6% (95% CI: 87.7-93.0), respectively. The top strongest links were found between ASCVD and atherogenic index of plasma (AIP) (odds ratio [OR]: 12.8, 95% CI: 3.2-49.9), diabetes (OR: 7.6, 95% CI: 2.8-25), and daily smoking (OR: 7.0, 95% CI: 2.8-20). Based on a multivariate logistic regression model, low-density lipoprotein cholesterol (LDL-C)/apolipoprotein B (Apo b), diabetes, hematocrit, age, Triglycerides (TG)/high-density lipoprotein cholesterol (HDL-C), systolic blood pressure, HDL-C, apolipoprotein A-I (Apo A-I), hemoglobin, and Apo B/Apo A-I have significant associations with ASCVD severity. Conclusion: In conclusion, the present study showed significant associations between the severity of ASCVD with some parameters among healthcare workers of AZAR cohort study. © 2024 The Author(s).