Antioxidant Effects of Selenium in Adult Critically Ill Patients: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Antioxidant Effects of Selenium in Adult Critically Ill Patients: A Systematic Review and Meta-Analysis of Randomized Controlled Trials Publisher

Hasani M^{1, 2} ; Agh F³ ; Irandoost P⁴ ; Farsi F⁵ ; Khodabakhshi A⁶ ; Heshmati J⁷ ; Pizarro AB⁸ ; Aghamohamadi V⁹ ; Khazdouz M^{4, 10, 11}

Show Affiliations

1. Health Management and Social Development Research Center, Golestan University of Medical Sciences, Gorgan, Iran
2. Department of Nutritional Sciences, School of Health, Golestan University of Medical Sciences, Gorgan, Iran
3. Saveh University of Medical Sciences, Saveh, Iran
4. Department of Nutrition, School of Public Health, Iran University of Medical Sciences, Tehran, Iran
5. Minimally Invasive Surgery Research Center, Iran University of Medical Sciences, Tehran, Iran
6. Department of Nutrition, School of Public Health, Kerman University of Medical Sciences, Kerman, Iran
7. Songhor Healthcare Center, Kermanshah University of Medical Sciences, Kermanshah, Iran
8. Clinical Research Center, Fundacion Valle Del Lili, Cali, Colombia
9. Department of Nutrition, Khalkhal University of Medical Sciences, Ardabil, Iran
10. Growth and Development Research Center, Tehran University of Medical Sciences, Tehran, Iran
11. Nutrition Department, Iran University of Medical Science, Iran

Source: Topics in Clinical Nutrition Published:2023

Abstract

Oxidative stress is the fundamental etiology of inflammation and organ failure, and unfavorable consequences characterize critical illness. We searched systematically up to September 2021 to find related randomized controlled trials (RCTs) that investigated the effects of selenium in antioxidant markers of the critically ill. A total of 10 RCTs were included. The results indicated that selenium administration has no significant effects on glutathione peroxidase activity (standardized mean difference [SMD]: 1.67, 95% confidence interval [CI]: -0.01 to 3.35) and C-reactive protein levels (SMD: -0.21 mg/L, 95% CI: -0.45 to 0.03). Further trials are needed to prove the potential effects of selenium administration on antioxidant and inflammation markers. © 2023 Lippincott Williams and Wilkins. All rights reserved.

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Style	Citing Format
MLA	Hasani M, et al.. "Antioxidant Effects of Selenium in Adult Critically Ill Patients: A Systematic Review and Meta-Analysis of Randomized Controlled Trials." Topics in Clinical Nutrition, vol. 38, no. 3, 2023, pp. 224-238.
APA	Hasani M, Agh F, Irandoost P, Farsi F, Khodabakhshi A, Heshmati J, Pizarro AB, Aghamohamadi V, Khazdouz M (2023). Antioxidant Effects of Selenium in Adult Critically Ill Patients: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Topics in Clinical Nutrition, 38(3), 224-238.
Chicago	Hasani M, Agh F, Irandoost P, Farsi F, Khodabakhshi A, Heshmati J, Pizarro AB, Aghamohamadi V, Khazdouz M. "Antioxidant Effects of Selenium in Adult Critically Ill Patients: A Systematic Review and Meta-Analysis of Randomized Controlled Trials." Topics in Clinical Nutrition 38, no. 3 (2023): 224-238.
Harvard	Hasani M et al. (2023) 'Antioxidant Effects of Selenium in Adult Critically Ill Patients: A Systematic Review and Meta-Analysis of Randomized Controlled Trials', Topics in Clinical Nutrition, 38(3), pp. 224-238.
Vancouver	Hasani M, Agh F, Irandoost P, Farsi F, Khodabakhshi A, Heshmati J, et al.. Antioxidant Effects of Selenium in Adult Critically Ill Patients: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Topics in Clinical Nutrition. 2023;38(3):224-238.
BibTex	@article{ author = {Hasani M and Agh F and Irandoost P and Farsi F and Khodabakhshi A and Heshmati J and Pizarro AB and Aghamohamadi V and Khazdouz M}, title = {Antioxidant Effects of Selenium in Adult Critically Ill Patients: A Systematic Review and Meta-Analysis of Randomized Controlled Trials}, journal = {Topics in Clinical Nutrition}, volume = {38}, number = {3}, pages = {224-238}, year = {2023} }
RIS	TY - JOUR AU - Hasani M AU - Agh F AU - Irandoost P AU - Farsi F AU - Khodabakhshi A AU - Heshmati J AU - Pizarro AB AU - Aghamohamadi V AU - Khazdouz M TI - Antioxidant Effects of Selenium in Adult Critically Ill Patients: A Systematic Review and Meta-Analysis of Randomized Controlled Trials JO - Topics in Clinical Nutrition VL - 38 IS - 3 SP - 224 EP - 238 PY - 2023 ER -

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