Tehran University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Exposure to Ambient Air Pollution and Risk of Childhood Cancers: A Population-Based Study in Tehran, Iran Publisher Pubmed



Seifi M1 ; Niazi S1, 2 ; Johnson G2 ; Nodehi V3 ; Yunesian M4, 5
Authors
Show Affiliations
Authors Affiliations
  1. 1. Department of Environmental Health Engineering, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. International Laboratory for Air Quality and Health, Queensland University of Technology (QUT), Brisbane, Australia
  3. 3. Department of geography, Kharazmi University, Tehran, Iran
  4. 4. Center for Air Pollution Research (CAPR), Institute for Environmental Research (IER), Tehran University of Medical Sciences, Tehran, Iran
  5. 5. Department of Research Methodology and Data Analysis, Institute for Environmental Research, Tehran University of Medical Sciences, Tehran, Iran

Source: Science of the Total Environment Published:2019


Abstract

The relationship between air pollution and childhood cancer is inconclusive. We investigated the associations between exposure to ambient air pollution and childhood cancers in Tehran, Iran. This project included children between 1 and 15 years-of-age with a cancer diagnosis by the Center for the Control of Non Communicable Disease (n = 161) during 2007 to 2009. Controls were selected randomly within the city using a Geographic Information System (GIS) (n = 761). The cases were geocoded based on exact home addresses. Air pollution exposure of cases and random controls were estimated by a previously developed Land Use Regression (LUR) model for the 2010 calendar year. The annual mean concentrations of Particulate Matter ≤ 10 μm (PM 10 ), nitrogen dioxide (NO 2 ) and sulfur dioxide (SO 2 ) in the locations of cancer cases were 101.97 μg/m 3 , 49.42 ppb and 38.92 ppb respectively, while in the random control group, respective mean exposures were 98.63 μg/m 3 , 45.98 ppb and 38.95 ppb. A logistic regression model was used to find the probability of childhood cancer per unit increase in PM 10 , NO 2 and SO 2 . We observed a positive association between exposures to PM 10 with childhood cancers. We did, however, observe a positive, but not statistically significant association between NO 2 exposure and childhood cancer. Our study is the first to highlight an association between air pollution exposure and childhood cancer risk in Iran, however these findings require replication through future studies. © 2018
Related Docs
View other Related Docs
1. Long-Term Trends and Health Impact of Pm2.5 and O3 in Tehran, Iran, 2006–2015, Environment International (2018)
2. Land Use Regression Models for Alkylbenzenes in a Middle Eastern Megacity: Tehran Study of Exposure Prediction for Environmental Health Research (Tehran Sepehr), Environmental Science and Technology (2017)
3. A Systematic Review of Land Use Regression Models for Volatile Organic Compounds, Atmospheric Environment (2017)
4. Annual and Seasonal Spatial Models for Nitrogen Oxides in Tehran, Iran, Scientific Reports (2016)
5. Short-Term Associations Between Daily Mortality and Ambient Particulate Matter, Nitrogen Dioxide, and the Air Quality Index in a Middle Eastern Megacity, Environmental Pollution (2019)
6. Long-Term Exposure to Ambient Air Pollution and Autism Spectrum Disorder in Children: A Case-Control Study in Tehran, Iran, Science of the Total Environment (2018)
7. Spatiotemporal Description of Btex Volatile Organic Compounds in a Middle Eastern Megacity: Tehran Study of Exposure Prediction for Environmental Health Research (Tehran Sepehr), Environmental Pollution (2017)
8. Examining the Relationship Between Land Use and Childhood Leukemia and Lymphoma in Tehran, Scientific Reports (2024)
Experts (# of related papers)
View all Related Experts
Masoud Yunesian (13)
Mohammad Sadegh Hassanvand (9)
Other Related Docs
9. Comparison of Pm2.5 Around 1893 Elementary Schools and Kindergartens in Tehran Over Different Time Windows, Urban Climate (2025)
10. Estimation of Mortality Attributed to Pm2.5 and Co Exposure in Eight Industrialized Cities of Iran During 2011, Iran Occupational Health (2016)
11. Maternal Exposure to Air Pollutants and Birth Weight in Tehran, Iran, Journal of Environmental Health Science and Engineering (2019)
12. Mortality and Morbidity Due to Exposure to Outdoor Air Pollution in Mashhad Metropolis, Iran. the Airq Model Approach, Environmental Research (2016)
13. Association of Ambient Air Pollution and Age at Menopause: A Population-Based Cohort Study in Tehran, Iran, Air Quality# Atmosphere and Health (2022)
14. Characterization of Pahs and Metals in Indoor/Outdoor Pm10/Pm2.5/Pm1 in a Retirement Home and a School Dormitory, Science of the Total Environment (2015)
15. Estimation of Short-Term Mortality and Morbidity Attributed to Fine Particulate Matter in the Ambient Air of Eight Iranian Cities, Annals of Global Health (2018)
16. Spatial Homogeneity and Heterogeneity of Ambient Air Pollutants in Tehran, Science of the Total Environment (2019)
17. Airborne Particulate Matter in Tehran’S Ambient Air, Journal of Environmental Health Science and Engineering (2021)
18. National and Sub-National Age-Sex Specific and Cause-Specific Mortality and Disability-Adjusted Life Years (Dalys) Attributable to Household Air Pollution From Solid Cookfuel Use (Hap) in Iran, 1990–2013, Environmental Research (2017)
19. Source Apportionment of Ambient Pm2.5 in Two Locations in Central Tehran Using the Positive Matrix Factorization (Pmf) Model, Science of the Total Environment (2018)
20. Equity Chasm in Megacities: Five Leading Causes of Death in Tehran, Archives of Iranian Medicine (2015)
21. Epigenetic Alterations and Exposure to Air Pollutants: Protocol for a Birth Cohort Study to Evaluate the Association Between Adverse Birth Outcomes and Global Dna Methylation, JMIR Research Protocols (2017)
22. National and Sub-National Exposure to Ambient Fine Particulate Matter (Pm2.5) and Its Attributable Burden of Disease in Iran From 1990 to 2016, Environmental Pollution (2019)
23. Cutaneous Leishmaniasis Prevalence and Morbidity Based on Environmental Factors in Ilam, Iran: Spatial Analysis and Land Use Regression Models, Acta Tropica (2016)
24. Association of Systemic Inflammation and Coagulation Biomarkers With Source-Specific Pm2.5 Mass Concentrations Among Young and Elderly Subjects in Central Tehran, Journal of the Air and Waste Management Association (2021)