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An Algorithmic Approach to Multisystem Inflammatory Syndrome in Children With Covid-19: Tehran Children’S Medical Center Protocol Publisher



Ziaee V1, 2, 3 ; Assari R1, 2 ; Mamishi S2, 4, 5 ; Zeinaloo A2, 6 ; Mohammadpour M2, 7 ; Malekzadeh I2, 8 ; Tahghighi F1, 2 ; Sadeghi P1, 9 ; Mousavi MS1, 2 ; Raeeskarami SR1, 10 ; Eshaghi H2, 4 ; Khodabandeh M2, 4 ; Abdosalehi M2, 4 ; Moghadam EA2, 6 Show All Authors
Authors
  1. Ziaee V1, 2, 3
  2. Assari R1, 2
  3. Mamishi S2, 4, 5
  4. Zeinaloo A2, 6
  5. Mohammadpour M2, 7
  6. Malekzadeh I2, 8
  7. Tahghighi F1, 2
  8. Sadeghi P1, 9
  9. Mousavi MS1, 2
  10. Raeeskarami SR1, 10
  11. Eshaghi H2, 4
  12. Khodabandeh M2, 4
  13. Abdosalehi M2, 4
  14. Moghadam EA2, 6
  15. Zanjani KS2, 6
  16. Gorji M2, 6
  17. Shabanian R2, 6
  18. Rad EM2, 6
  19. Yaghmaei B2, 7
  20. Sharifzadeh M2, 7
  21. Majnoon MT2, 6
  22. Hassani A2, 7
  23. Najafi Z2, 7
  24. Tahernia L2, 7
  25. Asadabadi M2, 8
  26. Memarian S2, 8
  27. Memar EH2, 8
  28. Sadeghirad P2, 8
  29. Soti M2, 8
  30. Mohamadi M2, 8
  31. Sharifi P2, 8
Show Affiliations
Authors Affiliations
  1. 1. Rheumatology Subgroup, Department of Pediatrics, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Children’s Medical Center, Pediatrics Center of Excellence, Tehran, Iran
  3. 3. Pediatric Rheumatology Research Group, Rheumatology Research Center, Tehran University of Medical Science, Tehran, Iran
  4. 4. Infectious Diseases Subgroup, Department of Pediatrics, Tehran University of Medical Sciences, Tehran, Iran
  5. 5. Pediatrics Infectious Diseases Research Center, Tehran University of Medical Sciences, Tehran, Iran
  6. 6. Cardiology Subgroup, Department of Pediatrics, Tehran University of Medical Sciences, Tehran, Iran
  7. 7. Intensive Care Subgroup, Department of Pediatrics, Tehran University of Medical Sciences, Tehran, Iran
  8. 8. Emergency Subgroup, Department of Pediatrics, Tehran University of Medical Sciences, Tehran, Iran
  9. 9. Bahrami Children’s Hospital, Tehran, Iran
  10. 10. Imam Khomeini Complex Hospital, Tehran, Iran

Source: Iranian Journal of Pediatrics Published:2020


Abstract

COVID-19 as a viral infection is usually asymptomatic in children, but complication of this disease in children is not rare and may be fatal. Hyper inflammation of COVID-19 is a potential fatal in undiagnosed children. It is very similar to Kawasaki disease but with higher mortality and morbidity. Multisystem inflammatory syndrome in children (MIS-C) and multi-organ involvement was reported in hyper inflammation syndrome following COVID19. Herein we report our algorithmic approach to Kawasaki-like syndromes due to COVID-19 in our center. Based-on this approach we had no mortality during the last 5 months. © 2020, Author(s).
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