A-Esterase

A-Esterase Publisher

Adeli I^{1, 2} ; Mohammadsadeghi H^{1, 2} ; Bameri B^{1, 2}

Show Affiliations

1. Toxicology and Diseases Group (TDG), Pharmaceutical Sciences Research Center (PSRC), The Institute of Pharmaceutical Sciences (TIPS), Tehran, Iran
2. Department of Toxicology and Pharmacology, Faculty of Pharmacy, Tehran University of Medical Sciences (TUMS), Tehran, Iran

Source: Encyclopedia of Toxicology# Fourth Edition: Volume 1-9 Published:2023

Abstract

A-esterase enzymes, also called paraoxonase (PON), are a group of enzymes responsible for the metabolism and detoxification of different chemicals such as organophosphate insecticides and nerve gases. Three paraoxonase enzymes, PON1, PON2, and PON3, are produced in the human body. Although all three enzymes encoding genes are adjacently located on chromosomes, PON1 and PON3 are synthesized in the liver and released into the bloodstream, and PON2 is an intracellular enzyme found in several tissues. Apart from being engaged in the metabolism pathways of different compounds, PONs partake in the modulation of various diseases, including cardiovascular diseases, diabetes, and several neurological disorders. © 2024 Elsevier Inc. All rights reserved.

2. Can Hdl Cholesterol Be Replaced by Paraoxonase 1 Activity in the Prediction of Severe Coronary Artery Disease in Patients With Type 2 Diabetes?, Nutrition# Metabolism and Cardiovascular Diseases (2023)

3. Antioxidant Genes, the Insecticide Diazinon, and Toxicity, Toxicology: Oxidative Stress and Dietary Antioxidants (2020)

Experts (# of related papers)

Shokoufeh Hassani (1)

Mohammad Abdollahi (1)

Style	Citing Format
MLA	Adeli I, Mohammadsadeghi H, Bameri B. "A-Esterase." Encyclopedia of Toxicology# Fourth Edition: Volume 1-9, vol. 1, no. , 2023, pp. V1-189.
APA	Adeli I, Mohammadsadeghi H, Bameri B (2023). A-Esterase. Encyclopedia of Toxicology# Fourth Edition: Volume 1-9, 1(), V1-189.
Chicago	Adeli I, Mohammadsadeghi H, Bameri B. "A-Esterase." Encyclopedia of Toxicology# Fourth Edition: Volume 1-9 1, no. (2023): V1-189.
Harvard	Adeli I, Mohammadsadeghi H, Bameri B (2023) 'A-Esterase', Encyclopedia of Toxicology# Fourth Edition: Volume 1-9, 1(), pp. V1-189.
Vancouver	Adeli I, Mohammadsadeghi H, Bameri B. A-Esterase. Encyclopedia of Toxicology# Fourth Edition: Volume 1-9. 2023;1():V1-189.
BibTex	@article{ author = {Adeli I and Mohammadsadeghi H and Bameri B}, title = {A-Esterase}, journal = {Encyclopedia of Toxicology# Fourth Edition: Volume 1-9}, volume = {1}, number = {}, pages = {V1-189}, year = {2023} }
RIS	TY - JOUR AU - Adeli I AU - Mohammadsadeghi H AU - Bameri B TI - A-Esterase JO - Encyclopedia of Toxicology# Fourth Edition: Volume 1-9 VL - 1 IS - SP - V1 EP - 189 PY - 2023 ER -

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