The Prevalence, Awareness, and Treatment of Lipid Abnormalities in Iranian Adults: Surveillance of Risk Factors of Noncommunicable Diseases in Iran 2016 Publisher Pubmed



Aryan Z¹ ; Mahmoudi N¹ ; Sheidaei A² ; Rezaei S^{1, 3} ; Mahmoudi Z¹ ; Gohari K⁴ ; Rezaei N¹ ; Hajipour MJ^{1, 5} ; Dilmaghanimarand A¹ ; Razi F⁶ ; Sabooni M⁷ ; Kompani F⁸ ; Delavari A⁹ ; Larijani B¹⁰ Show All Authors
Source: Journal of Clinical Lipidology Published:2018

Abstract

Background: Hypercholesterolemia is one of the modifiable risk factors for atherosclerosis and cardiovascular diseases. Prevention and treatment of hypercholesterolemia and other lipid abnormalities require reliable data regarding the current prevalence of these abnormalities in the country. Objective: This study aims to determine the current prevalence, awareness, and treatment of lipid abnormalities in Iran. Methods: We planned to recruit 31,050 individuals who are 18 years old and above and take blood samples from individuals who are 25 years and above as representative sample at national and provincial levels in 2016. In practice, we recruited 21,293 Iranian adult aged more than 25 years through a systematic random sampling from 30 provinces of Iran. Sociodemographic, anthropometric, and lifestyle data and history of cardiometabolic diseases were gathered. Serum total cholesterol, high-density lipoprotein-cholesterol (HDL-C), triglyceride, low-density lipoprotein-cholesterol (LDL-C), and non–HDL-C were investigated. The prevalence of lipid abnormalities, awareness, treatment, and achievement to non–HDL-C and LDL-C goals were determined based on National Cholesterol Education Program Adult Treatment Panel III criteria. Results: In this representative Iranian adult population, 80.0% had at least one lipid abnormality, 69.2% had low HDL-C, 39.5% had high non–HDL-C, 28.0% had hypertriglyceridemia, and 26.7% hypercholesterolemia. Of those with hypercholesterolemia, 74.2% were aware of their lipid abnormality. Only 22.0% and 36.5% of the study population met the desired level of non–HDL-C and LDL-C, respectively. Conclusion: Low HDL-C is the main lipid abnormality in adult Iranian population. The majority of the population did not meet the desired level of non–HDL-C and LDL-C. Public health preventive policies should be made and implemented to better manage dyslipidemia. © 2018 National Lipid Association