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The Prevalence, Awareness, and Treatment of Lipid Abnormalities in Iranian Adults: Surveillance of Risk Factors of Noncommunicable Diseases in Iran 2016 Publisher Pubmed



Aryan Z1 ; Mahmoudi N1 ; Sheidaei A2 ; Rezaei S1, 3 ; Mahmoudi Z1 ; Gohari K4 ; Rezaei N1 ; Hajipour MJ1, 5 ; Dilmaghanimarand A1 ; Razi F6 ; Sabooni M7 ; Kompani F8 ; Delavari A9 ; Larijani B10 Show All Authors
Authors
  1. Aryan Z1
  2. Mahmoudi N1
  3. Sheidaei A2
  4. Rezaei S1, 3
  5. Mahmoudi Z1
  6. Gohari K4
  7. Rezaei N1
  8. Hajipour MJ1, 5
  9. Dilmaghanimarand A1
  10. Razi F6
  11. Sabooni M7
  12. Kompani F8
  13. Delavari A9
  14. Larijani B10
  15. Farzadfar F1
Show Affiliations
Authors Affiliations
  1. 1. Non-Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Students’ Scientific Research Center, Tehran University of Medical Sciences, Tehran, Iran
  4. 4. Department of Biostatistics, Faculty of Paramedical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  5. 5. Persian Gulf Marine Biotechnology Research Center, The Persian Gulf Biomedical Sciences Research Institute, Bushehr University of Medical Sciences, Bushehr, Iran
  6. 6. Diabetes Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran
  7. 7. Reference Health Laboratory, Ministry of Health and Medical Education, Tehran, Iran
  8. 8. Division of Hematology and Oncology, Children's Medical Center, Pediatrics Center of Excellence, Tehran University of Medical Sciences, Tehran, Iran
  9. 9. Digestive Oncology Research Center, Digestive Disease Research Institute, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran
  10. 10. Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran

Source: Journal of Clinical Lipidology Published:2018


Abstract

Background: Hypercholesterolemia is one of the modifiable risk factors for atherosclerosis and cardiovascular diseases. Prevention and treatment of hypercholesterolemia and other lipid abnormalities require reliable data regarding the current prevalence of these abnormalities in the country. Objective: This study aims to determine the current prevalence, awareness, and treatment of lipid abnormalities in Iran. Methods: We planned to recruit 31,050 individuals who are 18 years old and above and take blood samples from individuals who are 25 years and above as representative sample at national and provincial levels in 2016. In practice, we recruited 21,293 Iranian adult aged more than 25 years through a systematic random sampling from 30 provinces of Iran. Sociodemographic, anthropometric, and lifestyle data and history of cardiometabolic diseases were gathered. Serum total cholesterol, high-density lipoprotein-cholesterol (HDL-C), triglyceride, low-density lipoprotein-cholesterol (LDL-C), and non–HDL-C were investigated. The prevalence of lipid abnormalities, awareness, treatment, and achievement to non–HDL-C and LDL-C goals were determined based on National Cholesterol Education Program Adult Treatment Panel III criteria. Results: In this representative Iranian adult population, 80.0% had at least one lipid abnormality, 69.2% had low HDL-C, 39.5% had high non–HDL-C, 28.0% had hypertriglyceridemia, and 26.7% hypercholesterolemia. Of those with hypercholesterolemia, 74.2% were aware of their lipid abnormality. Only 22.0% and 36.5% of the study population met the desired level of non–HDL-C and LDL-C, respectively. Conclusion: Low HDL-C is the main lipid abnormality in adult Iranian population. The majority of the population did not meet the desired level of non–HDL-C and LDL-C. Public health preventive policies should be made and implemented to better manage dyslipidemia. © 2018 National Lipid Association
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