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Recent Advances in Regenerative Medicine Strategies for Cancer Treatment Publisher Pubmed



Mansouri V1, 6 ; Beheshtizadeh N2, 3, 6 ; Gharibshahian M4, 6 ; Sabouri L6 ; Varzandeh M5, 6 ; Rezaei N7, 8, 9
Authors
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Authors Affiliations
  1. 1. Gene Therapy Research Center, Digestive Diseases Research Institute, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Department of Tissue Engineering and Applied Cell Sciences, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Iran
  3. 3. School of Engineering, Faculty of Science and Engineering, Macquarie University, Sydney, 2109, NSW, Australia
  4. 4. Department of Tissue Engineering, School of Medicine, Shahroud University of Medical Sciences, Shahroud, Iran
  5. 5. Department of Materials Engineering, Isfahan University of Technology, Isfahan, 84156-83111, Iran
  6. 6. Regenerative Medicine group (REMED), Universal Scientific Education and Research Network (USERN), Tehran, Iran
  7. 7. Research Center for Immunodeficiencies, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran
  8. 8. Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
  9. 9. Network of Immunity in Infection, Malignancy and Autoimmunity (NIIMA), Universal Scientific Education and Research Network (USERN), Tehran, Iran

Source: Biomedicine and Pharmacotherapy Published:2021


Abstract

Cancer stands as one of the most leading causes of death worldwide, while one of the most significant challenges in treating it is revealing novel alternatives to predict, diagnose, and eradicate tumor cell growth. Although various methods, such as surgery, chemotherapy, and radiation therapy, are used today to treat cancer, its mortality rate is still high due to the numerous shortcomings of each approach. Regenerative medicine field, including tissue engineering, cell therapy, gene therapy, participate in cancer treatment and development of cancer models to improve the understanding of cancer biology. The final intention is to convey fundamental and laboratory research to effective clinical treatments, from the bench to the bedside. Proper interpretation of research attempts helps to lessen the burden of treatment and illness for patients. The purpose of this review is to investigate the role of regenerative medicine in accelerating and improving cancer treatment. This study examines the capabilities of regenerative medicine in providing novel cancer treatments and the effectiveness of these treatments to clarify this path as much as possible and promote advanced future research in this field. © 2021
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