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Serum C1q and Tumor Necrosis Factor (Tnf)-Related Protein 9 in Women With Polycystic Ovary Syndrome Publisher Pubmed



Forouhi N1 ; Saedisomeolia A1, 2 ; Djalali M1 ; Eshraghian MR3 ; Morshedzadeh N4 ; Zabetiantarghi F1 ; Mahmoudi M1
Authors

Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews Published:2016


Abstract

Aims: To compare CTRP9 levels in women with Polycystic Ovary Syndrome (PCOS) and without PCOS. Furthermore, to determine the correlation between serum CTRP9 levels and some variety of anthropometric and biochemical parameters. Methods: The study included 29 PCOS patients and 27 healthy volunteers of the same age and BMI. Body weight, height and waist circumference were assessed. Blood samples were taken for assessment of serum CTRP9 by enzyme-linked immunosorbent assay (ELISA) technique. In addition, blood samples were collected for fasting insulin, glucose, and lipid profiles, and homeostasis model of assessment-insulin resistance (HOMA-IR) values were calculated. Results: Similar serum CTRP9 were found in PCOS subjects and controls (8.8 ± 19.9 vs 5.0 ± 7.6 ng/mL). Serum CTRP9 concentration positively correlated with serum LDL-C and total cholesterol in patient group. However, no correlation between CTRP9 and other biochemical and anthropometric variables was found. Conclusion: Serum CTRP9 logs of PCOS participants exhibit a positive association with unfavorable lipid profile in this report. © 2016 Diabetes India
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