Fabrication and Characterization of Electrospun Plla/Collagen Nanofibrous Scaffold Coated With Chitosan to Sustain Release of Aloe Vera Gel for Skin Tissue Engineering

Fabrication and Characterization of Electrospun Plla/Collagen Nanofibrous Scaffold Coated With Chitosan to Sustain Release of Aloe Vera Gel for Skin Tissue Engineering Publisher

Salehi M¹ ; Farzamfar S² ; Bastami F³ ; Tajerian R⁴

Show Affiliations

1. Department of Tissue Engineering and Cell Therapy, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran
2. Department of Medical Nanotechnology, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran
3. Research Institute of Dental Sciences, Dental School, Shahid Beheshti University of Medical Sciences, Tehran, Iran
4. Department of Tissue Engineering and Applied Cell Sciences, School of Advanced Technologies in Medicine, Tehran University of Medical Science, International Campus (TUMS-IC), Tehran, Iran

Source: Biomedical Engineering - Applications# Basis and Communications Published:2016

Abstract

Background and aim: Healing of fire-induced wounds has been still a challenge in clinical issues. The aim of this study was to fabricate a nanofibrous poly (L-lactic acid)/collagen (PLLA/COL) scaffold with sustained release of aloe vera (AV) gel using a chitosan (CT)-coated layer for skin tissue engineering applications. Material and methods: Morphology, porosity, tensile strength, hydrophilicity, degradation rate, water vapor permeability and water uptake ratio of the scaffold were characterized. The behaviors of mouse fibroblasts (L929) were evaluated on the scaffold. Results: We observed that although the porosity of the scaffold was decreased, other characteristics were enhanced by coating a CT layer. The scaffold supports attachment, viability and proliferation of mouse fibroblasts. Conclusion: Consequently, the PLLA/COL scaffold coated with CT for sustained release of AV gel can be considered as a desirable scaffold for skin tissue engineering. © 2016 National Taiwan University.

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4. Fabrication of Poly(L-Lactic Acid)/Chitosan Scaffolds by Solid-Liquid Phase Separation Method for Nerve Tissue Engineering: An in Vitro Study on Human Neuroblasts, Journal of Craniofacial Surgery (2019)

5. Study of Hybrid Alginate/Gelatin Hydrogel-Incorporated Niosomal Aloe Vera Capable of Sustained Release of Aloe Vera As Potential Skin Wound Dressing, Polymer Bulletin (2020)

6. An Investigation of Electrospun Henna Leaves Extract-Loaded Chitosan Based Nanofibrous Mats for Skin Tissue Engineering, Materials Science and Engineering C (2017)

7. Tissue Engineered Skin Substitutes, Advances in Experimental Medicine and Biology (2018)

8. A Bird's Eye View on the Use of Electrospun Nanofibrous Scaffolds for Bone Tissue Engineering: Current State-Of-The-Art, Emerging Directions and Future Trends, Nanomedicine: Nanotechnology# Biology# and Medicine (2016)

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Style	Citing Format
MLA	Salehi M, et al.. "Fabrication and Characterization of Electrospun Plla/Collagen Nanofibrous Scaffold Coated With Chitosan to Sustain Release of Aloe Vera Gel for Skin Tissue Engineering." Biomedical Engineering - Applications# Basis and Communications, vol. 28, no. 5, 2016, pp. -.
APA	Salehi M, Farzamfar S, Bastami F, Tajerian R (2016). Fabrication and Characterization of Electrospun Plla/Collagen Nanofibrous Scaffold Coated With Chitosan to Sustain Release of Aloe Vera Gel for Skin Tissue Engineering. Biomedical Engineering - Applications# Basis and Communications, 28(5), -.
Chicago	Salehi M, Farzamfar S, Bastami F, Tajerian R. "Fabrication and Characterization of Electrospun Plla/Collagen Nanofibrous Scaffold Coated With Chitosan to Sustain Release of Aloe Vera Gel for Skin Tissue Engineering." Biomedical Engineering - Applications# Basis and Communications 28, no. 5 (2016): -.
Harvard	Salehi M et al. (2016) 'Fabrication and Characterization of Electrospun Plla/Collagen Nanofibrous Scaffold Coated With Chitosan to Sustain Release of Aloe Vera Gel for Skin Tissue Engineering', Biomedical Engineering - Applications# Basis and Communications, 28(5), pp. -.
Vancouver	Salehi M, Farzamfar S, Bastami F, Tajerian R. Fabrication and Characterization of Electrospun Plla/Collagen Nanofibrous Scaffold Coated With Chitosan to Sustain Release of Aloe Vera Gel for Skin Tissue Engineering. Biomedical Engineering - Applications# Basis and Communications. 2016;28(5):-.
BibTex	@article{ author = {Salehi M and Farzamfar S and Bastami F and Tajerian R}, title = {Fabrication and Characterization of Electrospun Plla/Collagen Nanofibrous Scaffold Coated With Chitosan to Sustain Release of Aloe Vera Gel for Skin Tissue Engineering}, journal = {Biomedical Engineering - Applications# Basis and Communications}, volume = {28}, number = {5}, pages = {-}, year = {2016} }
RIS	TY - JOUR AU - Salehi M AU - Farzamfar S AU - Bastami F AU - Tajerian R TI - Fabrication and Characterization of Electrospun Plla/Collagen Nanofibrous Scaffold Coated With Chitosan to Sustain Release of Aloe Vera Gel for Skin Tissue Engineering JO - Biomedical Engineering - Applications# Basis and Communications VL - 28 IS - 5 SP - EP - PY - 2016 ER -

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