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Overview of Herbal and Traditional Remedies in the Treatment of Cutaneous Leishmaniasis Based on Traditional Persian Medicine Publisher Pubmed



Parvizi MM1 ; Zare F2 ; Handjani F1, 3 ; Nimrouzi M4 ; Zarshenas MM5, 6, 7
Authors
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Authors Affiliations
  1. 1. Molecular Dermatology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
  2. 2. Department of History of Medicine, School of Traditional Medicine, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Department of Dermatology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran
  4. 4. Department of Traditional Persian Medicine, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran
  5. 5. Department of Phytopharmaceuticals (Traditional Pharmacy), School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran
  6. 6. Medicinal Plants Processing Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
  7. 7. Epilepsy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran

Source: Dermatologic Therapy Published:2020


Abstract

This study aims to describe the herbal and traditional remedies in the treatment of cutaneous leishmaniasis (CL) with an overview on related available evidence in modern medicine. This study is a review that focuses on the most important Traditional Persian Medicine (TPM) sources including Avicenna's Canon of Medicine, Jorjani's Zakhira-yi Kharazmshahi, and Aazam-Khan's Eksir-e-Aazam, as well as pertinent information from Embase, PubMed, Scopus, Scientific Information Database, and Google Scholar by using the keywords salak, rish-e-balkhi, cutaneous leishmaniasis, and leishmaniasis for selected remedies. Several oral and topical herbal remedies, such as Vitis vinifera L. (Unripe grapes), Berberis vulgaris L., Rheum ribes L., Santalum album L., Cinnamomum camphora (L.) J.Presl (Camphor), Brassica nigra (L.) K. Koch, Crocus sativus L., Juniperus excelsa M. Bieb, honey, and Alum root, were mentioned in TPM resources for the treatment of CL. Furthermore, cauterization, cupping, and leech therapy were considered for this purpose. In this review, some evidence-based studies will also be presented that have demonstrated the therapeutic properties of some of these products. In conclusion, the sages of TPM have recommended several systemic or topical medications, in addition to physical procedures, for treatment of CL, all of which could be a base for conducting further research on its efficacy. © 2020 Wiley Periodicals LLC.