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Sulfur-Containing Compounds From the Roots of Ferula Latisecta and Their Cytotoxic Activities Publisher Pubmed



Soltani S1 ; Amin GR1 ; Salehisourmaghi MH1 ; Schneider B2 ; Lorenz S2 ; Iranshahi M3
Authors
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Authors Affiliations
  1. 1. Department of Pharmacognosy, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Max-Planck-Institute for Chemical Ecology, Beutenberg Campus, Jena, Germany
  3. 3. Biotechnology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran

Source: Fitoterapia Published:2018


Abstract

Five new sulfur-containing compounds, with a new geometry (cis) of the propenyl moiety, and five known compounds were isolated from the roots of Ferula latisecta. The structures of these compounds, were elucidated on the basis of spectroscopic data including 1D and 2D NMR experiments and HRMS. All of the isolated compounds were tested against A2780, A549, HeLa, and HCT116 human cancer cell lines and some of them showed moderate cytotoxic activities. © 2017