Fabrication and Characterization of Electrospun Plla/Collagen Nanofibrous Scaffold Coated With Chitosan to Sustain Release of Aloe Vera Gel for Skin Tissue Engineering

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Fabrication and Characterization of Electrospun Plla/Collagen Nanofibrous Scaffold Coated With Chitosan to Sustain Release of Aloe Vera Gel for Skin Tissue Engineering Publisher

Salehi M¹ ; Farzamfar S² ; Bastami F³ ; Tajerian R⁴

Source: Biomedical Engineering - Applications# Basis and Communications Published:2016

Abstract

Background and aim: Healing of fire-induced wounds has been still a challenge in clinical issues. The aim of this study was to fabricate a nanofibrous poly (L-lactic acid)/collagen (PLLA/COL) scaffold with sustained release of aloe vera (AV) gel using a chitosan (CT)-coated layer for skin tissue engineering applications. Material and methods: Morphology, porosity, tensile strength, hydrophilicity, degradation rate, water vapor permeability and water uptake ratio of the scaffold were characterized. The behaviors of mouse fibroblasts (L929) were evaluated on the scaffold. Results: We observed that although the porosity of the scaffold was decreased, other characteristics were enhanced by coating a CT layer. The scaffold supports attachment, viability and proliferation of mouse fibroblasts. Conclusion: Consequently, the PLLA/COL scaffold coated with CT for sustained release of AV gel can be considered as a desirable scaffold for skin tissue engineering. © 2016 National Taiwan University.

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Style	Citing Format
MLA	Salehi M, et al.. "Fabrication and Characterization of Electrospun Plla/Collagen Nanofibrous Scaffold Coated With Chitosan to Sustain Release of Aloe Vera Gel for Skin Tissue Engineering." Biomedical Engineering - Applications# Basis and Communications, vol. 28, no. 5, 2016, pp. -.
APA	Salehi M, Farzamfar S, Bastami F, Tajerian R (2016). Fabrication and Characterization of Electrospun Plla/Collagen Nanofibrous Scaffold Coated With Chitosan to Sustain Release of Aloe Vera Gel for Skin Tissue Engineering. Biomedical Engineering - Applications# Basis and Communications, 28(5), -.
Chicago	Salehi M, Farzamfar S, Bastami F, Tajerian R. "Fabrication and Characterization of Electrospun Plla/Collagen Nanofibrous Scaffold Coated With Chitosan to Sustain Release of Aloe Vera Gel for Skin Tissue Engineering." Biomedical Engineering - Applications# Basis and Communications 28, no. 5 (2016): -.
Harvard	Salehi M et al. (2016) 'Fabrication and Characterization of Electrospun Plla/Collagen Nanofibrous Scaffold Coated With Chitosan to Sustain Release of Aloe Vera Gel for Skin Tissue Engineering', Biomedical Engineering - Applications# Basis and Communications, 28(5), pp. -.
Vancouver	Salehi M, Farzamfar S, Bastami F, Tajerian R. Fabrication and Characterization of Electrospun Plla/Collagen Nanofibrous Scaffold Coated With Chitosan to Sustain Release of Aloe Vera Gel for Skin Tissue Engineering. Biomedical Engineering - Applications# Basis and Communications. 2016;28(5):-.
BibTex	@article{ author = {Salehi M and Farzamfar S and Bastami F and Tajerian R}, title = {Fabrication and Characterization of Electrospun Plla/Collagen Nanofibrous Scaffold Coated With Chitosan to Sustain Release of Aloe Vera Gel for Skin Tissue Engineering}, journal = {Biomedical Engineering - Applications# Basis and Communications}, volume = {28}, number = {5}, pages = {-}, year = {2016} }
RIS	TY - JOUR AU - Salehi M AU - Farzamfar S AU - Bastami F AU - Tajerian R TI - Fabrication and Characterization of Electrospun Plla/Collagen Nanofibrous Scaffold Coated With Chitosan to Sustain Release of Aloe Vera Gel for Skin Tissue Engineering JO - Biomedical Engineering - Applications# Basis and Communications VL - 28 IS - 5 SP - EP - PY - 2016 ER -

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