Association of Blood Pressure Control, Lifestyle and Socioeconomic Status With Self-Rated Health in Patients With Hypertension: A National Cross-Sectional Study Publisher Pubmed



Behgam N ; Karimi Ghahfarokhi M ; Azizpour Y ; Naderyan Feli S ; Mozafari S ; Lotfaliany M ; Tohidinik HR ; Kompani F ; Rezaei N ; Djalalinia S
Source: BMJ Open Published:2025

Abstract

Objectives To examine demographic, behavioural and clinical determinants of self-rated health (SRH) among Iranian adults with hypertension (HTN), with a particular focus on the association between blood pressure (BP) control and perceived health. Design National cross-sectional analysis of 15 predictors spanning demographic, lifestyle and clinical domains. Setting 2021 Iranian STEPwise Approach to Non-communicable Disease Risk Factor Surveillance, a nationally representative survey. Participants A total of 8812 adults with HTN (mean age 56.97 years; 57% female). Controlled HTN was defined as systolic blood pressure <140 mm Hg and diastolic blood pressure <90 mm Hg among individuals on antihypertensive therapy. Primary and secondary outcome measures The primary outcome was SRH, measured on a standard EuroQol-Visual Analogue Scale (0–100). Results Controlled HTN was independently associated with higher SRH scores (β=1.31, 95% CI 0.07 to 2.54). Positive predictors of SRH included male gender (β=4.34, 95% CI 3.38 to 5.31), higher wealth (richest vs poorest: β=5.52, 95% CI 4.06 to 6.97), sufficient physical activity (β=4.38, 95% CI 3.48 to 5.28), healthier diet (β=3.06, 95% CI 1.99 to 4.14) and complementary insurance coverage (β=2.50, 95% CI 0.63 to 4.37). Significant negative predictors included diabetes mellitus (β=–4.23, 95% CI –5.59 to –3.26), dyslipidaemia (β=–3.61, 95% CI –4.62 to –2.59), people who smoke (β=–4.21, 95% CI –5.64 to –2.78) and older age. Notably, antihypertensive medication use showed one of the strongest negative associations with SRH (monotherapy: β=–4.83; combination therapy: β=–5.28), likely reflecting underlying disease severity and treatment burden. Conclusions Better SRH among hypertensive adults was associated with controlled BP, healthier lifestyle patterns and higher socioeconomic status. Conversely, comorbidities, smoking, older age and antihypertensive treatment were linked to poorer perceived health. Integrating SRH screening into HTN management may help identify vulnerable individuals and inform targeted interventions addressing behavioural and socioeconomic determinants of health. © Author(s) (or their employer(s)) 2025. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ Group.