Mortality Associated With Surgical Site Infections Following Cardiac Surgery: Insights From the International Id-Iri Study

Mortality Associated With Surgical Site Infections Following Cardiac Surgery: Insights From the International Id-Iri Study Publisher

Erdem H^{1, 2} ; Ankarali H³ ; Altawfiq JA^{4, 5} ; Angamuthu K⁶ ; Piljic D⁷ ; Umihanic A⁷ ; Dayyab F² ; Karamanlioglu D⁸ ; Pekok AU⁹ ; Caglasonmezer M¹⁰ ; Elkholy A¹¹ ; Gad MA¹¹ ; Velicki L¹² ; Akyildiz O¹³ Show All Authors

Erdem H^{1, 2}
Ankarali H³
Altawfiq JA^{4, 5}
Angamuthu K⁶
Piljic D⁷
Umihanic A⁷
Dayyab F²
Karamanlioglu D⁸
Pekok AU⁹
Caglasonmezer M¹⁰
Elkholy A¹¹
Gad MA¹¹
Velicki L¹²
Akyildiz O¹³
Altindis M¹⁴
Baskolelik D¹⁵
Erturksengel B¹⁶
Kara I¹⁷
Kahraman U¹⁸
Ozdemir M¹⁹
Caskurlu H²⁰
Cag Y²⁰
Alkhalifa A⁷
Hakamifard A^{21, 22}
Batinjan MKG¹²
Tahir M²³
Tukenmeztigen E¹⁶
Zajkowska J²⁴
Elkholy J²⁵
Gasparovic H²⁶
Filiz M¹
Gul O²⁷
Tehrani HA²⁸
Doyukkartal E²⁹
Aybarbilir Y⁸
Kahraman H²⁹
Mikulic H³⁰
Dayan S³¹
Cascio A³²
Yurdakul ES³³
Colkesen F³⁴
Karahangil K³⁵
Espinosa A²
Rahimi BA³⁶
Vangel Z³⁷
Fasciana T³⁸
Giammanco A³⁸

Source: IJID Regions Published:2025

Abstract

Objectives: Surgical site infections (SSIs) after cardiac surgery increase morbidity and mortality rates. This multicenter study aimed to identify mortality risk factors associated with SSIs after heart surgery. Methods: Conducted from January to March 2023, this prospective study included 167 patients aged >16 years with post-heart surgery SSIs. The primary focus was the 30-day mortality. Univariate analysis and multivariate logistic regression utilizing the backward elimination method were used to establish the final model. Results: Several factors significantly correlated with mortality. These included urinary catheterization (odds ratio [OR] 14.197; 90% confidence interval [CI] 12.198-91.721]), emergent surgery (OR 8.470 [90% CI 2.028-35.379]), valvular replacement (OR 4.487 [90% CI 1.001-20.627]), higher quick Sequential Organ Failure Assessment scores (OR 3.147 [90% CI 1.450-6.827]), advanced age (OR 1.075 [90% CI 1.020-1.132]), and postoperative re-interventions within 30 days after SSI (OR 14.832 [90% CI 2.684-81.972]). No pathogens were isolated from the wound cultures of 53 (31.7%) patients. A total of 43.1% of SSIs (n = 72) were due to gram-positive microorganisms, whereas 27.5% of cases (n = 46) involved gram-negatives. Among the gram-positive bacteria, Staphylococci (n = 30, 17.9%) were the predominant microorganisms, whereas Klebsiella (n = 16, 9.6%), Escherichia coli (n = 9, 5.4%), and Pseudomonas aeruginosa (n = 7, 4.2%) were the most prevalent. Conclusions: To mitigate mortality after heart surgery, stringent infection control measures and effective surgical antisepsis are crucial, particularly, in the elderly. The clinical progression of the disease is reflected by the quick Sequential Organ Failure Assessment score and patient re-intervention, and effective treatment is another essential component of SSI management. © 2025 The Authors

