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Omega-3-Polyunsatured Fatty Acids (O3pufas), Compared to Placebo, Reduced Symptoms of Occupational Burnout and Lowered Morning Cortisol Secretion Publisher Pubmed



Jahangard L1 ; Hedayati M1 ; Abbasalipourkabir R2 ; Haghighi M1 ; Ahmadpanah M1 ; Faryadras M3 ; Mikoteit T4, 5 ; Sadeghi Bahmani D4, 6, 7, 8 ; Brand S4, 6, 7, 9
Authors
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Authors Affiliations
  1. 1. Research Center for Behavioral Disorders and Substance Abuse, Hamadan University of Medical sciences, Hamadan, Iran
  2. 2. Department of Biochemistry, Hamadan University of Medical Sciences, Hamadan, Iran
  3. 3. Department of Biostatistics and Epidemiology, School of Public Health, Hamadan University of Medical Sciences, Hamadan, Iran
  4. 4. University of Basel, Psychiatric Clinics, Center for Affective, Stress and Sleep Disorders, Basel, Switzerland
  5. 5. University of Basel, Psychiatric Hospital Solothurn, Solothurn, Switzerland
  6. 6. Kermanshah University of Medical Sciences (KUMS), Substance Abuse Prevention Research Center, Kermanshah, Iran
  7. 7. Kermanshah University of Medical Sciences (KUMS), Sleep Disorders Research Center, Kermanshah, Iran
  8. 8. Isfahan University of Medical Sciences, Neurosciences Research Center, Alzahra Research Institute, Isfahan, Iran
  9. 9. University of Basel, Department of Sport, Exercise and Health, Division of Sport Science and Psychosocial Health, Basel, Switzerland

Source: Psychoneuroendocrinology Published:2019


Abstract

Background:: Occupational burnout is both a serious health concern at both public and individual levels. Treatment options are psychopharmacological, psychological and physical activity-related interventions. Here, we tested whether, compared to placebo, omega-3-polyunsaturated fatty acids (O3PUFAs) have a positive impact on burnout and morning cortisol secretion. Method:: A total of 43 individuals (mean age: 38.4 years, 76.7% females) took part in the present double-blind and placebo-controlled intervention. Participants were randomly assigned either to the O3PUFA or to the placebo condition. At baseline and again eight weeks later, participants completed the Maslach Burnout Inventory and collected morning saliva samples for analysis of the cortisol awakening response (CAR). Results:: Emotional exhaustion and depersonalization decreased, and sense of personal accomplishment increased over time, but more so in the O3PUFA condition than in the placebo condition. Likewise, CAR decreased over time, but again more so in the O3PUFA condition than in the placebo condition. Conclusions:: The present pattern of results suggests that, compared to placebo, administration of daily omega-3-polyunsaturated fatty acids for eight consecutive weeks positively influences both psychological and physiological markers of occupational burnout. © 2019 Elsevier Ltd
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