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Management of Gabapentin Misuse in a Patient With Previous History of Opioid Use Disorder: Case Report Publisher Pubmed



Jalilian Khave L1, 2 ; Noori M3 ; Rahimimovaghar A3 ; Noroozi A3
Authors
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Authors Affiliations
  1. 1. Department of Psychiatry, Yale School of Medicine, New Haven, CT, United States
  2. 2. Faculty of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  3. 3. Iranian National Center for Addiction Studies, Tehran University of Medical Sciences, Tehran, Iran

Source: Asian Journal of Psychiatry Published:2023


Abstract

We present a 37-year-old male who misuses 12 g of gabapentin per day associated with dependence and withdrawal. He had a previous history of opioid use disorder (OUD) which has been in remission. An outpatient gradual dose reduction regimen was tried and failed and the patient decided to discontinue gabapentin abruptly. Symptomatic medication to relieve gabapentin withdrawal was also unsuccessful and resulted in the reinstatement of OUD. Finally, the patient was stabilized using buprenorphine maintenance treatment and discontinued opioids and gabapentin misuse. The clinical implications and significance of taking regulatory actions to control gabapentin misuse have been discussed. © 2022 Elsevier B.V.