Tehran University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Determination of Antimicotic Susceptibility Pattern of Candida Species Isolated From Patients With Symptomatic Candiduria Publisher



Barati M1, 2 ; Mirkalantari S3, 4 ; Ansari S5 ; Salari S6, 7 ; Fattahi A8
Authors
Show Affiliations
Authors Affiliations
  1. 1. Research Center of Pediatric Infectious Diseases, Institute of Immunology and Infectious Diseases, Iran University of Medical Sciences, Tehran, Iran
  2. 2. Department of Infectious Disease, Rasul-e Akram Hospital, Iran University of Medical Sciences, Tehran, Iran
  3. 3. Department of Microbiology, Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran
  4. 4. Microbiol Biotechnology Research Center, Iran University of Medical Sciences, Tehran, Iran
  5. 5. Department of Parasitology and Mycology, School of Medicine, Shahid Beheshti University of Medical Scienses, Tehran, Iran
  6. 6. Student Research Committee, Kerman University of Medical Sciences, Kerman, Iran
  7. 7. Department of Medical Mycology and Parasitology, School of Medicine, Medical University of Kerman, Kerman, Iran
  8. 8. Center for Research and Training in Skin Disease and Leprosy, Tehran University of Medical Sciences, Tehran, Iran

Source: Journal of Research in Medical Sciences Published:2019


Abstract

Background: The present study was conducted to determine antimicotic susceptibility of Candida species (sp.) from patients with symptomatic candiduria. Materials and Methods: Identification of Candida sp. and determination of efficacy of most routine antifungals were done using polymerase chain reaction-restriction fragment length polymorphism method and E-test, respectively. Results: The results from susceptibility test reveal that caspofungin and amphotericin B have high antifungal activity against both albicans (100% and 96%, respectively) and nonalbicans (95.11% and 72.72%, respectively) isolates. Conclusion: The present study suggests that caspofungin and amphotericin B have the excellent ability to eradicate both Candida groups that showed decreased susceptibility to other compounds. © 2019 Wolters Kluwer Medknow Publications. All rights reserved.
Related Docs
1. Epidemiologic and Antifungal Susceptibility Profile of Candiduria Among Patients Hospitalized in the Nephrology and Intensive Care Unit Wards, Tehran, Iran, Jundishapur Journal of Microbiology (2022)
2. Azole Antifungal Resistance in Candida Albicans and Candida Glabrata Isolated From Vulvovaginal Candidiasis Patients, Archives of Clinical Infectious Diseases (2021)
Experts (# of related papers)
Seyed Jamal Hashemi Hezaveh (1)