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Case Report: First Coinfection Report of Mixed Leishmania Infantum/Leishmania Major and Human Immunodeficiency Virus-Acquired Immune Deficiency Syndrome: Report of a Case of Disseminated Cutaneous Leishmaniasis in Iran Publisher Pubmed



Badirzadeh A1 ; Mohebali M2, 3 ; Sabzevari S4 ; Ghafoori M5 ; Arzamani K4 ; Seyyedin M6 ; Hashemi SA4
Authors
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Authors Affiliations
  1. 1. Department of Medical Parasitology and Mycology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  2. 2. Department of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Center for Research of Endemic Parasites of Iran, Tehran University of Medical Sciences, Tehran, Iran
  4. 4. Vector-Born Research Center, North Khorasan University of Medical Science, Bojnurd, Iran
  5. 5. North Khorasan University of Medical Sciences, Bojnurd, Iran
  6. 6. Razi Vaccine and Serum Research Institute, Taleghani Street, Mashhad, Iran

Source: American Journal of Tropical Medicine and Hygiene Published:2018


Abstract

Visceral leishmaniasis, a neglected tropical disease, is the third most common opportunistic disease in immunosuppressed patients, such as those affected by the human immunodeficiency virus (HIV)/acquired immune deficiency syndrome. Although the reports have been characterized as Leishmania/HIV coinfections, the occurrence of a mixed infection by two Leishmania species in HIV-positive patients is rare. Here, we present an atypical case of disseminated cutaneous leishmaniasis (DCL) in a 26-year-old HIV-positive man. The diagnosis ofDCLwas established using skin biopsy and histopathology examinations and confirmed bymolecular techniques. This is the first case of a Leishmania/HIV coinfection due to a mixed infection of Leishmania infantum/Leishmania major in Iran. © 2018 by The American Society of Tropical Medicine and Hygiene.
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