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Ribosome Profiling: A Useful Approach to Discover Hidden Corners of Sars-Cov-2 Publisher



Zandi M1 ; Behboudi E2 ; Zeinali P3 ; Soltani S1 ; Shojaei MR2
Authors
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Authors Affiliations
  1. 1. Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Department of Microbiology, School of Medicine, Golestan University of Medical Sciences, Gorgan, Iran
  3. 3. Department of Biochemistry and Biophysics, School of Medicine, Metabolic Disorders Research Center, Golestan University of Medical Sciences, Gorgan, Iran

Source: Cell Journal Published:2022


Abstract

Following SARS-CoV-2 China epidemic in the December 2019, researches have attended to the genome of novel coronavirus. Hidden corners of SARS-CoV-2, maybe a shiny way to discover its pathogenicity and virulence. To design therapeutic agents, it is critical to map the complete repertoire of viral-translated proteins. Ribosome profiling is considered as a snapshot of all active ribosomes in a cell at a specific time point. © 2022 Royan Institute (ACECR). All rights reserved.
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