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Salivary Duct Carcinoma With Late Distant Brain and Cutaneous Metastasis: A Case Report Publisher



Sadeghi HM1 ; Karimi A2 ; Rahpeima A3 ; Derakhshan S4
Authors
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Authors Affiliations
  1. 1. Oral & Maxillofacial Surgery Department, Taleghani Hospital, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  2. 2. Oral & Maxillofacial Surgery Department, Shariati Hospital, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran
  4. 4. Oral and Maxillofacial Pathology Department, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran

Source: Iranian Journal of Pathology Published:2020


Abstract

Salivary duct carcinoma (SDC) is a rare and highly aggressive salivary gland tumor with poor prognosis, rapid growth, distant metastasis, early regional metastasis, and a high rate of recurrence. The parotid gland is the most common site of involvement, and the lungs and the bones are the most common sites of distant metastasis of SDC. Herein, we present a case of SDC of the parotid gland in a 62-year-old male patient with an unusual metastasis to the skin of the primary site and brain 6 years after primary treatment, which comprised of total parotidectomy and radical neck dissection followed by radiotherapy. It is noteworthy that in few cases of SDC with infiltration, (and not in low-grade intraductal carcinoma of the salivary glands), routine treatment may not suffice, and long-term follow-up is highly recommended. © Iranian Society of Pathology. All rights reserved.