Delphi: A Democratic and Cost-Effective Method of Consensus Generation in Transplantation

Delphi: A Democratic and Cost-Effective Method of Consensus Generation in Transplantation Publisher Pubmed

Afrouzian M¹ ; Kozakowski N² ; Liapis H^{3, 4} ; Broecker V⁵ ; Truong L⁶ ; Avilacasado C⁷ ; Regele H² ; Seshan S⁸ ; Ambruzs JM⁹ ; Farris AB¹⁰ ; Buob D¹¹ ; Chander PN¹² ; Cheraghvandi L¹³ ; Clahsenvan Groningen MC^{14, 15} Show All Authors

Afrouzian M¹
Kozakowski N²
Liapis H^{3, 4}
Broecker V⁵
Truong L⁶
Avilacasado C⁷
Regele H²
Seshan S⁸
Ambruzs JM⁹
Farris AB¹⁰
Buob D¹¹
Chander PN¹²
Cheraghvandi L¹³
Clahsenvan Groningen MC^{14, 15}
De Almeida Araujo S¹⁶
Ertoy Baydar D¹⁷
Formby M^{18, 19}
Galesic Ljubanovic D²⁰
Herrera Hernandez L²¹
Honsova E²²
Mohamed N²³
Ozluk Y²⁴
Rabant M²⁵
Royal V²⁶
Stevenson HL¹
Toniolo MF²⁷
Taheri D²⁸

Source: Transplant International Published:2023

Abstract

The Thrombotic Microangiopathy Banff Working Group (TMA-BWG) was formed in 2015 to survey current practices and develop minimum diagnostic criteria (MDC) for renal transplant TMA (Tx-TMA). To generate consensus among pathologists and nephrologists, the TMA BWG designed a 3-Phase study. Phase I of the study is presented here. Using the Delphi methodology, 23 panelists with >3 years of diagnostic experience with Tx-TMA pathology listed their MDC suggesting light, immunofluorescence, and electron microscopy lesions, clinical and laboratory information, and differential diagnoses. Nine rounds (R) of consensus resulted in MDC validated during two Rs using online evaluation of whole slide digital images of 37 biopsies (28 TMA, 9 non-TMA). Starting with 338 criteria the process resulted in 24 criteria and 8 differential diagnoses including 18 pathologic, 2 clinical, and 4 laboratory criteria. Results show that 3/4 of the panelists agreed on the diagnosis of 3/4 of cases. The process also allowed definition refinement for 4 light and 4 electron microscopy lesions. For the first time in Banff classification, the Delphi methodology was used to generate consensus. The study shows that Delphi is a democratic and cost-effective method allowing rapid consensus generation among numerous physicians dealing with large number of criteria in transplantation. Copyright © 2023 Afrouzian, Kozakowski, Liapis, Broecker, Truong, Avila-Casado, Regele, Seshan, Ambruzs, Farris, Buob, Chander, Cheraghvandi, Clahsen-van Groningen, de Almeida Araujo, Ertoy Baydar, Formby, Galesic Ljubanovic, Herrera Hernandez, Honsova, Mohamed, Ozluk, Rabant, Royal, Stevenson, Toniolo and Taheri.

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Style	Citing Format
MLA	Afrouzian M, et al.. "Delphi: A Democratic and Cost-Effective Method of Consensus Generation in Transplantation." Transplant International, vol. 36, no. , 2023, pp. -.
APA	Afrouzian M, Kozakowski N, Liapis H, Broecker V, Truong L, Avilacasado C, Regele H, Seshan S, Ambruzs JM, Farris AB, Buob D, Chander PN, Cheraghvandi L, Clahsenvan Groningen MC, De Almeida Araujo S, Ertoy Baydar D, Formby M, Galesic Ljubanovic D, Herrera Hernandez L, ... Taheri D (2023). Delphi: A Democratic and Cost-Effective Method of Consensus Generation in Transplantation. Transplant International, 36(), -.
Chicago	Afrouzian M, Kozakowski N, Liapis H, Broecker V, Truong L, Avilacasado C, Regele H, et al.. "Delphi: A Democratic and Cost-Effective Method of Consensus Generation in Transplantation." Transplant International 36, no. (2023): -.
Harvard	Afrouzian M et al. (2023) 'Delphi: A Democratic and Cost-Effective Method of Consensus Generation in Transplantation', Transplant International, 36(), pp. -.
Vancouver	Afrouzian M, Kozakowski N, Liapis H, Broecker V, Truong L, Avilacasado C, et al.. Delphi: A Democratic and Cost-Effective Method of Consensus Generation in Transplantation. Transplant International. 2023;36():-.
BibTex	@article{ author = {Afrouzian M and Kozakowski N and Liapis H and Broecker V and Truong L and Avilacasado C and Regele H and Seshan S and Ambruzs JM and Farris AB and Buob D and Chander PN and Cheraghvandi L and Clahsenvan Groningen MC and De Almeida Araujo S and Ertoy Baydar D and Formby M and Galesic Ljubanovic D and Herrera Hernandez L and Honsova E and Mohamed N and Ozluk Y and Rabant M and Royal V and Stevenson HL and Toniolo MF and Taheri D}, title = {Delphi: A Democratic and Cost-Effective Method of Consensus Generation in Transplantation}, journal = {Transplant International}, volume = {36}, number = {}, pages = {-}, year = {2023} }
RIS	TY - JOUR AU - Afrouzian M AU - Kozakowski N AU - Liapis H AU - Broecker V AU - Truong L AU - Avilacasado C AU - Regele H AU - Seshan S AU - Ambruzs JM AU - Farris AB AU - Buob D AU - Chander PN AU - Cheraghvandi L AU - Clahsenvan Groningen MC AU - De Almeida Araujo S AU - Ertoy Baydar D AU - Formby M AU - Galesic Ljubanovic D AU - Herrera Hernandez L AU - Honsova E AU - Mohamed N AU - Ozluk Y AU - Rabant M AU - Royal V AU - Stevenson HL AU - Toniolo MF AU - Taheri D TI - Delphi: A Democratic and Cost-Effective Method of Consensus Generation in Transplantation JO - Transplant International VL - 36 IS - SP - EP - PY - 2023 ER -

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