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Pathogenesis, Clinical Manifestations and Complications of Coronavirus Disease 2019 (Covid-19) Publisher Pubmed



Kordzadehkermani E1 ; Khalili H1 ; Karimzadeh I2
Authors

Source: Future Microbiology Published:2020


Abstract

Aim: Despite the similarities in the pathogenesis of the beta coronaviruses, the precise infective mechanisms of SARS-CoV-2 remain unclear. Objective: In this review, we aim to focus on the proposed theories behind the pathogenesis of SARS-CoV-2 and highlight the clinical complications related to COVID-19. Methods: We conducted a literature search in Pubmed, Scopus and Google Scholar for the relevant articles regarding clinical complications and pathogenesis of COVID-19. Results: Related articles were included and discussed. Conclusion: Respiratory system and the lungs are the most commonly involved sites of COVID-19 infection. Cardiovascular, liver, kidneys, gastrointestinal and central nervous systems are involved with different frequencies and degrees of severity. © 2020
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