Tehran University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Aspergillus Coinfection Among Patients With Pulmonary Tuberculosis in Asia and Africa Countries; a Systematic Review and Meta-Analysis of Cross-Sectional Studies Publisher Pubmed



Hosseini M1 ; Shakerimoghaddam A2 ; Ghazalibina M4 ; Khaledi A2
Authors
Show Affiliations
Authors Affiliations
  1. 1. Department of Biomedical Engineering, Amirkabir University of Technology, Tehran, Iran
  2. 2. Infectious Diseases Research Center, Department of Microbiology and Immunology, Faculty of Medicine, Kashan University of Medical Sciences, Kashan, Iran
  3. 3. Department of Microbiology and Immunology, Faculty of Medicine, Kashan University of Medical Sciences, Kashan, Iran
  4. 4. Department of Microbiology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran

Source: Microbial Pathogenesis Published:2020


Abstract

Progress of the disease and prolonged treatment with antibiotics or immunosuppressive agents makes tuberculosis patients susceptible to fungal infections. This study aimed to determine the prevalence of pulmonary Aspergillus coinfection among patients with pulmonary tuberculosis in Asia and Africa. The present review of cross-sectional studies was conducted on the prevalence of pulmonary Aspergillus coinfection among patients with pulmonary tuberculosis according to the PRISMA Protocol. Literatures published online in English from January 2001 to March 2019 via key databases such as Web of Science, MEDLINE, PubMed, Scopus, and Cochrane Library were searched. The used MeSH and non-MeSH keywords were; “pulmonary fungal”, “pulmonary coinfection”, OR “Pulmonary mycosis”, “pulmonary fungal infections/agents”, OR “Polymicrobial infection”, OR “Secondary infection”, OR “Mixed infections”, “pulmonary aspergillosis”, “fungi coinfection”, “Fungal co-colonization”, AND “pulmonary tuberculosis”, OR “pulmonary TB”, AND “Asia” AND “Africa”. Finally, data analyzed using Comprehensive Meta-Analysis software (CMA). The combined Aspergillus coinfection among patients with pulmonary tuberculosis was 15.4% (95% CI: 11.4–20.5), Q = 105.8 and Z = 9.57 in Asia and Africa. The most frequency of Aspergillus spp. was related to A. fumigatus with a combined prevalence of 57.6%. Most of the studies included in the present review showed a higher Aspergillus coinfection in the age group of 40 years and higher. Also, the existence of a correlation between increasing age and Aspergillus coinfection was reported (p < 0.05). The present review showed a high combined Aspergillus coinfection among patients with pulmonary tuberculosis in Asia and Africa. Also, amongst the Aspergillus spp., the most frequent was related to A. fumigatus. © 2020 Elsevier Ltd
Related Docs
View other Related Docs
1. Pulmonary Fungal Co-Infection Prevalence Among Iranian Patients With Pulmonary Tuberculosis: A Systematic Review and Meta-Analysis, Sains Malaysiana (2019)
2. The Effects of Silymarin Consumption on Inflammation and Oxidative Stress in Adults: A Systematic Review and Meta-Analysis, Inflammopharmacology (2024)
3. The Effect of Grape Products on Liver Enzymes: A Systematic Review and Meta-Analysis of Randomized Controlled Trials, Phytotherapy Research (2022)
4. The Effects of Lycopene and Tomato Consumption on Cardiovascular Risk Factors in Adults: A Grade Assessment Systematic Review and Meta-Analysis, Current Pharmaceutical Design (2023)
5. Global Prevalence of Neisseria Gonorrhoeae Infection in Pregnant Women: A Systematic Review and Meta-Analysis, Clinical Microbiology and Infection (2023)
6. Global Incidence of Surgical Site Infections Following Caesarean Section: A Systematic Review and Meta-Analysis, Journal of Hospital Infection (2023)
7. The Cardiometabolic Benefits of Okra-Based Treatment in Prediabetes and Diabetes: A Systematic Review and Meta-Analysis of Randomized Controlled Trials, Frontiers in Nutrition (2024)
8. Comparison of Cartilage With Temporalis Fascia Tympanoplasty: A Meta-Analysis of Comparative Studies, Laryngoscope (2017)
Experts (# of related papers)
View all Related Experts
Mahroo Rezaeinejad (3)
Ata Garajei (2)
Other Related Docs
9. Tb and Interstitial Lung Disease: A Systematic Review and Meta-Analysis, International Journal of Tuberculosis and Lung Disease (2024)
10. Is Leukocyte Telomere Length Related With Lung Cancer Risk?: A Meta-Analysis, Iranian Biomedical Journal (2017)
11. Short-Term Ambient Temperature Variations and Incidence of Preterm Birth: A Systematic Review and Meta-Analysis, International Journal of Hygiene and Environmental Health (2024)
12. Heterologous Versus Homologous Covid-19 Booster Vaccinations for Adults: Systematic Review With Meta-Analysis and Trial Sequential Analysis of Randomised Clinical Trials, BMC Medicine (2024)
13. The Effects of Conjugated Linoleic Acid Supplementation on Cardiovascular Risk Factors in Patients at Risk of Cardiovascular Disease: A Grade-Assessed Systematic Review and Dose-Response Meta-Analysis, British Journal of Nutrition (2024)
14. Hepatitis C Infection Seroprevalence in Pregnant Women Worldwide: A Systematic Review and Meta-Analysis, eClinicalMedicine (2023)
15. The Effects of Gymnema Sylvestre Supplementation on Lipid Profile, Glycemic Control, Blood Pressure, and Anthropometric Indices in Adults: A Systematic Review and Meta-Analysis, Phytotherapy Research (2023)
