Detailed Analysis of Total Colectomy on Health-Related Quality of Life in Adult Patients With Ulcerative Colitis

Detailed Analysis of Total Colectomy on Health-Related Quality of Life in Adult Patients With Ulcerative Colitis Publisher

Aghdaei HA¹ ; Ghasemi F¹ ; Nooraliee M¹ ; Fazeli MS² ; Anaraki F³ ; Sorrentino D⁴ ; Balaii H¹ ; Shahrokh S⁵

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1. Basic and Molecular Epidemiology of Gastrointestinal Disorders Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran
2. Department of surgery, Imam Khomeini Medical complex, Tehran University of Medical Sciences, Tehran, Iran
3. Colorectal Division of Department of Surgery, Taleghani Hospital, Shahid Beheshti University of Medical Sciences, Tehran, 19835-178, Iran
4. IBD Center, Department of Medicine, Division of Gastroenterology, Virginia Tech Carilion School of Medicine, Roanoke, VA, United States
5. Gastroenterology and Liver Diseases Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran

Source: Gastroenterology and Hepatology from Bed to Bench Published:2017

Abstract

Aim: The aim of this study was to explore the quality of life (QoL) in a group of patients who had an intractable disease on medical therapy including biologics and underwent surgery. Background: Quality of life of patients with ulcerative colitis (UC) has been measured with a series of multiple questionnaires Methods: An observational cross sectional study was carried out on 68 patients with documented UC referring to an IBD clinic in a tertiary hospital. Patients with UC who had a colectomy because of intractable disease and were in remission for a year were eligible for enrollment Patients were instructed to fill the SF-36 Questionnaire (interviewer-administered) regarding quality of life. Side effects were evaluated with another questionnaire. Results were compared with the normal population of the community. Results: In comparison with normal population, patients having colectomy have better general QoL. Impotency and incontinency were most common adverse events after colectomy while the adverse events that decreased the QoL significantly were anal secretions and number of bowel movements per day without using antidiarrheal- drugs. Conclusion: In conclusion, our study showed a significant improvement of general QoL in a selected group of UC patients, who were in clinical remission following IPAA and only number of bowel movements per day and anal secretions significantly impaired their QoL. We suggest that a disease-specific questionnaire should be designed, making changes in health-related QOL more detectable over time, since it is more sensitive to these changes in IBD patients than a general questionnaire. © 2017 RIGLD, Research Institute for Gastroenterology and Liver Diseases.

Style	Citing Format
MLA	Aghdaei HA, et al.. "Detailed Analysis of Total Colectomy on Health-Related Quality of Life in Adult Patients With Ulcerative Colitis." Gastroenterology and Hepatology from Bed to Bench, vol. 10, no. , 2017, pp. S27-S32.
APA	Aghdaei HA, Ghasemi F, Nooraliee M, Fazeli MS, Anaraki F, Sorrentino D, Balaii H, Shahrokh S (2017). Detailed Analysis of Total Colectomy on Health-Related Quality of Life in Adult Patients With Ulcerative Colitis. Gastroenterology and Hepatology from Bed to Bench, 10(), S27-S32.
Chicago	Aghdaei HA, Ghasemi F, Nooraliee M, Fazeli MS, Anaraki F, Sorrentino D, Balaii H, Shahrokh S. "Detailed Analysis of Total Colectomy on Health-Related Quality of Life in Adult Patients With Ulcerative Colitis." Gastroenterology and Hepatology from Bed to Bench 10, no. (2017): S27-S32.
Harvard	Aghdaei HA et al. (2017) 'Detailed Analysis of Total Colectomy on Health-Related Quality of Life in Adult Patients With Ulcerative Colitis', Gastroenterology and Hepatology from Bed to Bench, 10(), pp. S27-S32.
Vancouver	Aghdaei HA, Ghasemi F, Nooraliee M, Fazeli MS, Anaraki F, Sorrentino D, et al.. Detailed Analysis of Total Colectomy on Health-Related Quality of Life in Adult Patients With Ulcerative Colitis. Gastroenterology and Hepatology from Bed to Bench. 2017;10():S27-S32.
BibTex	@article{ author = {Aghdaei HA and Ghasemi F and Nooraliee M and Fazeli MS and Anaraki F and Sorrentino D and Balaii H and Shahrokh S}, title = {Detailed Analysis of Total Colectomy on Health-Related Quality of Life in Adult Patients With Ulcerative Colitis}, journal = {Gastroenterology and Hepatology from Bed to Bench}, volume = {10}, number = {}, pages = {S27-S32}, year = {2017} }
RIS	TY - JOUR AU - Aghdaei HA AU - Ghasemi F AU - Nooraliee M AU - Fazeli MS AU - Anaraki F AU - Sorrentino D AU - Balaii H AU - Shahrokh S TI - Detailed Analysis of Total Colectomy on Health-Related Quality of Life in Adult Patients With Ulcerative Colitis JO - Gastroenterology and Hepatology from Bed to Bench VL - 10 IS - SP - S27 EP - S32 PY - 2017 ER -

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