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Style	Citing Format
MLA	Erdem H, et al.. "Mortality Associated With Surgical Site Infections Following Cardiac Surgery: Insights From the International Id-Iri Study." IJID Regions, vol. 14, no. , 2025, pp. -.
APA	Erdem H, Ankarali H, Altawfiq JA, Angamuthu K, Piljic D, Umihanic A, Dayyab F, Karamanlioglu D, Pekok AU, Caglasonmezer M, Elkholy A, Gad MA, Velicki L, Akyildiz O, Altindis M, Baskolelik D, Erturksengel B, Kara I, Kahraman U, ... Giammanco A (2025). Mortality Associated With Surgical Site Infections Following Cardiac Surgery: Insights From the International Id-Iri Study. IJID Regions, 14(), -.
Chicago	Erdem H, Ankarali H, Altawfiq JA, Angamuthu K, Piljic D, Umihanic A, Dayyab F, et al.. "Mortality Associated With Surgical Site Infections Following Cardiac Surgery: Insights From the International Id-Iri Study." IJID Regions 14, no. (2025): -.
Harvard	Erdem H et al. (2025) 'Mortality Associated With Surgical Site Infections Following Cardiac Surgery: Insights From the International Id-Iri Study', IJID Regions, 14(), pp. -.
Vancouver	Erdem H, Ankarali H, Altawfiq JA, Angamuthu K, Piljic D, Umihanic A, et al.. Mortality Associated With Surgical Site Infections Following Cardiac Surgery: Insights From the International Id-Iri Study. IJID Regions. 2025;14():-.
BibTex	@article{ author = {Erdem H and Ankarali H and Altawfiq JA and Angamuthu K and Piljic D and Umihanic A and Dayyab F and Karamanlioglu D and Pekok AU and Caglasonmezer M and Elkholy A and Gad MA and Velicki L and Akyildiz O and Altindis M and Baskolelik D and Erturksengel B and Kara I and Kahraman U and Ozdemir M and Caskurlu H and Cag Y and Alkhalifa A and Hakamifard A and Batinjan MKG and Tahir M and Tukenmeztigen E and Zajkowska J and Elkholy J and Gasparovic H and Filiz M and Gul O and Tehrani HA and Doyukkartal E and Aybarbilir Y and Kahraman H and Mikulic H and Dayan S and Cascio A and Yurdakul ES and Colkesen F and Karahangil K and Espinosa A and Rahimi BA and Vangel Z and Fasciana T and Giammanco A}, title = {Mortality Associated With Surgical Site Infections Following Cardiac Surgery: Insights From the International Id-Iri Study}, journal = {IJID Regions}, volume = {14}, number = {}, pages = {-}, year = {2025} }
RIS	TY - JOUR AU - Erdem H AU - Ankarali H AU - Altawfiq JA AU - Angamuthu K AU - Piljic D AU - Umihanic A AU - Dayyab F AU - Karamanlioglu D AU - Pekok AU AU - Caglasonmezer M AU - Elkholy A AU - Gad MA AU - Velicki L AU - Akyildiz O AU - Altindis M AU - Baskolelik D AU - Erturksengel B AU - Kara I AU - Kahraman U AU - Ozdemir M AU - Caskurlu H AU - Cag Y AU - Alkhalifa A AU - Hakamifard A AU - Batinjan MKG AU - Tahir M AU - Tukenmeztigen E AU - Zajkowska J AU - Elkholy J AU - Gasparovic H AU - Filiz M AU - Gul O AU - Tehrani HA AU - Doyukkartal E AU - Aybarbilir Y AU - Kahraman H AU - Mikulic H AU - Dayan S AU - Cascio A AU - Yurdakul ES AU - Colkesen F AU - Karahangil K AU - Espinosa A AU - Rahimi BA AU - Vangel Z AU - Fasciana T AU - Giammanco A TI - Mortality Associated With Surgical Site Infections Following Cardiac Surgery: Insights From the International Id-Iri Study JO - IJID Regions VL - 14 IS - SP - EP - PY - 2025 ER -

Style

Citing Format

MLA

Erdem H, et al.. "Mortality Associated With Surgical Site Infections Following Cardiac Surgery: Insights From the International Id-Iri Study." IJID Regions, vol. 14, no. , 2025, pp. -.

