The Effect of a Calcium Pre-Rinse on the Salivary and Plaque Fluoride and Calcium Concentrations After a 900 Ppm Naf Rinse: A Placebo-Controlled Randomized Clinical Trial



Ramazani N¹ ; Saadatfar N² ; Mahvi AH^{3, 4} ; Ramazani M⁵
Source: Fluoride Published:2018

Abstract

The amount of available calcium delivered to plaque is dependent on the use of calcium compounds. This study assessed the salivary and plaque concentrations of the fluoride ion [F] and the calcium ion [Ca] after the use of a calcium pre-rinse. Thirty subjects completed this double-blind crossover trial in a dormitory in Zahedan, Iran. The subjects were recruited using a table of random numbers. After prophylaxis and two weeks of oral hygiene practices using non-fluoride products, 15 subjects, chosen randomly, rinsed with calcium placebo/sodium fluoride and the other 15 subjects rinsed with calcium lactate/sodium fluoride. One and 12 hours later, salivary and plaque samples were collected. After another prophylaxis and the elapse of a further two weeks, with the previous conditions of oral hygiene using non-fluoride products, the participants rinsed with the treatment that they had not previously used. After 1 and 12 hours, sampling was again done. The [F] and [Ca] were analyzed using a fluoride electrode and atomic absorption spectrometry, respectively. The data were analyzed using repeated measures ANOVA at a significance level of 5%. The 1 and 12 hour salivary [F] were significantly higher after the calcium and fluoride rinses (p<0.001). No significant difference was found in the plaque [F] between the two rinse treatments (p>0.05). A significant difference was detected in the plaque [F] when comparing the values obtained at different times with each treatment (p<0.001). With respect to the salivary and plaque [Ca], there was no significant difference in the values obtained at the different times for each treatment, regardless of whether the rinse was with calcium or calcium placebo (p>0.05). The salivary [F] increased with the calcium and fluoride rinsing. Our attempts to increase the salivary [Ca] and plaque [F] and [Ca], by using a calcium pre-rinse met with no success. © 2018, ISFR.