International Clinimetric Evaluation of the Mg-Qol15, Resulting in Slight Revision and Subsequent Validation of the Mg-Qol15r

International Clinimetric Evaluation of the Mg-Qol15, Resulting in Slight Revision and Subsequent Validation of the Mg-Qol15r Publisher Pubmed

Burns TM¹ ; Sadjadi R² ; Utsugisawa K³ ; Gwathmey KG¹ ; Joshi A¹ ; Jones S¹ ; Bril V⁴ ; Barnett C⁴ ; Guptill JT⁵ ; Sanders DB⁵ ; Hobsonwebb L⁵ ; Juel VC⁵ ; Massey J⁵ ; Gable KL⁵ Show All Authors

Burns TM¹
Sadjadi R²
Utsugisawa K³
Gwathmey KG¹
Joshi A¹
Jones S¹
Bril V⁴
Barnett C⁴
Guptill JT⁵
Sanders DB⁵
Hobsonwebb L⁵
Juel VC⁵
Massey J⁵
Gable KL⁵
Silvestri NJ⁶
Wolfe G⁶
Cutter G⁷
Nagane Y³
Murai H⁸
Masuda M⁹
Farrugia ME¹⁰
Carmichael C¹⁰
Birnbaum S¹¹
Hogrel JY¹¹
Nafissi S¹²
Fatehi F¹²
Ou C¹³
Liu W¹³
Conaway M¹

Show Affiliations

1. University of Virginia, Department of Neurology, Charlottesville, 22908, VA, United States
2. University of Rochester, Rochester, NY, United States
3. Hanamaki General Hospital, Hanamaki, Japan
4. Toronto General Hospital, Toronto, Canada
5. Duke University, Durham, NC, United States
6. University at Buffalo, SUNY, Buffalo, NY, United States
7. University of Alabama, Birmingham, Birmingham, AL, United States
8. Neurological Institute, Kyushu University, Fukuoka, Japan
9. Tokyo Medical University, Tokyo, Japan
10. Institute of Neurological Sciences, Southern General Hospital, Glasgow, United Kingdom
11. Institut de Myologie, GH Pitie-Salpetriere, Paris, France
12. Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran
13. The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong Province, China

Source: Muscle and Nerve Published:2016

Abstract

Introduction: The MG-QOL15 is a validated, health-related quality of life (HRQOL) measure for myasthenia gravis (MG). Widespread use of the scale gave us the opportunity to further analyze its clinimetric properties. Methods: We first performed Rasch analysis on >1,300 15-item Myasthenia Gravis Quality of Life scale (MG-QOL15) completed surveys. Results were discussed during a conference call with specialists and biostatisticians. We decided to revise 3 items and prospectively evaluate the revised scale (MG-QOL15r) using either 3, 4, or 5 responses. Rasch analysis was then performed on >1,300 MG-QOL15r scales. Results: The MGQOL15r performed slightly better than the MG-QOL15. The 3-response option MG-QOL15r demonstrated better clinimetric properties than the 4- or 5-option scales. Relative distributions of item and person location estimates showed good coverage of disease severity. Conclusions: The MG-QOL15r is now the preferred HRQOL instrument for MG because of improved clinimetrics and ease of use. This revision does not negate previous studies or interpretations of results using the MG-QOL15. Muscle Nerve 54: 1015–1022, 2016. © 2016 Wiley Periodicals, Inc.

Experts (# of related papers)

Farzad Fatehi (1)

Shahriar Nafissi (1)

Style	Citing Format
MLA	Burns TM, et al.. "International Clinimetric Evaluation of the Mg-Qol15, Resulting in Slight Revision and Subsequent Validation of the Mg-Qol15r." Muscle and Nerve, vol. 54, no. 6, 2016, pp. 1015-1022.
APA	Burns TM, Sadjadi R, Utsugisawa K, Gwathmey KG, Joshi A, Jones S, Bril V, Barnett C, Guptill JT, Sanders DB, Hobsonwebb L, Juel VC, Massey J, Gable KL, Silvestri NJ, Wolfe G, Cutter G, Nagane Y, Murai H, ... Conaway M (2016). International Clinimetric Evaluation of the Mg-Qol15, Resulting in Slight Revision and Subsequent Validation of the Mg-Qol15r. Muscle and Nerve, 54(6), 1015-1022.
Chicago	Burns TM, Sadjadi R, Utsugisawa K, Gwathmey KG, Joshi A, Jones S, Bril V, et al.. "International Clinimetric Evaluation of the Mg-Qol15, Resulting in Slight Revision and Subsequent Validation of the Mg-Qol15r." Muscle and Nerve 54, no. 6 (2016): 1015-1022.
Harvard	Burns TM et al. (2016) 'International Clinimetric Evaluation of the Mg-Qol15, Resulting in Slight Revision and Subsequent Validation of the Mg-Qol15r', Muscle and Nerve, 54(6), pp. 1015-1022.
Vancouver	Burns TM, Sadjadi R, Utsugisawa K, Gwathmey KG, Joshi A, Jones S, et al.. International Clinimetric Evaluation of the Mg-Qol15, Resulting in Slight Revision and Subsequent Validation of the Mg-Qol15r. Muscle and Nerve. 2016;54(6):1015-1022.
BibTex	@article{ author = {Burns TM and Sadjadi R and Utsugisawa K and Gwathmey KG and Joshi A and Jones S and Bril V and Barnett C and Guptill JT and Sanders DB and Hobsonwebb L and Juel VC and Massey J and Gable KL and Silvestri NJ and Wolfe G and Cutter G and Nagane Y and Murai H and Masuda M and Farrugia ME and Carmichael C and Birnbaum S and Hogrel JY and Nafissi S and Fatehi F and Ou C and Liu W and Conaway M}, title = {International Clinimetric Evaluation of the Mg-Qol15, Resulting in Slight Revision and Subsequent Validation of the Mg-Qol15r}, journal = {Muscle and Nerve}, volume = {54}, number = {6}, pages = {1015-1022}, year = {2016} }
RIS	TY - JOUR AU - Burns TM AU - Sadjadi R AU - Utsugisawa K AU - Gwathmey KG AU - Joshi A AU - Jones S AU - Bril V AU - Barnett C AU - Guptill JT AU - Sanders DB AU - Hobsonwebb L AU - Juel VC AU - Massey J AU - Gable KL AU - Silvestri NJ AU - Wolfe G AU - Cutter G AU - Nagane Y AU - Murai H AU - Masuda M AU - Farrugia ME AU - Carmichael C AU - Birnbaum S AU - Hogrel JY AU - Nafissi S AU - Fatehi F AU - Ou C AU - Liu W AU - Conaway M TI - International Clinimetric Evaluation of the Mg-Qol15, Resulting in Slight Revision and Subsequent Validation of the Mg-Qol15r JO - Muscle and Nerve VL - 54 IS - 6 SP - 1015 EP - 1022 PY - 2016 ER -

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