APA

Erdem H, Ankarali H, Altawfiq JA, Angamuthu K, Piljic D, Umihanic A, Dayyab F, Karamanlioglu D, Pekok AU, Caglasonmezer M, Elkholy A, Gad MA, Velicki L, Akyildiz O, Altindis M, Baskolelik D, Erturksengel B, Kara I, Kahraman U, ... Giammanco A (2025). Mortality Associated With Surgical Site Infections Following Cardiac Surgery: Insights From the International Id-Iri Study. IJID Regions, 14(), -.

Chicago

Erdem H, Ankarali H, Altawfiq JA, Angamuthu K, Piljic D, Umihanic A, Dayyab F, et al.. "Mortality Associated With Surgical Site Infections Following Cardiac Surgery: Insights From the International Id-Iri Study." IJID Regions 14, no. (2025): -.

Harvard

Erdem H et al. (2025) 'Mortality Associated With Surgical Site Infections Following Cardiac Surgery: Insights From the International Id-Iri Study', IJID Regions, 14(), pp. -.

Vancouver

Erdem H, Ankarali H, Altawfiq JA, Angamuthu K, Piljic D, Umihanic A, et al.. Mortality Associated With Surgical Site Infections Following Cardiac Surgery: Insights From the International Id-Iri Study. IJID Regions. 2025;14():-.

BibTex

@article{ author = {Erdem H and Ankarali H and Altawfiq JA and Angamuthu K and Piljic D and Umihanic A and Dayyab F and Karamanlioglu D and Pekok AU and Caglasonmezer M and Elkholy A and Gad MA and Velicki L and Akyildiz O and Altindis M and Baskolelik D and Erturksengel B and Kara I and Kahraman U and Ozdemir M and Caskurlu H and Cag Y and Alkhalifa A and Hakamifard A and Batinjan MKG and Tahir M and Tukenmeztigen E and Zajkowska J and Elkholy J and Gasparovic H and Filiz M and Gul O and Tehrani HA and Doyukkartal E and Aybarbilir Y and Kahraman H and Mikulic H and Dayan S and Cascio A and Yurdakul ES and Colkesen F and Karahangil K and Espinosa A and Rahimi BA and Vangel Z and Fasciana T and Giammanco A}, title = {Mortality Associated With Surgical Site Infections Following Cardiac Surgery: Insights From the International Id-Iri Study}, journal = {IJID Regions}, volume = {14}, number = {}, pages = {-}, year = {2025} }

RIS

TY - JOUR
AU - Erdem H
AU - Ankarali H
AU - Altawfiq JA
AU - Angamuthu K
AU - Piljic D
AU - Umihanic A
AU - Dayyab F
AU - Karamanlioglu D
AU - Pekok AU
AU - Caglasonmezer M
AU - Elkholy A
AU - Gad MA
AU - Velicki L
AU - Akyildiz O
AU - Altindis M
AU - Baskolelik D
AU - Erturksengel B
AU - Kara I
AU - Kahraman U
AU - Ozdemir M
AU - Caskurlu H
AU - Cag Y
AU - Alkhalifa A
AU - Hakamifard A
AU - Batinjan MKG
AU - Tahir M
AU - Tukenmeztigen E
AU - Zajkowska J
AU - Elkholy J
AU - Gasparovic H
AU - Filiz M
AU - Gul O
AU - Tehrani HA
AU - Doyukkartal E
AU - Aybarbilir Y
AU - Kahraman H
AU - Mikulic H
AU - Dayan S
AU - Cascio A
AU - Yurdakul ES
AU - Colkesen F
AU - Karahangil K
AU - Espinosa A
AU - Rahimi BA
AU - Vangel Z
AU - Fasciana T
AU - Giammanco A
TI - Mortality Associated With Surgical Site Infections Following Cardiac Surgery: Insights From the International Id-Iri Study
JO - IJID Regions
VL - 14
IS -
SP -
EP -
PY - 2025
ER -

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