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Synthesis and Anti-Acetylcholinesterase Activity of N-[(Indolyl)Ethyl)- Coumarin-Yloxy)]Alkanamides Publisher



Ghaneinasab S1 ; Nadri H2 ; Moradi A2 ; Marjani A1 ; Shabani S3 ; Firoozpour L4 ; Moghimi S4 ; Khoobi M3, 5 ; Hadizadeh F6 ; Foroumadi A3, 7
Authors
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Authors Affiliations
  1. 1. Department of Chemistry, Arak Branch, Islamic Azad University, Arak, Iran
  2. 2. Department of Medicinal Chemistry, Faculty of Pharmacy, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
  3. 3. Department of Medicinal Chemistry, Faculty of Pharmacy, Pharmaceutical Sciences Research Center, Tehran University of Medical Sciences, Tehran, Iran
  4. 4. Drug Design and Development Research Center, Tehran University of Medical Sciences, Tehran, Iran
  5. 5. Department of Pharmaceutical Biomaterials, Medical Biomaterials Research Center, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
  6. 6. Biotechnology Research Center, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran
  7. 7. Department of Medicinal Chemistry, Faculty of Pharmacy, Neuroscience Research Center, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman, Iran

Source: Journal of Chemical Research Published:2017


Abstract

Novel coumarin-tryptamine systems attached through a linker were synthesised and evaluated in vitro against acetylcholinesterase by the classical Ellman's test. © 2017, Science Reviews 2000 Ltd. All rights reserved.