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Diagnostic and Prognostic Value of Routine Blood Tests in Patients With Covid-19 in Iran, Tehran Publisher



Asanjarani B1 ; Siri G1 ; Hosseini SME1 ; Abdollahi H2 ; Hasibi M1 ; Erfanian R3 ; Hosseini MME1 ; Alesaeidi S4 ; Asadollahiamin A5
Authors
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Authors Affiliations
  1. 1. Department of Internal Medicine, Amir Alam Hospital, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Department of Anesthesiology, Amir Alam Hospital, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Department of Ear, Nose and Throat (ENT) Diseases, Amir Alam Hospital, Tehran University of Medical Sciences, Tehran, Iran
  4. 4. Rheumatology Research Center, Tehran University of Medical Sciences, Tehran, Iran
  5. 5. Iranian Research Center for HIV/AIDS, Iranian Institute for Reduction of High-Risk Behaviors, Tehran University of Medical Sciences, Tehran, Iran

Source: Journal of Iranian Medical Council Published:2021


Abstract

Background: Routine blood testing consists of Complete Blood Count (CBC) indices together with Comprehensive Metabolic Panel (CMP) which have significant roles in both diagnosis and prognosis of the novel coronavirus disease 2019 (COVID-19). Methods: A total number of 942 COVID-19 patients and 400 healthy persons as the control group were enrolled in this study. All patients were admitted to a single center and were divided into two groups according to disease severity (severe or non-severe). Routine laboratory findings of peripheral blood sample were collected and then analyzed. Results: Neutrophil-Lymphocyte Ratio (NLR) had the highest sensitivity and specificity value for COVID-19 diagnosis. Among patients with different severities of COVID-19, the amount of neutrophil, NLR, platelet, hemoglobin, Red cell Distribution Width (RDW) and total bilirubin was significantly different (p<0.01). Conclusion: Some indices of complete blood count and comprehensive metabolic panel have diagnostic and prognostic roles in COVID-19 patients, which are helpful in early diagnosis, predicting severity and adverse outcomes of patients with COVID-19. © 2021 Islamic Republic of Iran Medical Council. All Rights Reserved.
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