A Nanodevice Based on Graphene Oxide for the Direct Determination of Gabapentin in Spiked Saliva and Serum Samples

A Nanodevice Based on Graphene Oxide for the Direct Determination of Gabapentin in Spiked Saliva and Serum Samples Publisher

Jalilzadeh H ; Feyzibarnaji B ; Mohammadi A ; Amanlou M ; Mohebbi N

Source: Journal of Analytical Chemistry Published:2026

Abstract

Abstract: Gabapentin (GB) is commonly used as an anti-epilepsy medication. Electrochemical sensing has been shown to be a promising method for drug detection at very low concentrations. In the present study, for the first time, electrochemical detection of GB was directly conducted using a modified glassy carbon electrode based on graphene oxide and gold nanoparticles. The limit of detection and limit of quantitation of the method were found to be 0.08 and 0.24 μM, respectively, by means of the differential pulse voltammetry technique. The sensor was characterized via scanning electron microscopy, energy-dispersive X-ray spectroscopy, and transmission electron microscopy. The reproducibility, selectivity, stability, and repeatability of the modified electrode were found to be acceptable. The developed modified electrode demonstrated excellent performance for the detection of GB in standard solutions as well as in serum and saliva samples. © Pleiades Publishing, Ltd. 2026.

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Fatemeh Nili Ahmadabadi (1)

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Style	Citing Format
MLA	Jalilzadeh H, et al.. "A Nanodevice Based on Graphene Oxide for the Direct Determination of Gabapentin in Spiked Saliva and Serum Samples." Journal of Analytical Chemistry, vol. 81, no. 2, 2026, pp. 356-365.
APA	Jalilzadeh H, Feyzibarnaji B, Mohammadi A, Amanlou M, Mohebbi N (2026). A Nanodevice Based on Graphene Oxide for the Direct Determination of Gabapentin in Spiked Saliva and Serum Samples. Journal of Analytical Chemistry, 81(2), 356-365.
Chicago	Jalilzadeh H, Feyzibarnaji B, Mohammadi A, Amanlou M, Mohebbi N. "A Nanodevice Based on Graphene Oxide for the Direct Determination of Gabapentin in Spiked Saliva and Serum Samples." Journal of Analytical Chemistry 81, no. 2 (2026): 356-365.
Harvard	Jalilzadeh H et al. (2026) 'A Nanodevice Based on Graphene Oxide for the Direct Determination of Gabapentin in Spiked Saliva and Serum Samples', Journal of Analytical Chemistry, 81(2), pp. 356-365.
Vancouver	Jalilzadeh H, Feyzibarnaji B, Mohammadi A, Amanlou M, Mohebbi N. A Nanodevice Based on Graphene Oxide for the Direct Determination of Gabapentin in Spiked Saliva and Serum Samples. Journal of Analytical Chemistry. 2026;81(2):356-365.
BibTex	@article{ author = {Jalilzadeh H and Feyzibarnaji B and Mohammadi A and Amanlou M and Mohebbi N}, title = {A Nanodevice Based on Graphene Oxide for the Direct Determination of Gabapentin in Spiked Saliva and Serum Samples}, journal = {Journal of Analytical Chemistry}, volume = {81}, number = {2}, pages = {356-365}, year = {2026} }
RIS	TY - JOUR AU - Jalilzadeh H AU - Feyzibarnaji B AU - Mohammadi A AU - Amanlou M AU - Mohebbi N TI - A Nanodevice Based on Graphene Oxide for the Direct Determination of Gabapentin in Spiked Saliva and Serum Samples JO - Journal of Analytical Chemistry VL - 81 IS - 2 SP - 356 EP - 365 PY - 2026 ER -

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