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Sars-Cov-2 and Covid-19, Basic and Clinical Aspects of the Human Pandemic: A Review



Zavvar M1, 2 ; Emadi Kochak H3 ; Abdolmohammadi K4 ; Rashidi N5, 6 ; Mokhtari M7 ; Noorbakhsh F2 ; Azadmanesh K8 ; Shamsi Gooshki E9 ; Fatahi Y10, 11 ; Mokhtari Azad T12 ; Jahangirifard A13 ; Mousavi MJ14 ; Masoumi E15, 16 ; Mirzaei HR2 Show All Authors
Authors
  1. Zavvar M1, 2
  2. Emadi Kochak H3
  3. Abdolmohammadi K4
  4. Rashidi N5, 6
  5. Mokhtari M7
  6. Noorbakhsh F2
  7. Azadmanesh K8
  8. Shamsi Gooshki E9
  9. Fatahi Y10, 11
  10. Mokhtari Azad T12
  11. Jahangirifard A13
  12. Mousavi MJ14
  13. Masoumi E15, 16
  14. Mirzaei HR2
  15. Gouya MM17
  16. Rezaei F17
  17. Nicknam MH2, 18
Show Affiliations
Authors Affiliations
  1. 1. Department of Medical Laboratory Sciences, School of Allied Medical Sciences, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Department of Infectious Diseases, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
  4. 4. Department of Medical Laboratory Sciences, Sari Branch, Islamic Azad University, Sari, Iran
  5. 5. Department of Immunology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran
  6. 6. Immunology Research Center, Iran University of Medical Sciences, Tehran, Iran
  7. 7. Department of Medicine, Pulmonary & Critical Care Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  8. 8. Department of Virology, Pasteur Institute of Iran, Tehran, Iran
  9. 9. Medical Ethics and History of Medicine Research Center, Tehran University of Medical Sciences, Tehran, Iran
  10. 10. Department of Pharmaceutical Nanotechnology, School of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
  11. 11. Nanotechnology Research Center, School of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
  12. 12. Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
  13. 13. Lung Transplantation Research Center, National Research Institute of Tuberculosis and Lung Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  14. 14. Department of Hematology, School of Allied Medicine, Bushehr University of Medical Sciences, Bushehr, Iran
  15. 15. Department of Medical Immunology, School of Medicine, Ilam University of Medical Sciences, Ilam, Iran
  16. 16. Zoonotic Diseases Research Center, Ilam University of Medical Sciences, Ilam, Iran
  17. 17. Communicable Disease Control Centre, Ministry of Health and Medical Education, Tehran, Iran
  18. 18. Molecular Immunology Research Center, Tehran University of Medical Sciences, Tehran, Iran

Source: Iranian Journal of Public Health Published:2021

Abstract

In the last two decades, we have witnessed three major epidemics of the coronavirus human disease namely, severe acute respiratory syndrome (SARS), Middle Eastern respiratory syndrome, and more recently an ongoing global pandemic of coronavirus disease 2019 (COVID-19). Iran, a country of nearly 84 million, in the Middle East, severely in-volved with the COVID-19 disease. A documented multidimensional approach to COVID-19 disease is therefore man-datory to provide a well-balanced platform for the concerned medical community in our county and beyond. In this review, we highlight the disease status in Iran and attempt to provide a multilateral view of the fundamental and clinical aspects of the disease including the clinical features of the confirmed cases, virology, pathogenesis, epidemiology, and laboratory methods needed for diagnosis. © 2021 Zavvar et al. Publish.
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