A Case Presentation of Voriconazole Therapy in a Brochopulmonary Dysplasia

A Case Presentation of Voriconazole Therapy in a Brochopulmonary Dysplasia

Amini E¹ ; Nili F¹ ; Nayeri F¹ ; Esmaeilnia T² ; Dalili H² ; Shariat M³

Show Affiliations

1. Maternal, Fetal and Neonatal Research Center, Tehran University of Medical Sciences, Tehran, Iran
2. Breastfeeding Research Center, Tehran University of Medical Sciences, Tehran, Iran
3. Maternal, Fetal And, Neonatal Research Center, Tehran University of Medical Sciences, Tehran, Iran

Source: Iranian Journal of Neonatology Published:2015

Abstract

Premature infants may be more vulnerable to fungal infections because of their immature immune system, poorly developed epithelial skin and mucosal barriers, and the high rate of invasive procedures, such as central venous catheters and intubation, which compromise host defenses (e.g. skin integrity). Voriconazole is a newer systemic antifungal agent effective against Candida and Aspergillus. There are few reports of its safe use in newborns. We report the first case report-a 29 gestational age-900 gram baby girl of safe Voriconazole use in a critically ill with profound pancytopenia-huge hepatosplenomegaly due to fungal infection resistant to amphotericin B. with beginning oral Voriconazole all liver functions tests what were severely abnormal returned normal with normalizing of the size of liver and spleen. It was noted to be safe and well tolerated by the newborn. Because of oral administration of it, voriconazole is a very good choice for fungal infections in neonates.

Style	Citing Format
MLA	Amini E, et al.. "A Case Presentation of Voriconazole Therapy in a Brochopulmonary Dysplasia." Iranian Journal of Neonatology, vol. 6, no. 1, 2015, pp. 33-34.
APA	Amini E, Nili F, Nayeri F, Esmaeilnia T, Dalili H, Shariat M (2015). A Case Presentation of Voriconazole Therapy in a Brochopulmonary Dysplasia. Iranian Journal of Neonatology, 6(1), 33-34.
Chicago	Amini E, Nili F, Nayeri F, Esmaeilnia T, Dalili H, Shariat M. "A Case Presentation of Voriconazole Therapy in a Brochopulmonary Dysplasia." Iranian Journal of Neonatology 6, no. 1 (2015): 33-34.
Harvard	Amini E et al. (2015) 'A Case Presentation of Voriconazole Therapy in a Brochopulmonary Dysplasia', Iranian Journal of Neonatology, 6(1), pp. 33-34.
Vancouver	Amini E, Nili F, Nayeri F, Esmaeilnia T, Dalili H, Shariat M. A Case Presentation of Voriconazole Therapy in a Brochopulmonary Dysplasia. Iranian Journal of Neonatology. 2015;6(1):33-34.
BibTex	@article{ author = {Amini E and Nili F and Nayeri F and Esmaeilnia T and Dalili H and Shariat M}, title = {A Case Presentation of Voriconazole Therapy in a Brochopulmonary Dysplasia}, journal = {Iranian Journal of Neonatology}, volume = {6}, number = {1}, pages = {33-34}, year = {2015} }
RIS	TY - JOUR AU - Amini E AU - Nili F AU - Nayeri F AU - Esmaeilnia T AU - Dalili H AU - Shariat M TI - A Case Presentation of Voriconazole Therapy in a Brochopulmonary Dysplasia JO - Iranian Journal of Neonatology VL - 6 IS - 1 SP - 33 EP - 34 PY - 2015 ER -

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