16. A Meta-Analysis to Evaluate the Prevalence of Maxillofacial Trauma Caused by Various Etiologies Among Children and Adolescents, Dental Traumatology (2023)
17. Meta-Analysis of Promoter Methylation in Eight Tumor-Suppressor Genes and Its Association With the Risk of Thyroid Cancer, PLoS ONE (2017)
18. The Long-Term Effect of Exposure to Respirable Particulate Matter on the Incidence of Myocardial Infarction: A Systematic Review and Meta-Analysis Study, Environmental Science and Pollution Research (2022)
19. Safety and Efficacy of Two Different Doses of Everolimus in Kidney Transplantation: A Systematic Review and Meta-Analysis, Iranian Journal of Kidney Diseases (2017)
20. Association of Serum Omentin Levels With Microvascular Complications of Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis, Journal of Diabetes and Metabolic Disorders (2023)
21. Impact of Melatonin Supplementation on Glycemic Parameters in Patients With Type 2 Diabetes: A Systematic Review and Meta-Analysis, Current Pharmaceutical Design (2025)
22. Association Between the Cyp1a1 Mspi Polymorphism and Risk of Head and Neck Cancer: A Meta-Analysis, Scientific Reports (2022)
23. The Effect of Combination Therapy With Statins and Ezetimibe on Proinflammatory Cytokines: A Systematic Review and Meta-Analysis of Randomized Controlled Trials, International Immunopharmacology (2022)
24. The Effects of Conjugated Linoleic Acid Supplementation on Glycemic Control, Adipokines, Cytokines, Malondialdehyde and Liver Function Enzymes in Patients at Risk of Cardiovascular Disease: A Grade-Assessed Systematic Review and Dose–Response Meta-Analysis, Nutrition Journal (2023)
25. Association of Helicobacter Pylori Infection With the Risk of Metabolic Syndrome and Insulin Resistance: An Updated Systematic Review and Meta-Analysis, Diabetology and Metabolic Syndrome (2021)
26. The Association Between Overall, Healthy, and Unhealthy Plant-Based Diet Indexes and Risk of All-Cause and Cause-Specific Mortality: A Systematic Review and Dose-Response Meta-Analysis of Prospective Cohort Studies, Food and Function (2025)
27. Evaluation of Apr1 Gene Expression in Candida Albicans Strains Isolated From Patients With Multiple Sclerosis, Jundishapur Journal of Microbiology (2016)
28. Association Analyses Identify 38 Susceptibility Loci for Inflammatory Bowel Disease and Highlight Shared Genetic Risk Across Populations, Nature Genetics (2015)
29. The Association Between Dietary Inflammatory Potential and Risk of Total and Site-Specific Colorectal Cancer: A Systematic Review and Meta-Analysis of Observational Studies, British Journal of Nutrition (2025)
30. The Effects of Ursodeoxycholic Acid on Cardiometabolic Risk Factors: A Systematic Review and Meta-Analysis of Randomized Controlled Trials, BMC Cardiovascular Disorders (2025)
31. Occupational Arsenic Exposure and Digestive and Head and Neck Cancers: A Systematic Review and Meta-Analysis, Environmental Research (2024)
32. The Effects of Green Tea Extract Supplementation on Body Composition, Obesity-Related Hormones and Oxidative Stress Markers: A Grade-Assessed Systematic Review and Dose-Response Meta-Analysis of Randomised Controlled Trials, British Journal of Nutrition (2024)
33. The Challenge of Tuberculosis Diagnosis and Management in the Era of the Covid-19 Pandemic and Diabetes Mellitus, Archives of Clinical Infectious Diseases (2021)
34. Quality of Life in Elderly Iranian Population Using Leiden-Padua Questionnaire: A Systematic Review and Meta-Analysis, International Journal of Preventive Medicine (2017)
35. Effect of Carbohydrate Restriction on Body Weight in Overweight and Obese Adults: A Systematic Review and Dose–Response Meta-Analysis of 110 Randomized Controlled Trials, Frontiers in Nutrition (2023)
36. The Effects of Pomegranate Consumption on Obesity Indices in Adults: A Systematic Review and Meta-Analysis, Food Science and Nutrition (2024)
37. Prognostic Significance of Matrix Metalloproteinase-7 in Gastric Cancer Survival: A Meta-Analysis, PLoS ONE (2015)
38. Antioxidant Supplements and Breast Cancer: A Systematic Review and Meta-Analysis, International Journal of Cancer Management (2018)
39. Association Between Il-8 (-251T/A) and Il-6 (-174G/C) Polymorphisms and Oral Cancer Susceptibility: A Systematic Review and Meta-Analysis, Medicina (Lithuania) (2021)
40. The Global and Regional Survival Rate of Women With Breast Cancer: A Systematic Review and Meta-Analysis, Clinical Breast Cancer (2019)
41. The Association Between Parental Consanguinity and Primary Immunodeficiency Diseases: A Systematic Review and Meta-Analysis, Pediatric Allergy and Immunology (2017)
42. The Effects of Vitamin D and Omega-3 Co-Supplementation on Lipid Profile in Adults: A Systematic Review and Meta-Analysis, Nutrition and Food Science (2024)
43. The Effects of Raspberry Consumption on Lipid Profile and Blood Pressure in Adults: A Systematic Review and Meta-Analysis, Food Science and Nutrition (2024)
44. Glymphatic Pathway Dysfunction in Severe Obstructive Sleep Apnea: A Meta-Analysis, Sleep Medicine (2025)
45. Herbal Medicines for Type 1 Diabetes Mellitus, Cochrane Database of Systematic Reviews (2015)